Daily Archives: February 24, 2021
Sepsis treatment: Another trial shows no benefit from the combination of Vitamin C, Thiamine, and Hydrocortisone
24 Feb, 2021 | 02:25h | UTCEffect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Hydrocortisone, Vitamin C, and Thiamine for Treatment of Sepsis: Making Evidence Matter
Related: The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis (study and commentaries)
Commentary on Twitter
VICTAS trial now in @JAMA_current. Is this the final nail in the coffin for HAT in sepsis? https://t.co/kDdmnIdC6s
— UGAC3 (@ugac3) February 23, 2021
USPSTF Draft Statement: Aspirin use to prevent morbidity and mortality from preeclampsia
24 Feb, 2021 | 02:27h | UTC
Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone
24 Feb, 2021 | 02:16h | UTCCommentaries: Amoxicillin-clavulanate safe and effective compared with metronidazole-with-fluoroquinolone for diverticulitis – American College of Physicians AND Study supports fluoroquinolone-sparing treatment for diverticulitis – CIDRAP
Review: Diagnosis and Treatment of Multiple Sclerosis
24 Feb, 2021 | 02:23h | UTCDiagnosis and Treatment of Multiple Sclerosis: A Review – JAMA
Podcast: Diagnosis and Treatment of Multiple Sclerosis—A Review
KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease
24 Feb, 2021 | 02:21h | UTC
Commentary on Twitter (thread – Click for more)
The 2021 KDIGO guideline covers optimal BP targets in patients with CKD, proper BP measurement, lifestyle interventions, antihypertensive medications, and issues specific to management in kidney transplant recipients and children. https://t.co/OXfhCbBQS9
— Kathryn Foti (@fotikat) February 23, 2021
SR: Metformin has modest efficacy for children with obesity
24 Feb, 2021 | 02:08h | UTCEfficacy and Safety of Metformin for Obesity: A Systematic Review – Pediatrics (link to abstract – $ for full-text)
Commentary: Metformin Underwhelms in Pediatric Obesity – Physician’s Weekly
Physical Activity: what’s the latest guidance?
24 Feb, 2021 | 02:19h | UTCPhysical Activity: what’s the latest guidance? – Evidently Cochrane
See also: New WHO guidelines on physical activity and sedentary behavior – Every move counts towards better health (Guideline and commentaries)
ASCO Guideline: Management of dyspnea in advanced cancer
24 Feb, 2021 | 02:10h | UTCManagement of Dyspnea in Advanced Cancer: ASCO Guideline – Journal of Clinical Oncology
Commentary on Twitter (thread – click for more)
1/ How can we better manage dyspnea in people with advanced cancer?
Wonderful to see this new @ASCO Guideline out.
Led by Drs. @DrDavidHui and @campbell_meg #supponc #pallonc
Full text: https://t.co/qbdhzbibKw pic.twitter.com/f2Qf6GswvK
— Arjun Gupta (@guptaarjun90) February 23, 2021
Testing strategies for diagnosing tuberculosis in young children
24 Feb, 2021 | 02:05h | UTCSensitive and Feasible Specimen Collection and Testing Strategies for Diagnosing Tuberculosis in Young Children – JAMA Pediatrics (free for a limited period)
Editorial: Diagnosing Childhood Tuberculosis: A Small Step Forward (free for a limited period)
Commentary: Diagnosing Pediatric TB in the Resource-Limited Areas – Physician’s Weekly
Deep learning algorithm detects universal trauma on pelvic radiographs
24 Feb, 2021 | 02:03h | UTCCommentary: AI algorithm accurately detects trauma on pelvic radiographs – AuntMinnie
Commentary on Twitter
#artificialintelligence #radiology #orthopaedics
Researchers from Taiwan and US have now developed
an AI model which can detect pelvic and femur injuries on pelvic XRays on a comparable performance with radiologists and orthopaedic surgeons: https://t.co/Ce2WUAuOvq— Sandeep Reddy (@docsunny100) February 22, 2021
Medication review interventions to reduce hospital readmissions in older people
24 Feb, 2021 | 02:14h | UTC
Commentary on Twitter
A medication review in combination with medication reconciliation, patient education, professional education and transitional care is associated with a decreased risk of hospital readmissions. #geriatrics https://t.co/nAeHF82dlm pic.twitter.com/50lEVVeQwn
— JAGS (@AGSJournal) February 16, 2021
Why are COVID-19 case numbers dropping?
