Daily Archives: August 11, 2021
M-A: Asymptomatic SARS-CoV-2 infection – “we estimate that the percentage of infections that never developed clinical symptoms, and thus were truly asymptomatic, was 35.1%”.
11 Aug, 2021 | 08:49h | UTC
Commentary on Twitter
The best comprehensive review of the asymptomatic status with Covid, >350 studies, just out @PNASNews https://t.co/xyfgyGXANL
Overall: true, never had symptoms 35%; children 47%@Pratha_Sah @Alison_Galvani @MeaganCFitz @YaleSPH & colleagues
(wonder what the rate is w/ Delta) pic.twitter.com/9W6wbvQno6— Eric Topol (@EricTopol) August 10, 2021
PRINCIPLE RCT: Inhaled budesonide improves time to recovery from COVID-19 in people at high risk of complications in the community.
11 Aug, 2021 | 08:52h | UTCInvited Commentary: The use of inhaled corticosteroids in early-stage COVID-19
WHO Guidance for surveillance of SARS-CoV-2 variants.
11 Aug, 2021 | 08:50h | UTC
Commentary on Twitter (thread – click for more)
? WHO guidance for national surveillance of #COVID19 virus variants ?https://t.co/YHRsazZhPA
Standardizing the monitoring & reporting of the variants will give us a better understanding of the virus at a global scale. pic.twitter.com/VNcxv8gyaa
— World Health Organization (WHO) (@WHO) August 10, 2021
M-A: More than 50 long-term effects of COVID-19.
11 Aug, 2021 | 08:47h | UTCRelated:
Cohort study: Risk factors for long covid in previously hospitalized children.
Viewpoint: The road to addressing Long Covid.
Review: Long covid—mechanisms, risk factors, and management.
Review: Symptoms, complications and management of long COVID.
Studies elucidate poorly understood long COVID.
Long Covid: Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds.
[Preprint] Long Covid: Third of people infected have long term symptoms.
Almost 25% of COVID-19 patients develop long-lasting symptoms, according to a new report.
Perspective | The four most urgent questions about long COVID.
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
Report: 376,000 people in UK have had long Covid symptoms for at least a year.
One third of patients hospitalized with COVID-19 have lung changes after a year
Perspective | They Tested Negative for Covid. Still, They Have Long Covid Symptoms.
Cohort study: One in ten have long-term effects 8 months following mild COVID-19
Long Covid Implications for the workplace
Long Covid in the UK – More than a million affected in February, survey suggests
Covid-19: Middle aged women face greater risk of debilitating long term symptoms
Persistent neurologic symptoms and cognitive dysfunction in non‐hospitalized Covid‐19 “long haulers”
Review | Post-acute COVID-19 syndrome
Long Covid | Four-month clinical status of a cohort of patients after hospitalization for COVID-19
Perspective | Long Covid isn’t as unique as we thought
Attributes and predictors of long COVID
WHO Report: Preparing for Long COVID 2021
Long Covid: Sequelae in adults at 6 Months after COVID-19 infection
How many people get ‘long COVID’ – and who is most at risk?
Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline
Patients, clinicians seek answers to the mystery of ‘Long COVID’
Long Covid: 6-month consequences of COVID-19 in patients discharged from hospital
NICE Guideline: Managing the long-term effects of COVID-19
Commentary on Twitter
Nuestro estudio sobre Covid ?Persistente o de Largo recorrido se ha publicado finalmente en @SciReports
?https://t.co/ATFO5QO3kF pic.twitter.com/qwBikXyqll— Sonia Villapol (@svillapol) August 10, 2021
BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.
11 Aug, 2021 | 08:37h | UTCEffect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU? – JAMA (free for a limited period)
Video: Balanced Solution vs. Saline in Intensive Care Study
Opinion | We should not dismiss the possibility of eradicating COVID-19: comparisons with smallpox and polio.
11 Aug, 2021 | 08:42h | UTC
CDC Report: COVID-19 morbidity and mortality far exceed the potential risks of rare side effects caused by vaccines.
11 Aug, 2021 | 08:45h | UTC
USPSTF Statement recommends screening for gestational diabetes in asymptomatic pregnant persons at 24 weeks of gestation or after.
11 Aug, 2021 | 08:35h | UTCEvidence report: Screening for Gestational Diabetes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorial: Screening for Gestational Diabetes – JAMA
Author interview: USPSTF Recommendation: Screening for Gestational Diabetes
JAMA Patient Page: Screening for Gestational Diabetes
Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.
11 Aug, 2021 | 08:44h | UTCRelated:
NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.
Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)
Commentary on Twitter
Big day! Our paper is now published in JAMA Cardiology! @JAMA_current @JAMACardio @JAMANetwork
COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia with Cerebral Venous Sinus Thrombosis
Full-text: https://t.co/XoY0xoztXT pic.twitter.com/IfAmsxomPy
— John G. Rizk (@JohnGRizk) August 10, 2021
BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.
11 Aug, 2021 | 08:39h | UTCEffect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill PatientsThe BaSICS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Does Crystalloid Composition or Rate of Fluid Administration Make a Difference When Resuscitating Patients in the ICU? – JAMA (free for a limited period)
Video: Balanced Solution vs. Saline in Intensive Care Study
Commentary on Twitter
Among critically ill patients requiring fluid challenges, treatment with a balanced solution compared with saline solution did not significantly reduce 90-day mortality https://t.co/LNDtsxxiwB
— JAMA (@JAMA_current) August 10, 2021
Cluster RCT: Vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh conferred 85% total protection.
11 Aug, 2021 | 08:28h | UTCInvited commentary: Salmonella Typhi Vi polysaccharide conjugate vaccine protects infants and children against typhoid fever – The Lancet
New WHO toolkit promotes inclusion of people with dementia in society.
11 Aug, 2021 | 08:31h | UTCNew WHO toolkit promotes inclusion of people with dementia in society – World Health Organization
See Guidance: Towards a dementia inclusive society: WHO toolkit for dementia-friendly initiatives (DFIs) – World Health Organization
Commentary on Twitter (thread – click for more)
? toolkit to promote a #dementia-inclusive society launched. It will helps countries raise public awareness and understanding of dementia to support people living with dementia to remain in, and be a significant part of, their communities.
? https://t.co/blpDQHUSWM pic.twitter.com/D5MIM5jdlr
— World Health Organization (WHO) (@WHO) August 10, 2021
Hemodynamics for the Heart Failure Clinician: A State-of-the-Art Review.
11 Aug, 2021 | 08:32h | UTCHemodynamics for the Heart Failure Clinician: A State-of-the-Art Review – Journal of Cardiac Failure
EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumors.
11 Aug, 2021 | 08:29h | UTCCommentary: New guidelines for the diagnosis and treatment of brain metastases – University of Vienna
Commentary on Twitter
Just out? @EANOassociation-ESMO Guidelines for the management of patients with #brain metastasis from solid #tumours: find out the latest recommendations, immunohistochemical markers for #carcinoma of unknown primary and treatment algorithms ? https://t.co/CriaZKxFJr #btsm pic.twitter.com/0yQqmJMzT1
— ESMO – Eur. Oncology (@myESMO) August 5, 2021
RCT: Triaging acute pulmonary embolism for home treatment by Hestia vs. simplified PESI criteria – the tools were similarly effective, and more than a third of patients were treated at home with a low incidence of complications.
11 Aug, 2021 | 08:27h | UTC
Commentary on Twitter
Triaging acute pulmonary embolism for home treatment by Hestia or simplified PESI criteria: the HOME-PE randomized trial #EHJ #PE #PERThttps://t.co/gszusChSyU pic.twitter.com/NOyKYsVQHo
— EHJ Editor-in-Chief (@ehj_ed) August 10, 2021
Cystic pancreatic lesions: MR imaging findings and management.
11 Aug, 2021 | 08:21h | UTCCystic pancreatic lesions: MR imaging findings and management – Insights into Imaging
Related:
Recommendations for the management of incidental pancreatic findings in adults.
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
Management of Pancreatic Cystic Lesions
Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions
Review: Pancreatic Cystic Lesions
Guidelines on pancreatic cystic neoplasms
RCT: Computer-assisted individualized hemodynamic management reduces intraoperative hypotension in intermediate- and high-risk surgery – larger trials with patient-relevant outcomes are required.
11 Aug, 2021 | 08:25h | UTCVideo: Computer-assisted individualized hemodynamic management reduces intraoperative hypotension
Science, Medicine, And The Anesthesiologist | August 2021: Key Papers from the Most Recent Literature Relevant to Anesthesiologists.
11 Aug, 2021 | 08:24h | UTCScience, Medicine, and the Anesthesiologist – Anesthesiology
Systematic review: Prescribing practices, patterns, and potential harms in patients receiving palliative care – “many patients receiving palliative care receive multiple medications closer to the time of death”.
11 Aug, 2021 | 08:23h | UTC
Commentary on Twitter
Useful overview of observational research about prescribing in #palliativecare – more work needed to assess appropriateness, potential harms and prescribing trendshttps://t.co/7abM5ANEH0
— Deprescribing (@Deprescribing) August 10, 2021