Daily Archives: March 21, 2021
Study: More than half of antibiotics prescribed in US hospitals were not consistent with recommended prescribing practices
21 Mar, 2021 | 21:44h | UTCAssessment of the Appropriateness of Antimicrobial Use in US Hospitals
Commentary: New findings spur call to reduce improper antibiotic use in hospitals – CIDRAP
Commentary on Twitter
Newly published CDC data estimates that more than half of antibiotics prescribed in U.S. hospitals for selected prescribing events were not consistent with recommended prescribing practices. https://t.co/oZXNX26UiD pic.twitter.com/hUOrRxsPJG
— CDC Emerging Infections (@CDC_NCEZID) March 18, 2021
M-A: Most patients with allergy to Penicillin can be given Cefazolin
21 Mar, 2021 | 21:41h | UTC
Commentary on Twitter (thread – click for more)
1/Returning to my first love #antibioticallergy #penicillin allergy with @PharmerMeg to announce to #IDtwitter #MedTwitter that if you see a patient with a "penicillin allergy" history, the likelihood of them having a reaction to cefazolin/ancef is 0.7%. https://t.co/czVX6wik2Y
— Kimberly Blumenthal, MD, MSc (@KimberlyBlumen1) March 17, 2021
Podcast: Things We Do For No Reason in Pediatrics #2
21 Mar, 2021 | 21:37h | UTCThings We Do For No Reason in Pediatrics #2 – Cribsiders
Related episode: Things We Do For No Reason in Pediatrics
Long-term outcomes of patients undergoing the Ross procedure
21 Mar, 2021 | 21:42h | UTCCommentaries: Ross Procedure Done Well Holds Up Over Time – TCTMD AND Long-Term Outcomes of the Ross Procedure – American College of Cardiology
Short review: Caring for the patient with catatonia
21 Mar, 2021 | 21:39h | UTCCaring for the Patient With Catatonia – JAMA Psychiatry
Expert consensus statements for the management of COVID-19-related acute respiratory failure
21 Mar, 2021 | 22:05h | UTC
Commentary on Twitter
?Expert consensus statements for the management of ?? COVID-19-related acute respiratory failure using a Delphi method.
?????https://t.co/ujt8669VAb pic.twitter.com/AlT0ZkdKSc— RECAT??⚕️???⚕️ (@LeslieMegom) March 17, 2021
Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition
21 Mar, 2021 | 21:34h | UTCTwo Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition – New England Journal of Medicine (link to abstract – $ for full-text)
Bioethics | “Nazi anatomical drawings are donated in effort to address ethical quandary — and spotlight a dark history”
21 Mar, 2021 | 21:38h | UTCRelated: ”The surgeon had a dilemma only a Nazi medical text could resolve. Was it ethical to use it?” – STAT
RCT: Pegcetacoplan vs. Eculizumab in Paroxysmal Nocturnal Hemoglobinuria
21 Mar, 2021 | 21:32h | UTC
Researchers identify head impact rates in four major high school sports
21 Mar, 2021 | 21:30h | UTCNews release: Researchers Identify Head Impact Rates in Four Major High School Sports – Children’s Hospital of Philadelphia
Original study: Sport- and Gender-Based Differences in Head Impact Exposure and Mechanism in High School Sports – Orthopaedic Journal of Sports Medicine
Commentary on Twitter
Excited to share our publication in @OJSM_SportsMed with @kristyarb and @drtinamaster! Male and female high school soccer had the highest head impact rate across four sports. Male teams also had higher impact rates than female teams of the same sport.https://t.co/eMOL925s04 https://t.co/elutojRfwJ
— Colin Huber (@Colin_M_Huber) March 18, 2021
Cohort study: Preschoolers’ extensive electronic media use linked to emotional/behavioral issues
21 Mar, 2021 | 21:29h | UTCOriginal Study: High-dose electronic media use in five-year-olds and its association with their psychosocial symptoms: a cohort study – BMJ Open
Commentaries: Preschoolers’ extensive electronic media use linked to emotional/behavioural issues – British Medical Journal AND Expert reaction to observational study on electronic media use in 5 year olds and psychosocial symptoms – Science Media Centre AND Does Too Much ‘Screen Time’ Have Your Preschooler Acting Out? – HealthDay
Commentary on Twitter
Preschoolers’ extensive use of electronic media, including game consoles, mobile phones, and tablets, is linked to a heightened risk of emotional and behavioural problems by the age of 5, finds new research in @BMJ_Open https://t.co/RIheqGDneF @EJPaavon pic.twitter.com/Ax6cnW1iZ4
— BMJ (@bmj_company) March 18, 2021