24 Feb, 2021 | 02:59h | UTCWhy Are COVID-19 Case Numbers Dropping? – HIV and ID Observations
Study: Patients with severe COVID-19 might shed viable virus during prolonged periods of up to 4 weeks
24 Feb, 2021 | 02:56h | UTC
Commentary on Twitter
Different pattern of SARS-CoV-2 viability in mild cases (viral replication max 10 days) vs severe COVID-19: viable virus demonstrated up to 4 weeks even in the presence of high levels of neutralizing activityhttps://t.co/dhERkipKJ0
— Rafael Delgado (@derafaeldelgado) February 23, 2021
We’re Just Rediscovering a 19th-Century Pandemic Strategy (Ventilation)
24 Feb, 2021 | 02:58h | UTCWe’re Just Rediscovering a 19th-Century Pandemic Strategy – The Atlantic
Schools may see a burst of the common cold when they reopen, research suggests
24 Feb, 2021 | 02:51h | UTCSchools may see a burst of the common cold when they reopen, research suggests – STAT
SR: Delays and disruptions in cancer health care due to COVID-19 pandemic
24 Feb, 2021 | 02:46h | UTCCommentary: COVID-19 Pandemic Caused Delays in Cancer Care – DocWire News
Commentary on Twitter
Delays & Disruptions in #Cancer HealthCare Due to #COVID19 Pandemic – A health system Perspective:
Interruptions & disruptions in:
?77%, facility-level
?79%, supply chain
?60%, personnel availabilityFind more from @FroitbergM at:https://t.co/wGtpNW5Zrm@ASCO_pubs ?? pic.twitter.com/R3jlzAsfRG
— Dario Trapani (@darioT_) February 23, 2021
How the COVID-19 pandemic will change the future of critical care
24 Feb, 2021 | 02:49h | UTCHow the COVID-19 pandemic will change the future of critical care – Intensive Care Medicine
Commentary on Twitter
Will #COVID19 change critical care?
➡️approach to crises
➡️flexible #ICU capacity/staff & safer design
➡️efficient supply/use of PPE, devices, consumables, meds
➡️triage principles
➡️communication
➡️end‐of‐life
➡️#AI, registries, agile collaborative RCTshttps://t.co/0aWmhQxItm pic.twitter.com/qFZCi4eYwM— Intens Care Med (@yourICM) February 23, 2021
Educators may be more central drivers of Covid-19 in schools than students, CDC study finds
24 Feb, 2021 | 02:55h | UTCEducators may be more central drivers of Covid-19 in schools than students, CDC study finds – CNN
Commentary on Twitter
A new @CDCMMWR looks at #COVID19 in Georgia elementary schools. The study highlights that preventing infections in educators is an important part of stopping the spread of COVID-19 in schools. Learn more: https://t.co/UcpGxv5GYz. pic.twitter.com/2nA4YChmNO
— CDC (@CDCgov) February 22, 2021
Perspective: Is one vaccine dose enough after COVID-19 infection?
24 Feb, 2021 | 02:47h | UTCIs One Vaccine Dose Enough After COVID-19 Infection? – NIH Director’s Blog
Related: France’s health authority recommends single vaccine shot for people who have had COVID-19
Musculoskeletal involvement of COVID-19: review of imaging
24 Feb, 2021 | 02:43h | UTCMusculoskeletal involvement of COVID-19: review of imaging – Skeletal Radiology
Commentaries: Radiological images confirm ‘COVID-19 can cause the body to attack itself’ – Northwestern University AND Imaging highlights COVID-19’s MSK manifestations – AuntMinnie
Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers
24 Feb, 2021 | 02:00h | UTC
The growing evidence that the Covid-19 vaccines can reduce transmission, explained
24 Feb, 2021 | 02:40h | UTCThe growing evidence that the Covid-19 vaccines can reduce transmission, explained – Vox
Related: Can COVID vaccines stop transmission? Scientists race to find answers – Nature AND Fauci: There’s evidence COVID-19 vaccines don’t just protect you — they may stop you from spreading the virus to others, too – Insider AND [Preprint] Covid-19 vaccination associated with reduced viral load, may reduce transmission (study and commentary)