Daily Archives: April 18, 2021
Ten scientific reasons in support of airborne transmission of SARS-CoV-2
18 Apr, 2021 | 21:51h | UTCTen scientific reasons in support of airborne transmission of SARS-CoV-2 – The Lancet
Animated Videos: Aerosols and making spaces safe – University of Oxford
Commentary on Twitter (thread – click for more)
Just out in @TheLancet what experts have said for a year
SARS-CoV2 spreads PRIMARILY via airborne route
Failure to act on this has hampered efforts to prevent spread of COVID
Thank you @trishgreenhalgh @linseymarr @kprather88 @j_g_allen, others who stuck to the evidence https://t.co/uuJcUIKWHE
— Ashish K. Jha, MD, MPH (@ashishkjha) April 16, 2021
2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult
18 Apr, 2021 | 21:24h | UTC
Commentary on Twitter
Check out the latest @SCC_CCS Guideline for the Management of Dyslipidemia for the Prevention of #Cardiovascular Disease!! https://t.co/ZKC7DrMIOq #HotOffThePress @ThanassoulisMD @ArdenBarry @DrNatDayan @RuthMcPherson12 @HeartDocRx @SCC_CCS_KT @SCC_CCS_CEO @SCC_CCS_Trainee pic.twitter.com/LZFbXNjztP
— CJC (@CJC_JCC) March 27, 2021
RCT: No benefit from second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis
18 Apr, 2021 | 21:21h | UTCSecond intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
RCT: Ravidasvir plus sofosbuvir are effective and well tolerated in patients with chronic HCV infection, with potential as an affordable treatment for these patients
18 Apr, 2021 | 21:19h | UTC
Commentary on Twitter
Trial results of new affordable #hepatitisC treatment showing 97% cure rate now published in @LancetGastroHep!
Ravidasvir + sofosbuvir has the potential to provide an additional affordable, simple, and efficacious #publichealth tool to eliminate HCV.
➡️https://t.co/Oo1ZHQnyn6 pic.twitter.com/FcFntfYMSC
— Drugs for Neglected Diseases initiative (@DNDi) April 16, 2021
ESC Consensus Document: Personalized exercise prescription in the prevention and treatment of arterial hypertension
18 Apr, 2021 | 21:22h | UTCNews release: How to prevent and treat high blood pressure with exercise – European Society of Cardiology
Therapies for Clinically Localized Prostate Cancer: A Comparative Effectiveness Review
18 Apr, 2021 | 21:16h | UTC
M-A: Nonantibiotic Strategies for the Prevention of Infectious Complications following Prostate Biopsy
18 Apr, 2021 | 21:14h | UTC
Viewpoint | Implementing Measurement Science for Electronic Health Record Use – “Clinicians trained in patient care are locked into hours of screen time to complete mandatory clerical and documentation tasks, often unrelated to the quality of the care”
18 Apr, 2021 | 21:09h | UTCImplementing Measurement Science for Electronic Health Record Use – JAMA (free for a limited period)
Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (resources on the subject) AND Study: Association Between Perceived Electronic Health Record Usability and Professional Burnout (study and commentaries) AND The future of electronic health records – Nature
Commentaries on Twitter
To optimize #EHR design, implementation, and regulation, EHR use measures must be developed that are trustworthy, clinically important, scientifically sound, transparent, and feasible for implementation.
A recent paper by @JAMA_current @JAMANetwork https://t.co/IN3ZxcON9m pic.twitter.com/kOVQGI1OGl
— Eugenio Santoro (@eugeniosantoro) April 11, 2021
"Drawing attention to the EHR user experience with empirical measurements could add visibility and transparency to what is happening—the hours wasted and the risks incurred—that could stimulate usability improvements." https://t.co/WCzuo288Bp
— Janos Kalman (@kalman_jl) April 9, 2021
RCT: Better continence after 3 months with robotic-assisted compared with laparoscopic radical prostatectomy
18 Apr, 2021 | 21:11h | UTCRobotic-assisted Versus Laparoscopic Surgery: Outcomes from the First Multicentre, Randomised, Patient-blinded Controlled Trial in Radical Prostatectomy (LAP-01) – European Urology (link to abstract – $ for full-text)
Commentary on Twitter
Robotic-assisted Versus Laparoscopic Surgery: Outcomes from the First Multicentre, Randomised, Patient-blinded Controlled Trial in Radical Prostatectomy (LAP-01)https://t.co/YenifaBnfe@doguteber @Hohenfellner pic.twitter.com/kfpQc1u0xf
— European Urology (@EUplatinum) February 11, 2021
China’s Sinovac COVID-19 vaccine 67% effective in preventing symptomatic infection, 85% effective in preventing hospitalizations and 80% effective in preventing deaths – Chile govt report
18 Apr, 2021 | 21:45h | UTC
Commentary on Twitter (thread – click for more)
Sinovac's CoronaVac in Chile: for Feb-Mar, during major outbreak. Data from National Health Fund, comparisons adjusted for age, gender, region, income, nationality. Fully vaccinated after 14 days was effective; 1 dose wasn't …1/nhttps://t.co/lNqGqTy7mv (TY for all the alerts!) pic.twitter.com/q1Fk2D3aek
— Hilda Bastian, PhD (@hildabast) April 16, 2021
A guideline to limit indoor airborne transmission of COVID-19
18 Apr, 2021 | 21:47h | UTC
Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission
18 Apr, 2021 | 21:49h | UTCIndoor Air Changes and Potential Implications for SARS-CoV-2 Transmission – JAMA
Commentary on Twitter (thread – click for more)
In this new piece in @JAMA_current, I teamed up w/ colleague @AndrewMIbrahim to argue that
1) evidence for airborne spread is strong
2) enhanced ventilation/filtration is needed
3) 4-6 air changes per hour should be target for small volume spacesTHREADhttps://t.co/bvdZkyy03j
— Joseph Allen (@j_g_allen) April 16, 2021
Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination
18 Apr, 2021 | 21:43h | UTCCommentaries: Researchers Offer Algorithm for Managing Thrombosis and Thrombocytopenia After COVID-19 Vaccination – NEJM Journal Watch AND Blood Clots After COVID-19 Vaccination Linked to Immune Response: UK Report – TCTMD AND People with rare blood clots after a COVID-19 jab share an uncommon immune response – ScienceNews
Editorial: SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – “The very low prevalence of this complication of vaccination, however severe, relative to the benefits of preventing Covid-19 must be emphasized”
18 Apr, 2021 | 21:42h | UTCSARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine
COVID vaccines and blood clots: five key questions
18 Apr, 2021 | 21:40h | UTCCOVID vaccines and blood clots: five key questions – Nature
See also (podcast): Coronapod: could COVID vaccines cause blood clots? Here’s what the science says – Nature
Study shows past COVID-19 infection doesn’t fully protect young people against reinfection
18 Apr, 2021 | 21:35h | UTCOriginal study: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study – The Lancet Respiratory Medicine
Commentary on Twitter
Risk of covid reinfection in a prospective study of >3,000 Marine recruits
Prior covid: 82% reduced compared w/ no prior covid (+ when reinfections occurred, much less viral loads)
Protection correlated w/ higher spike IgG antibody levels https://t.co/7Jl154lwDX @LancetRespirMed pic.twitter.com/xKVLKm8AA6— Eric Topol (@EricTopol) April 15, 2021
WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1
18 Apr, 2021 | 21:32h | UTC
Study: Double masking improves protection from Covid-19 mostly by eliminating any gaps or poor-fitting areas of a mask
18 Apr, 2021 | 21:37h | UTCFitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic – JAMA Internal Medicine
Commentaries: Fit matters most when double masking to protect yourself from COVID-19 – University of North Carolina Health Care AND Check your fit on that double mask if you want it to work against Covid, study says – CNN
Study Commentary | What if the EHR Age-Adjusts D-dimer for You?
18 Apr, 2021 | 21:04h | UTCWhat if the EHR Age-Adjusts D-dimer for You? – Journal Feed
Original study: Multi-center implementation of automated age-adjusted D-dimer results reduces unnecessary PE imaging – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Study suggests treatment not always needed to prevent vision loss in patients with elevated eye pressure
18 Apr, 2021 | 21:01h | UTCOriginal study: Assessment of Cumulative Incidence and Severity of Primary Open-Angle Glaucoma Among Participants in the Ocular Hypertension Treatment Study After 20 Years of Follow-up – JAMA Ophthalmology (free for a limited period)
Commentary on Twitter
Only 25% of the OHTS participants developed visual field loss over 20 years of follow-up https://t.co/2DV1gr0cbM
— JAMAOphthalmology (@JAMAOphth) April 15, 2021
Liabilities with artificial intelligence: 4 things future radiologists kneed to know
18 Apr, 2021 | 21:02h | UTCClinical applications of AI in MSK imaging: a liability perspective – Skeletal Radiology
Commentaries: 4 Must-Knows about Future Radiologist Liabilities with AI – Diagnostic Imaging AND Who will be liable in the coming AI age? 4 things for radiologists to know – HealthImaging
Case report: Energy drink-induced cardiomyopathy
18 Apr, 2021 | 21:00h | UTCEnergy drink-induced cardiomyopathy – BMJ Case Reports
Commentaries: Student’s heart failure linked to ‘excessive’ energy drinks – BBC AND Heavy energy drink consumption linked to heart failure in a young man – BMJ