Daily Archives: July 7, 2021
M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”.
7 Jul, 2021 | 09:02h | UTCEditorial: IL-6 Receptor Antagonist Therapy for Patients Hospitalized for COVID-19: Who, When, and How? – JAMA
Commentaries: Interleukin-6 antagonists improve outcomes in hospitalised COVID-19 patients – King’s College London AND WHO advises 2 monoclonal antibodies for severe COVID – CIDRAP
Commentary on Twitter (thread – click for more)
https://twitter.com/msh_manu/status/1412473073715056645
A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.
7 Jul, 2021 | 09:03h | UTCA living WHO guideline on drugs for covid-19 – The BMJ
Commentary on Twitter
The latest version of this @WHO living guidance provides a strong recommendation for interleukin-6 (IL-6) receptor blockers (tocilizumab or sarilumab) in patients with severe or critical covid-19. Read the updated WHO guideline on drugs for #COVID19 https://t.co/FUb9yzFRwo
— The BMJ (@bmj_latest) July 6, 2021
Wear a mask if you’re vaccinated? Why the WHO and CDC don’t have the same guidance.
7 Jul, 2021 | 08:58h | UTCWear a mask if you’re vaccinated? Why the WHO and CDC don’t have the same guidance – C|Net
Related: WHO urges fully vaccinated people to continue to wear masks as delta Covid variant spreads. AND What the science says about lifting mask mandates – “Wearing masks should probably be one of the last things we stop doing”. AND CDC says fully vaccinated Americans can go indoors and outdoors without masks.
WHO recommends life-saving interleukin-6 receptor blockers for COVID-19 and urges producers to join efforts to rapidly increase access – “These are the first drugs found to be effective against COVID-19 since corticosteroids were recommended by WHO in September 2020”.
7 Jul, 2021 | 09:00h | UTC
Commentary on Twitter (thread – click for more)
🆕 treatment recommendation from WHO:
WHO recommends life-saving interleukin-6 receptor blockers to treat #COVID19 and urges producers to join efforts to rapidly increase access.👉https://t.co/h4IcZad2VA pic.twitter.com/YXPkuBVwY4
— World Health Organization (WHO) (@WHO) July 6, 2021
Pediatric telehealth in the COVID-19 pandemic era and beyond.
7 Jul, 2021 | 08:56h | UTCPediatric Telehealth in the COVID-19 Pandemic Era and Beyond – Pediatrics
RCOG Guidance: Coronavirus (COVID-19) Vaccination in Pregnancy.
7 Jul, 2021 | 08:53h | UTCCoronavirus (COVID-19) Vaccination in Pregnancy – Royal College of Obstetricians & Gynaecologists
See also: Resources and FAQs – Royal College of Obstetricians & Gynaecologists
Commentary on Twitter
We have published an interim update to the main coronavirus and pregnancy guidance to summarise the guidance on COVID-19 vaccination and pregnancy. Find out more: https://t.co/2YDyZFrVWJ pic.twitter.com/KnwXDvZls2
— RoyalCollegeObsGyn (@RCObsGyn) July 1, 2021
SAEM Guidelines for reasonable and appropriate care in the emergency department (GRACE): Recurrent, low-risk chest pain in the emergency department.
7 Jul, 2021 | 08:48h | UTCNews release: SAEM publishes GRACE guidelines for recurrent, low-risk chest pain care in the ED – Society for Academic Emergency Medicine
Invited commentaries: GRACE-recurrent low-risk chest pain: A user’s guide AND Navigating uncertainty with GRACE: Society for Academic Emergency Medicine’s guidelines for reasonable and appropriate care in the emergency department
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
7 Jul, 2021 | 08:52h | UTC
WHO pledges extensive commitments towards women’s empowerment and health.
7 Jul, 2021 | 08:49h | UTCWHO pledges extensive commitments towards women’s empowerment and health – World Health Organization
Commentary on Twitter (thread – click for more)
WHO pledges extensive commitments towards women’s empowerment & health with focus on:
✅ ending gender-based violence
✅ advancing sexual & reproductive health & rights
✅ supporting health workers, as well as feminist movements & leadershiphttps://t.co/52pdTaWPTY #ActForEqual— World Health Organization (WHO) (@WHO) July 5, 2021
RCT: Cardiovascular and renal outcomes with Efpeglenatide (a GLP-1 receptor agonist) in Type 2 Diabetes.
7 Jul, 2021 | 08:45h | UTC
New WHO recommendations for screening to prevent cervical cancer – the new guideline recommends an HPV DNA based test every 5 years as the preferred method, rather than visual inspection with acetic acid (VIA) or cytology (Pap smear).
7 Jul, 2021 | 08:51h | UTCNews release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 recommendations for screening and treatment to prevent #CervicalCancer will help countries take the next step towards elimination. Cervical #cancer is the 4th most common cancer among women worldwide 🌎🌍🌏
👉 https://t.co/2vfxqa9FMB pic.twitter.com/zC0h20nAce
— World Health Organization (WHO) (@WHO) July 6, 2021
RCT: Daratumumab-based treatment for immunoglobulin light-chain amyloidosis.
7 Jul, 2021 | 08:44h | UTC
RCT: An antibiotic-prescribing feedback to high-volume primary care physicians led to significant reductions in total and prolonged-duration antibiotic prescriptions, as well as drug costs.
7 Jul, 2021 | 08:47h | UTCEffect of Antibiotic-Prescribing Feedback to High-Volume Primary Care Physicians on Number of Antibiotic Prescriptions: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentary: Studies highlight impact of clinician feedback on antibiotic prescribing – CIDRAP
Commentary on Twitter (thread – click for more)
We conducted a randomized controlled trial of providing antibiotic prescribing feedback to high volume primary care physicians in Ontario, 🇨🇦 https://t.co/zmF2tvJ5n5
— Kevin Schwartz (@DrKevinSchwartz) July 6, 2021
RCT: Pectoral nerve blocks for breast augmentation surgery.
7 Jul, 2021 | 08:41h | UTCPectoral Nerve Blocks for Breast Augmentation Surgery: A Randomized, Double-blind, Dual-centered Controlled Trial – Anesthesiology (link to abstract – $ for full-text)
Commentary on Twitter
Better pain relief using PECS blocks in breast augmentation surgery. https://t.co/T0SIyR7zFn pic.twitter.com/4rrbj6eTFk
— Anesthesiology (@_Anesthesiology) June 29, 2021
RCT: Similar long-term survival after combined epidural–general anesthesia vs. general anesthesia alone.
7 Jul, 2021 | 08:39h | UTC
Commentary on Twitter
In elderly patients having major thoracic and abdominal surgery, combined epidural–general anesthesia with epidural analgesia did not improve overall or cancer-specific long-term mortality. https://t.co/rFyvUYO2LX
— Anesthesiology (@_Anesthesiology) June 21, 2021
A critical review on altmetrics: can we measure the social impact factor?
7 Jul, 2021 | 08:42h | UTCA critical review on altmetrics: can we measure the social impact factor? – Insights into Imaging
Related: Altmetric Score Has a Stronger Relationship With Article Citations Than Journal Impact Factor and Open Access Status: A Cross-Sectional Analysis of 4,022 Sports Science Articles – Journal of Orthopaedic & Sports Physical Therapy (link to abstract – $ for full-text)
Commentary on Twitter
My new paper about Altmetrics! An emergent topic in editorialism! @radiology_rsna @RadioGraphics @AcadRadiol @ajrRadiology @cannella_rob @radiologyCTI @cookyscan1 https://t.co/zadPpJi88x
— Cristina Garcia Villar (@villar_gar) July 2, 2021
RCT: A prevention program for insomnia in at-risk adolescents.
7 Jul, 2021 | 08:38h | UTCA Prevention Program for Insomnia in At-risk Adolescents: A Randomized Controlled Study – Pediatrics (link to abstract – $ for full-text)
Commentaries: Using a program to combat teen insomnia – Contemporary Pediatrics AND Cognitive behavioral program may prevent insomnia in at-risk adolescents – Medicom
M-A: Incidence and Relapse of Idiopathic Nephrotic Syndrome.
7 Jul, 2021 | 08:37h | UTCIncidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis – Pediatrics (link to abstract – $ for full-text)