Daily Archives: February 15, 2021
Recommended childhood and adolescent immunization schedule: United States, 2021
15 Feb, 2021 | 00:58h | UTCRecommended Childhood and Adolescent Immunization Schedule: United States, 2021 – Pediatrics
Commentary: AAP Releases 2021 Child, Adolescent Immunization Schedule – HealthDay
Table 3. Recommended Child and Adolescent Immunization Schedule by Medical Indication, United States, 2021
See also: All CDC Immunization Schedulles
Corticosteroids for community acquired pneumonia, influenza and COVID-19: when, how and benefits or harm?
15 Feb, 2021 | 00:47h | UTC
ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer
15 Feb, 2021 | 00:49h | UTC
Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users
15 Feb, 2021 | 00:44h | UTC
Systematic review: Urgent‐start peritoneal dialysis vs. hemodialysis for people with chronic kidney disease
15 Feb, 2021 | 00:46h | UTC
Consensus guidelines on perioperative management of suspected malignant hyperthermia or susceptible patients
15 Feb, 2021 | 00:56h | UTC
Randomized trial: Procalcitonin to reduce long-term infection-associated adverse events in sepsis
15 Feb, 2021 | 00:43h | UTC
For patients with schizophrenia, five variables associated with everyday functioning
15 Feb, 2021 | 00:41h | UTC
Commentary on Twitter
A longitudinal study in more than 600 people with #schizophrenia documented that social and non-social cognition, avolition and positive symptoms are the main factors impacting on real-life functioning at follow-up https://t.co/xoBt5DAVfQ #ItalianNetworkforResearchonPsychoses
— JAMA Psychiatry (@JAMAPsych) February 11, 2021
CT angiography and MRI of hand vascular lesions: technical considerations and spectrum of imaging findings
15 Feb, 2021 | 00:38h | UTC
6 Red Flags: Avoid becoming invisible in the dark reading room
15 Feb, 2021 | 00:40h | UTC6 Red Flags: Avoid Becoming Invisible in the Dark Reading Room – Diagnostic Imaging
Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19
15 Feb, 2021 | 01:18h | UTCCommentaries: Preventive blood thinning drugs could reduce COVID hospital deaths – London School of Hygiene & Tropical Medicine AND Preventive blood thinning drugs linked to reduced risk of death in COVID-19 patients – The BMJ AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre AND
Commentary on Twitter
Blood thinning drugs are now linked to a reduced risk of death for COVID19 patients. Those given preventive blood thinners (prophylactic anticoagulants) within 24 hours of hospital admission for Covid were less likely to die. New report in the BMJ https://t.co/KQqQ3Zoj8B pic.twitter.com/6wJj8mEucw
— delthia ricks ? (@DelthiaRicks) February 12, 2021
Take whatever COVID vaccine you can get. All of them stop death and hospitalization
15 Feb, 2021 | 01:17h | UTCTake whatever COVID vaccine you can get. All of them stop death and hospitalization – USA Today
“All seven COVID-19 vaccines that have completed large efficacy trials — Pfizer, Moderna, Johnson & Johnson, Novavax, AstraZeneca, Sputnik V and Sinovac — appear to be 100% effective for serious complications. Not one vaccinated person has gotten sick enough to require hospitalization. Not a single vaccinated person has died of COVID-19.”
