Daily Archives: June 28, 2021
Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.
28 Jun, 2021 | 10:01h | UTCCommentaries: Heterologous vaccine regimens against COVID-19 – The Lancet AND
Commentary on Twitter (thread – click for more)
NEW #COVID19 research—Phase 2 trial by @borobia_am, @antoniojcarcas
et al. reports BNT162b2 given as a 2nd dose in individuals prime vaccinated with ChAdOx1-S induced a robust immune response, with an acceptable and manageable reactogenicity profile. Read https://t.co/muL0XQxdjG. pic.twitter.com/BxPlXB8EF7— The Lancet (@TheLancet) June 26, 2021
WHO urges fully vaccinated people to continue to wear masks as delta Covid variant spreads.
28 Jun, 2021 | 09:55h | UTCWHO urges fully vaccinated people to continue to wear masks as delta Covid variant spreads – CNBC
Commentary on Twitter (thread – click for more)
⚠️WEAR MASK EVEN IF VACCINATED—Top @WHO leader urges masks against #DeltaVariant even if 2-dose vaxxed. "Vaccine alone won't stop community transmission. People need to use masks consistently, be in ventilated spaces—even if you're vaccinated" #COVID19?https://t.co/qPZTmcy9iW pic.twitter.com/j5V6fbHdoi
— Eric Feigl-Ding (@DrEricDing) June 26, 2021
Delta “Plus”: Scientists say too early to tell risk of Covid-19 variant.
28 Jun, 2021 | 09:53h | UTCDelta plus India: Scientists say too early to tell risk of Covid-19 variant – BBC
Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.
28 Jun, 2021 | 09:52h | UTCIs one vaccine dose enough if you’ve had COVID? What the science says – Nature
Commentary on Twitter
One vaccine dose for prior covid: @ElieDolgin reviews the recent data @Nature https://t.co/amJ4RcGtuW
Vaccination cards/proof should be modified here to equate prior covid as the 1st dose and not force people to get an unnecessary 2nd dose— Eric Topol (@EricTopol) June 27, 2021
Study finds 96.1% of patients objectively recovered from anosmia 1 year after COVID-19 diagnosis.
28 Jun, 2021 | 09:49h | UTCClinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis – JAMA Network Open
Commentary: Did Covid-19 take your taste and smell? Here’s when they may return – CNN AND Lost Sense of Smell Returns for Almost All COVID Survivors – HealthDay
WHO: Delta variant is ‘most transmissible’ identified so far.
28 Jun, 2021 | 09:58h | UTCWHO: Delta variant is ‘most transmissible’ identified so far – Associated Press
Related: Delta COVID variant fuels global surges, complicates reopenings – CIDRAP AND Delta variant triggers dangerous new phase in the pandemic – Science AND Delta coronavirus variant: scientists brace for impact – Nature AND Rapid displacement of SARS-CoV-2 variant B.1.1.7 by B.1.617.2 and P.1 in the United States – medRxiv AND COVID-19: The rise and rise of Delta – Sciblogs AND Increased transmissibility and global spread of SARS-CoV-2 variants of concern – “Estimated transmissibility increases of alpha 29% (95% CI: 24–33), beta 25% (95% CI: 20–30), gamma 38% (95% CI: 29–48) & delta 97% (95% CI: 76–117)”.
Putting people first in managing their health: new WHO guideline on self-care interventions – “Whether it’s for their experience of pregnancy and childbirth; managing fertility intentions, preventing sexually transmitted infections; enjoying better sexual health of themselves or their partner, or self-monitoring their blood pressure, access to quality self-care interventions can help meet people’s many health needs and rights”.
28 Jun, 2021 | 09:40h | UTCNews release: Putting people first in managing their health: new WHO guideline on self-care interventions – World Health Organization
See guidance: WHO consolidated guideline on self-care interventions for health
Commentary on Twitter (thread – click for more)
To celebrate #SelfCare Month WHO is releasing new guidelines on Self-Care Interventions for Health.
This new ? recognizes how people can actively take decisions for their own health and the health of their ♥️ ones. https://t.co/xzditNF4NI
— World Health Organization (WHO) (@WHO) June 25, 2021
IDSA Updated Covid-19 Guidance: Co-Infection and Antimicrobial Stewardship – “bacterial coinfections with SARS-CoV-2 infection are relatively infrequent (likely occurring in less than 10% of hospitalized COVID-19 patients)”.
28 Jun, 2021 | 09:51h | UTCCo-Infection and Antimicrobial Stewardship – Infectious Diseases Society of America
RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.
28 Jun, 2021 | 09:46h | UTC
Consensus Recommendations on the Treatment of Opioid Use Disorder in the Emergency Department.
28 Jun, 2021 | 09:43h | UTC
Impact factor abandoned by Dutch university in hiring and promotion decisions – “Faculty and staff members at Utrecht University will be evaluated by their commitment to open science”.
28 Jun, 2021 | 09:37h | UTCImpact factor abandoned by Dutch university in hiring and promotion decisions – Nature
Related: Open-access Science Funders Announce Price Transparency Rules for Publishers (several resources on the subject) AND A new mandate highlights costs, benefits of making all scientific articles free to read – Science AND A guide to Plan S: the open-access initiative shaking up science publishing – Nature
RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.
28 Jun, 2021 | 09:45h | UTCTirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Combo GIP/GLP-1 Drug Superior for HbA1c Reduction in T2D – MedPage Today (free registration required)
Guideline | Perimenopause and Postmenopause – Diagnosis and Interventions.
28 Jun, 2021 | 09:32h | UTC
AASLD Guideline: Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease.
28 Jun, 2021 | 09:33h | UTC