Infection and mRNA vaccine-induced immunity may be retained against SARS-CoV-2 variant B.1.1.7
21 Mar, 2021 | 22:04h | UTCNeutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination – JAMA
SARS-CoV-2 variants B.1.351 and P.1 can escape from therapeutic antibodies and evade antibodies induced by infection or mRNA vaccination
21 Mar, 2021 | 22:02h | UTCSARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies – Cell
CDC Guidance for schools says students can now stay 3 feet apart, rather than 6
21 Mar, 2021 | 22:07h | UTCCommentaries: CDC Says Schools Can Now Space Students 3 Feet Apart, Rather Than 6 – NPR AND CDC updates COVID school guidance, OKs 3-feet distancing – CIDRAP
Related: Cohort study: Effectiveness of three vs. six feet of physical distancing for controlling spread of COVID-19 among primary and secondary students and staff (study and commentary)
Commentaries on Twitter
CDC: Children in elementary schools don't need to be kept 6-feet apart. In a major policy revision, federal health officials said only 3 feet of distance is required between young children in classrooms https://t.co/UBvES1T6ps
— delthia ricks ? (@DelthiaRicks) March 19, 2021
Very happy CDC now recommending 3 feet spacing in schools: "The change is momentous .because many schools.. operate on part-time or hybrid schedules in order to reduce class sizes. A 3-foot rule would allow many more schools to open in person, full time."https://t.co/wR88jdUBgM
— Monica Gandhi MD, MPH (@MonicaGandhi9) March 19, 2021
[Preprint] Oxford/AstraZeneca and Pfizer/BioNTech vaccines probably can still neutralize P.1 strain of SARS-CoV-2, but at lower levels
21 Mar, 2021 | 21:55h | UTCAntibody evasion by the Brazilian P.1 strain of SARS-CoV-2 – bioRxiv
Commentary: Existing COVID vaccines may protect against Brazilian variant – Oxford study – Reuters
B.1.351 strain of SARS-CoV-2 neutralization titer reduced 8- to 9-fold for Pfizer and AstraZeneca vaccinees. Convalescent plasma and therapeutic antibodies were less effective against this variant as well.
21 Mar, 2021 | 21:52h | UTCEvidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera – Cell
Bioethics | “Europe’s Vaccine Ethics Call: Do No Harm and Let More Die?”
21 Mar, 2021 | 21:50h | UTCEurope’s Vaccine Ethics Call: Do No Harm and Let More Die? – The New York Times (free registration may be required)
Related opinion: Covid-19 vaccine adverse events: balancing monitoring with confidence in vaccines – The BMJ Opinion
See also: European Medicines Agency finds AstraZeneca vaccine is safe and benefits outweigh the risks (Statement and commentaries) AND Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine – World Health Organization AND Update on the safety of COVID-19 Vaccine AstraZeneca (statement and commentaries)
Commentary on Twitter
Many bioethicists have a problem with how Europe halted use of the AstraZeneca vaccine. Keeping the vaccine available would have allowed people “to consensually protect themselves from a big risk by taking a very small one.” https://t.co/qctELhfFGI
— NYT Health (@NYTHealth) March 20, 2021
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review
21 Mar, 2021 | 21:49h | UTC
Commentary on Twitter
@JACCJournals: We share a systematic summary of #anticcogulation,#antiplatelet, and #fibrinolysis #RCTs in #COVID19. Amazing work by @AzitaTalasaz and a stellar multidisciplinary team! Figs illustrate areas where we’ll have evidence, & the gaps. Link: https://t.co/t4ksxwjAze pic.twitter.com/0Th3OZBXOY
— Behnood Bikdeli (@bbikdeli) March 16, 2021
Modeling Study: Vaccination alone is unlikely to contain COVID-19 infections in UK
21 Mar, 2021 | 21:46h | UTCCommentaries: Risking further COVID-19 waves despite vaccination – The Lancet Infectious Diseases AND Vaccination alone is unlikely to contain COVID-19 infections in UK – The Lancet
Commentary on Twitter
Vaccination alone is unlikely to contain #COVID19 infections in UK, suggests modelling study in @TheLancetInfDis—gradual release of control measures, high vaccine uptake, and high efficacy vaccine essential to minimise future waves. https://t.co/zpbPsYVHS2 pic.twitter.com/v47v6ux4r6
— The Lancet (@TheLancet) March 19, 2021
Clinician Guide to COVID-19 diagnostics in children
21 Mar, 2021 | 21:48h | UTCClinician guide to COVID-19 diagnostics – ADC Education & Practice