Small RCT: No effect from Zinc and Vitamin C supplementation among ambulatory patients with SARS-CoV-2 infection
15 Feb, 2021 | 01:20h | UTCCommentaries: Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds – CNN AND Supplements for the Treatment of Mild COVID-19—Challenging Health Beliefs With Science From A to Z – JAMA Network Open AND Zinc, vitamin C show no effect for COVID-19 in small study – CIDRAP AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre
Commentary on Twitter
RCT finds high-dose zinc, ascorbic acid (vitamin C), or both, did not significantly decrease the duration of symptoms in ambulatory patients with #COVID19 vs standard of care. @DesaiMilindY @ClevelandClinic @ErinMichos @miguelcainzos23 #VisualAbstract https://t.co/ahcc2awJB8
— JAMA Network Open (@JAMANetworkOpen) February 12, 2021
Challenges in ensuring global access to COVID-19 vaccines: production, affordability, allocation, and deployment
15 Feb, 2021 | 01:14h | UTC
Commentaries on Twitter
NEW—#COVID19 vaccination potential will not be achieved without increased production, affordable pricing, global availability, & successful rollout. This Health Policy compares potential of 26 leading vaccines + vaccine confidence in 32 countries. Read https://t.co/QFeRDHutAi pic.twitter.com/rgknOgCVkg
— The Lancet (@TheLancet) February 12, 2021
The practical issues of #SARSCoV2 vaccines, a new and comprehensive review @TheLancet https://t.co/6sHsac44Ej best current summary of production, $, allocation, deployment, by @ojwouters @LSEHealthPolicy and colleagues pic.twitter.com/mMxOgkjyi0
— Eric Topol (@EricTopol) February 13, 2021
Limited transmission of COVID-19 from open schools but teachers were affected: Swedish study
15 Feb, 2021 | 01:11h | UTCOriginal Study: The effects of school closures on SARS-CoV-2 among parents and teachers – Proceedings of the National Academy of Sciences
Commentary on Twitter
New data open vs closed schools from Sweden, and particularly the risk of #SARSCoV2 infections and hospitalizations among teachers, while low, doubled in upper-secondary. Parents: 17% increasehttps://t.co/y1N02xwLfc @PNASNews by @jonasvlachos @helenasvaleryd @UU_University
— Eric Topol (@EricTopol) February 11, 2021
Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US
15 Feb, 2021 | 01:13h | UTCAuthor interview: COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions – JAMA
Commentary on Twitter
More than 17.5 million doses of Pfizer & Moderna vaccine were administered between Dec 14 – Jan 18, in USA.
Only 66 cases of anaphylaxis were reported & all but 1 case occurred within 11 min of vaccination.
0 deaths.https://t.co/P1YJISkHZE
— Isaac Bogoch (@BogochIsaac) February 12, 2021
CDC says it’s safe to reopen schools — with proper precautions
15 Feb, 2021 | 01:09h | UTCCDC says it’s safe to reopen schools — with proper precautions – Vox
See also: CDC Offers Clearest Guidance Yet For Reopening Schools – NPR
Guideline: Schools and Child Care Programs – Centers for Disease Control and Prevention
[Preprint] Covid-19 vaccination associated with reduced viral load, may reduce transmission
15 Feb, 2021 | 01:07h | UTCDecreased SARS-CoV-2 viral load following vaccination – medRxiv
Commentary: COVID-19 vaccination associated with 3- to 5-fold reduction in viral load – News Medical
Increase aerosol transmission of Covid-19 with increased age and obesity
15 Feb, 2021 | 01:03h | UTCCommentary: Older, heavier adults possible ‘superspreaders’ of COVID-19, study finds – UPI AND Researchers unravel what makes someone a COVID-19 super-spreader – Tulane University
France’s health authority recommends single vaccine shot for people who have had COVID-19
15 Feb, 2021 | 01:02h | UTCFrance’s health authority recommends single vaccine shot for people who have had COVID-19 – Euronews
See also: Covid: France says just one jab needed for previously infected – BBC
Related: Covid-19: People who have had infection might only need one dose of mRNA vaccine – The BMJ AND You’ve had COVID: maybe one dose of vaccine is enough, studies suggest – MedicalXpress
RCT: Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma
15 Feb, 2021 | 00:36h | UTCLenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Lenvatinib plus either pembrolizumab or everolimus was compared with sunitinib as first-line therapy for advanced renal cell cancer. Progression-free survival was significantly longer with lenvatinib plus pembrolizumab than with sunitinib.
— NEJM (@NEJM) February 13, 2021
RCT: Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma
15 Feb, 2021 | 00:34h | UTCEnfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)
RCT: A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma
15 Feb, 2021 | 00:32h | UTCA comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Cabozantinib most effective treatment for metastatic papillary kidney cancer – MedicalXpress
RCT: Radiopharmaceutical therapy vs. cabazitaxel in patients with metastatic castration-resistant prostate cancer
15 Feb, 2021 | 00:29h | UTC[177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Radionuclide Tx Wins in Third-Line Metastatic CRPC – MedPage Today
Long-term data: No difference in cardiovascular mortality or morbidity with transdermal estradiol vs. LHRH agonists for androgen suppression in prostate cancer
15 Feb, 2021 | 00:31h | UTCTransdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme – The Lancet (link to abstract – $ for full-text)