Daily Archives: March 11, 2021
Pragmatic RCT: No difference in outcomes from different gestational diabetes screening methods
11 Mar, 2021 | 08:12h | UTCA Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: One-Step Screening for Gestational Diabetes Increases Diagnoses — But Doesn’t Improve Outcomes – NEJM Journal Watch AND How Do Screening Methods for Gestational Diabetes Compare? – AJMC AND Different gestational diabetes screening methods cause no difference for complications – 2 Minute Medicine
Consensus Statement: Preoperative management of endocrine, hormonal, and urologic medications
11 Mar, 2021 | 08:04h | UTC
AHA Scientific Statement | Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses
11 Mar, 2021 | 08:07h | UTC
M-A: Sequential combination of pharmacotherapy and psychotherapy in major depressive disorder
11 Mar, 2021 | 08:00h | UTCCommentary: How To Prevent A Relapse Of Clinical Depression – Forbes
M-A: Little benefit from antidepressants for low back pain
11 Mar, 2021 | 08:02h | UTCCommentary: Antidepressants provide no important benefits for managing low back pain – News Medical
Related meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis (study and commentaries)
Comparison of palliative care delivery in the last year of life between adults with terminal noncancer illness or cancer
11 Mar, 2021 | 07:55h | UTCCommentary: People with dementia receive fewer palliative referrals than those with cancer: study – McNight’s
Commentary on Twitter
Cohort study finds differences in #PalliativeCare for cancer vs noncancer patients: Earlier initiation/Multiple settings/Shared care. Need to improve equitable access to care across all settings @CanadianHPCAssn @AAHPM @HQOntario @ICESOntario @SinaiHealth https://t.co/b7i4z8zokq
— JAMA Network Open (@JAMANetworkOpen) March 5, 2021
Cohort study: Association of Ibuprofen prescription with acute kidney injury among hospitalized children
11 Mar, 2021 | 07:57h | UTC
Commentary on Twitter
Cohort study finds ibuprofen was widely used and associated with an increased risk of HA-AKI in hospitalized children. Rational prescribing of ibuprofen is an important strategy to reduce the burden of HA-AKI in children. https://t.co/jgQD4ELXxN
— JAMA Network Open (@JAMANetworkOpen) March 5, 2021
Position Statement: The Role of Pharmacogenomics in Contemporary Cardiovascular Therapy
11 Mar, 2021 | 07:53h | UTC
[Press release – not published yet] Monoclonal antibodies reduced hospitalizations and death in Phase 3 trial for early COVID-19
11 Mar, 2021 | 08:41h | UTCPress release: Lilly’s bamlanivimab and etesevimab together reduced hospitalizations and death in Phase 3 trial for early COVID-19
Commentary: Eli Lilly’s combo therapy for COVID-19 cuts serious illness and death in large study – Reuters
Death rate 64% higher with B117 COVID variant, study finds
11 Mar, 2021 | 08:38h | UTCDeath rate 64% higher with B117 COVID variant, study finds – CIDRAP
News release: Variant B.1.1.7 of COVID-19 associated with a significantly higher mortality rate, research shows – University of Bristol
Original Study: Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study – The BMJ
Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk
11 Mar, 2021 | 08:35h | UTCOriginal study: Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study – Anaesthesia
Commentary on Twitter
Reported by > 100 news organisations and > 200k Twitter impressions in just a few hours!
Here is the new @CovidSurg infographic! Time to establish timing of surgery guidelines?@aneelbhangu @dnepo @JoanaffSimoes #FOAMed
?https://t.co/mRnV7U6u1w pic.twitter.com/BmKlxf9ZIK
— ??????????? (@Anaes_Journal) March 10, 2021
[Preprint] RECOVERY trial: Convalescent plasma does not improve outcomes in patients admitted to hospital with COVID-19
11 Mar, 2021 | 08:43h | UTC
Commentary on Twitter (thread – click for more)
RECOVERY Pre-print:
Convalescent plasma does not improve survival in patients hospitalised with COVID-19 in this randomised controlled trial involving 11,558 patients:https://t.co/36YZwJNY3Q pic.twitter.com/sKR095n1PC
— Martin Landray (@MartinLandray) March 10, 2021
State of the Art Review | Severe covid-19 pneumonia: pathogenesis and clinical management
11 Mar, 2021 | 08:37h | UTCSevere covid-19 pneumonia: pathogenesis and clinical management – The BMJ
Clinical Decisions | Doctor, How Long Should I Isolate?
11 Mar, 2021 | 08:21h | UTCDoctor, How Long Should I Isolate? – New England Journal of Medicine
Study: Children and young people remain at low risk of COVID-19 mortality
11 Mar, 2021 | 08:28h | UTC
Attributes and predictors of long COVID
11 Mar, 2021 | 08:25h | UTCAttributes and predictors of long COVID – Nature
Commentary on Twitter
Attributes and predictors of long COVID (fatigue, headache, dyspnea and anosmia) from 4182 incident cases.
– 13.3% symptoms ≥4 wks
– 4.5% for ≥8 wks
– 2.3% for ≥12 wksBeing older, female, incr. BMI, # symptoms all appeared to predict long COVID https://t.co/xSdNtLQO4V
— Andrew Morris (@ASPphysician) March 10, 2021
Audio Interview: The implications of changes in the structural biology of SARS-CoV-2
11 Mar, 2021 | 08:20h | UTC
More data suggesting a single dose of SARS-CoV-2 mRNA vaccine may be enough in seropositive individuals
11 Mar, 2021 | 08:18h | UTCRelated: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary) AND Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA