Daily Archives: May 10, 2021
New WHO Online Course: Initial approach to the acutely ill patient with COVID-19.
10 May, 2021 | 01:21h | UTC
WHO Infographic | How to care COVID-19 patients with mild symptoms at home: information for health care workers.
10 May, 2021 | 01:17h | UTCCOVID-19 home care bundle for health care workers – World Health Organization
Commentary on Twitter
How to care #COVID19 patients with mild symptoms at home: information for health care workershttps://t.co/r09i9k0zGl pic.twitter.com/i5ihXQrhzg
— World Health Organization (WHO) (@WHO) May 8, 2021
WHO lists Sinopharm COVID-19 vaccine for emergency use and issues interim recommendations.
10 May, 2021 | 01:19h | UTCCommentaries: WHO approves Sinopharm vaccine in potential boost to COVAX pipeline – Reuters AND WHO panel OKs emergency use of China’s Sinopharm vaccine – Associated Press AND WHO lists Sinopharm COVID-19 vaccine for emergency use – CIDRAP
Commentary on Twitter (thread – click for more)
WHO today listed the Sinopharm #COVID19 vaccine for emergency use in all countries, a prerequisite for a potential #COVAX roll-out. Interim policy recommendations were also issued for the vaccine usage.
? https://t.co/wuvNptP1LV pic.twitter.com/hm6TlpLJSy
— World Health Organization (WHO) (@WHO) May 7, 2021
Covid-19: Most people admitted to hospital after vaccination were infected before immunity could develop, research shows.
10 May, 2021 | 01:14h | UTC
Commentary on Twitter
"#Covid19: Most people admitted to hospital after vaccination were infected before immunity could develop, research" https://t.co/wi30LkafC7
"…highlighting the importance of maintaining social distancing & understanding that immunity develops over time…"#ScienceUpFirst!
— Timothy Caulfield (@CaulfieldTim) May 7, 2021
Opinion | Aerosol generating procedures: are they of relevance for transmission of SARS-CoV-2?
10 May, 2021 | 01:16h | UTC
Commentary on Twitter
"The term AGP has neither face validity nor construct validity. We should focus on the risk in plain sight: caring for patients with COVID-19 who are coughing."
New paper arguing to bury the term 'aerosol generating procedure'.
Great work from Bristol team. pic.twitter.com/fKTFRKcmy1
— Trisha Greenhalgh ? #CovidIsAirborne (@trishgreenhalgh) May 7, 2021
CDC website now emphasizes coronavirus spreads in the air.
10 May, 2021 | 01:11h | UTCCDC website now emphasizes coronavirus spreads in the air – CNN
Commentary on Twitter
1/ A radical shift today by @CDCgov, finally aligning itself with science on the modes of transmission, and throwing away the 1910 error of considering "close contact" a mode of transmission!https://t.co/5pP25OTY5d
— Jose-Luis Jimenez (@jljcolorado) May 8, 2021
Here’s what’s known about the coronavirus variants.
10 May, 2021 | 01:12h | UTCHere’s what’s known about the coronavirus variants – CNN
Viewpoint | Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized?
10 May, 2021 | 01:09h | UTCPrecision Medicine for COVID-19: Phenotype Anarchy or Promise Realized? – JAMA
Editorial: India’s COVID-19 emergency.
10 May, 2021 | 01:09h | UTCIndia’s COVID-19 emergency – The Lancet
Related: Editorial: ovid-19: India’s crisis is everyone’s crisis – The BMJ AND India’s worsening Covid crisis could spiral into a problem for the world – CNBC AND Is India’s coronavirus death ‘paradox’ vanishing? – Science
M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.
10 May, 2021 | 01:00h | UTCCommentaries: Fish oil supplements linked with heart rhythm disorder – European Society of Cardiology AND Could High-Dose Fish Oil Raise Odds for A-Fib in Heart Patients? – HealthDay
Commentary on Twitter
Our latest work showing an increased risk of AFib with O3FA supplementation.
Omega-3 fatty acids supplementation and risk of atrial fibrillation: an updated meta-analysis of randomized controlled trials https://t.co/7Z8CAuDHNr @totocarbone @gbiondizoccai @MarcoDelBuono3 pic.twitter.com/A5m77y5xTE
— Dave Dixon, PharmD (@DaveDixonPharmD) April 29, 2021
Perspective | Flu Has Disappeared Worldwide during the COVID Pandemic: “The public health measures that slow the spread of the novel coronavirus work really well on influenza”.
10 May, 2021 | 01:08h | UTCFlu Has Disappeared Worldwide during the COVID Pandemic – Scientific American
A restrictive fluid management strategy shows promise for acute kidney injury in a pilot randomized controlled trial.
10 May, 2021 | 00:57h | UTC
Commentary on Twitter
REVERSE-AKI restrictive fluid management vs usual care among critically ill pts with #AKI (proper initial fluid resus), multicenter feasibility RCT:
restriction? ⬇️cumulative fluid balance#RRT ➡️13% vs 30%
diuretics ↔️
usual care? ⬆️adverse events#FOAMcc https://t.co/JdKDo1XeIf pic.twitter.com/P1sOCHjkCS— Intens Care Med (@yourICM) May 7, 2021
[#ACC21 – not published yet] 1 in 5 adults with high blood pressure also take a medicine that could be elevating their blood pressure.
10 May, 2021 | 00:58h | UTCHave high blood pressure? You may want to check your meds – American College of Cardiology
Commentary: Are You Taking a Med That’s Raising Your Blood Pressure? – HealthDay
Drugs tested in low- and middle-income countries are often not available for use in these countries even after a few years.
10 May, 2021 | 00:54h | UTC
Commentary on Twitter
Sharing benefits and burdens of clinical research? Or not…
Of 70 countries enrolling pts. for new-drug trials, 7% got market access to the drugs they helped test <1 year after FDA approval, 31% did so at 5 years. Lowest access in Africa & Middle East?https://t.co/p2uCP43hOG pic.twitter.com/cqsucO1kxP
— Søren M Bentzen (@SorenBentzen) May 6, 2021
Review: Colchicine and the heart.
10 May, 2021 | 00:56h | UTCColchicine and the heart – European Heart Journal
Related meta-analysis: Colchicine administration for percutaneous coronary intervention
Related randomized trials: Colchicine in patients with chronic coronary disease (study and commentaries) AND Low-Dose Colchicine Improves Outcomes after Myocardial Infarction (study and commentaries) AND Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT) (study and commentary)
Commentary on Twitter
Colchicine and the heart
? Great review summarizing the evidence of colchicine in CV diseases @ESC_Journals https://t.co/edDw5zID5j pic.twitter.com/NqQGgdDwlX
— Enrique Santas (@SantasEnrique) May 7, 2021
RCT: Inclusion of 18F-fluciclovine-PET/CT imaging to guide postprostatectomy salvage radiotherapy in patients with prostate cancer may improve survival free from biochemical recurrence or persistence.
10 May, 2021 | 00:46h | UTC18F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial – The Lancet (link to abstract – $ for full-text)
RCT: Efficacy and safety of voclosporin for lupus nephritis – voclosporin + MMF + low dose corticosteroids achieved complete renal response at week 52 more often than MMF + low dose corticosteroids alone (41% vs. 23%).
10 May, 2021 | 00:48h | UTCEfficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
RCT: Community pharmacies provision of a progestogen-only pill + invitation to a sexual and reproductive health clinic as a bridging contraception intervention for women receiving emergency contraception is associated with increased subsequent use of long-term effective contraception.
10 May, 2021 | 00:45h | UTC
Case-control study shows an increased risk of colorectal cancer in first degree relatives of patients with colorectal polyps.
10 May, 2021 | 00:50h | UTCCommentaries: Intestinal polyps in close relatives can increase risk of colorectal cancer – Karolinska Institutet AND Relatives’ Colonoscopy Results Could Affect Your Colon Cancer Risk – HealthDay
Commentary on Twitter
After adjusting for family history of colorectal cancer, siblings and children of patients with colorectal polyps were found to be at increased risk of colorectal cancer in this study #BMJResearch https://t.co/E30VDw3PqT
— The BMJ (@bmj_latest) May 9, 2021
Population-based cohort study suggests increased survival after breast conservation surgery + radiotherapy compared to mastectomy with or without radiotherapy in women with breast cancer.
10 May, 2021 | 00:42h | UTC
Commentary on Twitter
Women receiving breast-conserving surgery for #breastcancer fare better than those who take away the whole breast says a new study taking into account comorbidities and socioeconomic background. Superior survival rates support less extensive surgery https://t.co/JEXasP56Di
— JAMA Surgery (@JAMASurgery) May 5, 2021
German National Guideline on the management of pilonidal disease.
10 May, 2021 | 00:40h | UTC
WHO calls for pharma transparency in clinical trial data reporting.
10 May, 2021 | 00:39h | UTCWHO Calls For Pharma Transparency In Clinical Trial Data Reporting – Health Policy Watch
WHO Statement: Joint Statement on transparency and data integrity International Coalition of Medicines Regulatory Authorities (ICMRA) and WHO
Commentary on Twitter
Wide and open access to clinical data for new medicines and vaccines will help build trust and the expand access @WHO @US_FDA @EMA_News @CDSCO_INDIA_INF @MoHFW_INDIA @ICMRDELHI @JeremyFarrar @Chikwe_I @jarottingen @pahowho https://t.co/1OACILbdh6
— Soumya Swaminathan (@doctorsoumya) May 7, 2021