Daily Archives: June 9, 2021
[Preprint] RECOVERY trial finds aspirin does not improve survival for patients hospitalized with COVID-19.
9 Jun, 2021 | 08:28h | UTCNews Release: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19 – University of Oxford
Original Study: Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv
Commentary on Twitter (thread – click for more)
RECOVERY Pre-print: Aspirin
14,892 patients randomised to aspirin vs. usual care
– no impact on all-cause mortality (17% vs. 17%)
– similar results in all pre-specified subgroupshttps://t.co/ay5Xg4GBVD pic.twitter.com/aNJ09RTTOa— Martin Landray (@MartinLandray) June 8, 2021
COVID-19 Imaging: What we know now and what remains unknown.
9 Jun, 2021 | 08:27h | UTCCOVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology
Perspective | How COVID changed science.
9 Jun, 2021 | 08:24h | UTCHow COVID Changed Science – Scientific American
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
9 Jun, 2021 | 08:22h | UTC
M-A: Hospital-at-home interventions for patients with chronic disease who present to the emergency department – similar mortality risk, lower risk for readmission, lower depression and anxiety scores, and a lower risk for long-term care admission vs. in-hospital stay.
9 Jun, 2021 | 08:20h | UTCInvited commentary: Hospitalization at Home for Patients With Acute Exacerbation of Chronic Disease—Further Evidence to Inform Practice – JAMA Network Open
Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient AND Randomized trial: Admission Avoidance Hospital at Home + Geriatric Assessment led to similar outcomes compared to hospital admission for older persons AND Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk.
China to offer COVID-19 vaccine to children as young as three.
9 Jun, 2021 | 08:26h | UTCChina to offer COVID-19 vaccine to children as young as three – MedicalXpress
See also: Sinovac says its vaccine is safe for children as young as 3 – Associated Press
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
9 Jun, 2021 | 08:12h | UTCOriginal Guideline: WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment – Drug-Resistant Tuberculosis Treatment
Commentary on Twitter
???@ERSpublications
WHO guidelines on the treatment of drug-resistant TB contain the latest recommendations on shorter or longer all oral treatment regimens for patients with drug-resistant TB, including the medicines to be used& supportive measures https://t.co/qeeftVYdYN pic.twitter.com/4NKNNjz3Gh— Antibiotic Steward ???Bassam Ghanem (@ABsteward) June 8, 2021
No health issues in babies whose moms got flu vaccine while pregnant.
9 Jun, 2021 | 08:17h | UTCNo health issues in babies whose moms got flu vaccine while pregnant – CIDRAP
Original study: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes – JAMA (free for a limited period)
Editorial: Realizing the Potential of Maternal Influenza Vaccination (free for a limited period)
Commentary on Twitter
Thrilled to be part of this @JAMA_current study led by @deshaynef et al. showing that influenza immunization in pregnancy doesn't increase risk of asthma or infections in newborns https://t.co/0zscKLDm7L @ICESOntario @CANImmunize @DrJeffKwong @drkarinatop @Sprague_Ann
— Eric Benchimol (@ericbenchimol) June 8, 2021
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Opinion | Scientific publishing’s new weapon for the next crisis: the rapid correction.
9 Jun, 2021 | 08:14h | UTCScientific publishing’s new weapon for the next crisis: the rapid correction – STAT
FDA approvement of Alzheimer’s drug sparks controversy among doctors.
9 Jun, 2021 | 08:18h | UTCNews release: FDA Grants Accelerated Approval for Alzheimer’s Drug – U.S. Food & Drug Administration
Commentaries: ICER Issues Statement on the FDA’s Approval of Aducanumab for Alzheimer’s Disease – Institute for Clinical and Economic Review AND Landmark Alzheimer’s Drug Approval Confounds Research Community – Nature AND FDA approves Alzheimer’s drug from Biogen, against experts’ advice – NBC News AND F.D.A. Approves Alzheimer’s Drug Despite Fierce Debate Over Whether It Works – The New York Times (a few articles per month are free) AND Alzheimer’s drug approved despite doubts about effectiveness – Science (a few articles per month are free) AND The FDA Has Approved A New Alzheimer’s Drug — Here’s Why That’s Controversial – NPR AND Opinion: Bad medicine: aducanumab is a lackluster drug with a high price tag – STAT
Current state of analgesia and sedation in the pediatric intensive care unit.
9 Jun, 2021 | 08:09h | UTC
RCT: Vaginal administration of misoprostol is superior to buccal administration of misoprostol along with a Foley catheter for induction of labor.
9 Jun, 2021 | 08:11h | UTCBuccal vs vaginal misoprostol combined with Foley catheter for cervical ripening at term (the BEGIN trial): a randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
Buccal vs vaginal misoprostol combined with Foley catheter for cervical ripening at term (the BEGIN trial): a randomized controlled trial https://t.co/O1tuXJM5lp pic.twitter.com/VOKlhWaxp7
— AJOG (@AJOG_thegray) May 15, 2021
Difficult airway management in neonates and infants: knowledge of devices and a device-oriented strategy.
9 Jun, 2021 | 08:08h | UTC