Daily Archives: June 4, 2021
Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.
4 Jun, 2021 | 10:43h | UTCCommentaries: Very high use of antibiotics in COVID-19 treatment could be reduced – University of Glasgow AND More evidence of frequent antibiotic use noted in COVID patients – CIDRAP AND Covid-19: Antimicrobial use was high during first wave despite bacterial co-infections being rare, study finds – The BMJ
Related: Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT
Commentary on Twitter (thread – click for more)
Our paper on co-infections, secondary infections & antimicrobial use in patients hospitalised with #COVID19 in UK during the 1st wave is out in @LancetMicrobe!@ISARIC1 @CCPUKstudy @CVRinfo @UofGlasgow @EdinburghUni @LivUni @imperialcollege https://t.co/QYU1B2Eyup
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— Antonia Ho (@DrToniHo) June 3, 2021
In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.
4 Jun, 2021 | 10:35h | UTCCommentary: Vitamin D may not provide protection from COVID-19 susceptibility or disease severity, study suggests – PLOS
Related: Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19. AND RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19
RCT: Prophylactic post-exposure prophylaxis with Bamlanivimab reduced the incidence of Covid-19 among residents and staff of skilled nursing and assisted living facilities.
4 Jun, 2021 | 10:40h | UTCEditorial: Bamlanivimab for Prevention of COVID-19
[Preprint] Covid-19 B.1.617.2 variant of concern (Delta) is associated with increased transmissibility compared to B.1.1.7 (Alpha) that will rapidly lead to B.1.617.2 becoming the prevailing variant in the UK.
4 Jun, 2021 | 10:36h | UTCRelated: Covid: Indian variant ‘now dominant’ in the UK – BBC
United States Unveils Global Vaccine Sharing Scheme for 80 Million Doses by End June
4 Jun, 2021 | 10:32h | UTCSee also: Statement by President Joe Biden on Global Vaccine Distribution – The White House
Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients.
4 Jun, 2021 | 10:26h | UTC
RCT: No benefit from passive leg raising during cardiopulmonary resuscitation in out-of-hospital cardiac arrest.
4 Jun, 2021 | 10:28h | UTC
Commentary on Twitter
Recently released in @Crit_Care our passive leg raising out-of-hospital cardiac arrest randomized controlled trial
Neutral results in survival and no evidence of adverse effects @eneko70 @alfredobardaji @mjimenezherrera https://t.co/dyxCJAB4bG— Youcef Azeli (@YoucefAzeli) May 25, 2021
WHO: Vaccinating kids ‘not a high priority’ amid shortage
4 Jun, 2021 | 10:31h | UTCWHO: Vaccinating kids ‘not a high priority’ amid shortage – Associated Press
Related: WHO: Wealthy nations urged to delay youth Covid vaccines, donate to solidarity scheme AND Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”. AND Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”. AND Vaccinating children before poor morally wrong, Oxford scientist says – BBC
M-A: In hypoxemic non-hypercapnic patients, early extubation followed by noninvasive ventilation can reduce the total number of days of invasive mechanical ventilation (mean difference, − 2.04 days), without effects in ICU mortality.
4 Jun, 2021 | 10:27h | UTC
ANCA-Associated Vasculitis: An Update.
4 Jun, 2021 | 10:23h | UTCANCA-Associated Vasculitis: An Update – Journal of Clinical Medicine
RCT: Among patients with ANCA-associated vasculitis without severe glomerulonephritis or alveolar hemorrhage treated with Rituximab, a reduced-dose glucocorticoids regimen (prednisolone 0.5 mg/kg/d) was noninferior to a high-dose glucocorticoid regimen (prednisolone 1 mg/kg/d) for the induction of disease remission.
4 Jun, 2021 | 10:25h | UTC
Diagnosis and management of diabetes insipidus for the internist: an update
4 Jun, 2021 | 10:22h | UTC