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Daily Archives: June 29, 2021

IHME COVID-19 model has been updated for over 200 world locations.

29 Jun, 2021 | 10:13h | UTC

COVID-19 Projections – Institute for Health Metrics and Evaluation

Video: Insights from IHME’s latest COVID-19 model update

 

Commentary on Twitter

 


Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

29 Jun, 2021 | 10:09h | UTC

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy children and adolescents: a double-blind, randomised, controlled, phase 1/2 clinical trial – The Lancet Infectious Diseases

Invited commentary: COVID-19 vaccines for children younger than 12 years: are we ready? – The Lancet Infectious Diseases

 

Commentary on Twitter

 


SARS-CoV-2 mRNA vaccines induce persistent human germinal center responses, suggesting immunity will be long-lasting.

29 Jun, 2021 | 10:03h | UTC

SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses – Nature

Commentaries: Immune response to FDA-approved vaccines is strong and potentially long-lasting – News Medical

Related: A long-term perspective on immunity to COVID – “Clinical studies now indicate that immunity will be long-lasting”.

 

Commentary on Twitter (thread – click for more)

 


Case report: Thrombosis with Thrombocytopenia After the Messenger RNA–1273 Vaccine.

29 Jun, 2021 | 10:07h | UTC

Thrombosis With Thrombocytopenia After the Messenger RNA–1273 Vaccine – Annals of Internal Medicine

Commentary: Expert reaction to case report of from the U.S. of thrombosis with thrombocytopenia after the Moderna mRNA vaccine – Science Media Centre

 


[Preprint] 3rd AstraZeneca shot gives strong immunity.

29 Jun, 2021 | 10:01h | UTC

Study: 3rd AstraZeneca shot gives strong immunity – Reuters

Original Study (preprint): Tolerability and Immunogenicity After a Late Second Dose or a Third Dose of ChAdOx1 nCoV-19 (AZD1222) – SSRN/The Lancet

 


Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease”.

29 Jun, 2021 | 10:00h | UTC

Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – Clinical Infectious Diseases

Related: Ivermectin is the new hydroxychloroquine, take 2 – “Ivermectin shouldn’t be used to treat COVID-19 outside of the context of a well-designed clinical trial”.

 


WHO issues first global report on Artificial Intelligence (AI) in health and six guiding principles for its design and use.

29 Jun, 2021 | 09:56h | UTC

News release: WHO issues first global report on Artificial Intelligence (AI) in health and six guiding principles for its design and use – World Health Organization

Guidance: Ethics and governance of artificial intelligence for health – World Health Organization

Commentary: Artificial Intelligence ‘Very Promising’ for Health, Says WHO – Health Policy Watch

 

Commentary on Twitter (thread – click for more)

 


The COVID pandemic’s lingering impact on clinical trials – “Medical researchers are beginning to shift their focus away from COVID-19 — but the pandemic could continue to affect studies focused on other diseases.”

29 Jun, 2021 | 09:57h | UTC

The COVID pandemic’s lingering impact on clinical trials – Nature

 


Systematic review: the evidence behind robot-assisted abdominopelvic surgery – “there is currently no clear advantage with existing robotic platforms, which are costly and increase operative duration”.

29 Jun, 2021 | 09:55h | UTC

The Evidence Behind Robot-Assisted Abdominopelvic Surgery: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Robotic Platforms Not Superior for Abdominopelvic Surgery – HealthDay

 


Podcast | Evaluation and management of hypercalcemia.

29 Jun, 2021 | 09:51h | UTC

#281 Hypercalcemia: Calci-fun! with Dr. Carl Pallais – The Curbsiders

 


EBM Analysis | Does tranexamic acid work for everything? For anything?

29 Jun, 2021 | 09:53h | UTC

Does TXA work for everything? For anything? – First10EM

 


RCT: Similar outcomes with mycophenolate mofetil vs. azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression.

29 Jun, 2021 | 09:50h | UTC

Mycophenolate mofetil versus azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression (ATHENA): A pragmatic randomized trial – PLOS One

 


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