Daily Archives: July 15, 2021
RCT: Bamlanivimab plus Etesevimab reduce mortality and hospitalization in ambulatory patients with early Covid-19 (within 3 days of a positive test) who are at risk for clinical deterioration (i.e., older people, obese, diabetics, immunocompromised, with CV disease).
15 Jul, 2021 | 09:26h | UTCBamlanivimab plus Etesevimab in Mild or Moderate Covid-19 – New England Journal of Medicine
Long COVID and kids: scientists race to find answers – “Children get long COVID too, but researchers are still working to determine how frequently and how severely”.
15 Jul, 2021 | 09:23h | UTCLong COVID and kids: scientists race to find answers – Nature
Millions of children worldwide missed routine vaccinations during the pandemic, study suggests.
15 Jul, 2021 | 09:24h | UTCMillions of children worldwide missed routine vaccinations during the pandemic, study suggests – CNN
Invited Commentary: Disruptions to childhood immunisation due to the COVID-19 pandemic – The Lancet
COVID and the brain: researchers zero in on how damage occurs.
15 Jul, 2021 | 09:18h | UTCCOVID and the brain: researchers zero in on how damage occurs – Nature
Why aren’t diseases like HIV and malaria, which still kill millions of people a year, called pandemics? – “HIV and AIDS, tuberculosis, and malaria shouldn’t be labeled as “just” epidemics or endemic. They are pandemics that have been beaten in rich countries”.
15 Jul, 2021 | 09:22h | UTC
Commentary on Twitter
"HIV, TB, and malaria shouldn’t be labeled as “just” epidemics or endemic. They are pandemics that have been beaten in rich countries. Allowing them to persist elsewhere is a policy choice and a budgetary decision"https://t.co/MVCS960cN5
— Madhu Pai, MD, PhD (@paimadhu) July 14, 2021
Study shows the viral loads in the Delta infections are ~1000 times higher than those in the earlier strain infections on the day when viruses are firstly detected.
15 Jul, 2021 | 09:20h | UTCCommentary: The Delta Variant Isn’t Just Hyper-Contagious. It Also Grows More Rapidly Inside You – NPR
Related: WHO: Delta variant is ‘most transmissible’ identified so far. AND Increased transmissibility and global spread of SARS-CoV-2 variants of concern – “Estimated transmissibility increases of alpha 29% (95% CI: 24–33), beta 25% (95% CI: 20–30), gamma 38% (95% CI: 29–48) & delta 97% (95% CI: 76–117)”.
Commentary on Twitter
Part of the challenge that Delta presents may be tied to this finding
The variant's viral load ~1,000X higher than previous strains (reflected by low CTs), more infectious in the early stages of the illnesshttps://t.co/09CDQFwCSV pic.twitter.com/mjIfcNTYlO— Eric Topol (@EricTopol) July 9, 2021
[Preprint] Brain imaging before and after COVID-19 in UK Biobank.
15 Jul, 2021 | 09:17h | UTCBrain imaging before and after COVID-19 in UK Biobank – medRxiv
Commentaries: COVID linked to loss of brain tissue: but correlation doesn’t prove causation – The Conversation AND COVID-19 survivors may suffer from a loss of gray matter and other brain tissue over time, a long-term study suggests – Business Insider
WHO releases first-ever global guidance for country validation of viral hepatitis B and C elimination.
15 Jul, 2021 | 09:16h | UTCSee guidance: Interim guidance for country validation of viral hepatitis elimination – World Health Organization
Radiation therapy-associated toxicity: Etiology, management, and prevention.
15 Jul, 2021 | 09:13h | UTC
US Report: Death rates are declining for many common cancers, including lung cancer and melanoma.
15 Jul, 2021 | 09:11h | UTCCommentaries: Death rates are declining for many common cancers in the U.S., report finds – STAT AND Annual report to the nation: Rapid decrease in lung cancer and melanoma deaths – American Cancer Society
Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.
15 Jul, 2021 | 09:14h | UTC[131] Tramadol: Where do we go from here? – Therapeutic Initiative
RCT: Intravitreal ranibizumab vs. aflibercept vs. bevacizumab for macular edema due to central retinal vein occlusion.
15 Jul, 2021 | 09:09h | UTC
Cohort study: Increased risk of long-term risk of anemia after bariatric surgery – Compared with the control group, the incidence of anemia was higher in the gastric bypass group (HR 5.05), the vertical-banded gastroplasty group (HR 2.67), and the gastric banding group (HR 2.76).
15 Jul, 2021 | 09:10h | UTCLong-term risk of anaemia after bariatric surgery: results from the Swedish Obese Subjects study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Opinion | “Negative Secular Trends in Medicine: Part VIII: Practicing Physicians Posting on Social Media”.
15 Jul, 2021 | 09:08h | UTC
Consensus Guidance: Budd-Chiari syndrome.
15 Jul, 2021 | 09:07h | UTC
A consensus integrated care pathway for patients with primary biliary cholangitis.
15 Jul, 2021 | 09:06h | UTC
M-A: Utility of intravenous Alteplase prior to endovascular stroke treatment.
15 Jul, 2021 | 09:03h | UTCUtility of Intravenous Alteplase Prior to Endovascular Stroke Treatment: A Systematic Review and Meta-analysis of RCTs – Neurology (link to abstract – $ for full-text)
Commentary: Direct thrombectomy, bridging therapy confer similar functional outcomes in stroke – Healio (free registration required)
Commentary on Twitter
Via @GreenJournal: For #patients with acute large vessel occlusion, functional outcomes were similar for those receiving direct #endovascular treatment and bridging therapy.#NeuroTwitter #neurology https://t.co/LweNGwOhVB pic.twitter.com/jqgZyV9ZOA
— Neurology Today (@NeurologyToday) June 22, 2021
Consensus paper: Clinical indications for image-guided interventional procedures in the musculoskeletal system.
15 Jul, 2021 | 09:05h | UTCOther articles from the series:
Part III – nerves of the upper limb
Sarcoidosis: A clinical overview from symptoms to diagnosis.
15 Jul, 2021 | 08:58h | UTCSarcoidosis: A Clinical Overview from Symptoms to Diagnosis – Cells
Diagnosis and clinical management of hepatosplenic schistosomiasis: A scoping review of the literature.
15 Jul, 2021 | 09:02h | UTC
Acute promyelocytic leukemia current treatment algorithms.
15 Jul, 2021 | 09:01h | UTCAcute promyelocytic leukemia current treatment algorithms – Blood Cancer Journal