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Daily Archives: January 12, 2021

Blood plasma treatment has limited effect for sickest COVID-19 patients

12 Jan, 2021 | 02:07h | UTC

Blood plasma treatment has limited effect for sickest COVID-19 patients – Imperial College London

See also: Expert reaction to REMAP-CAP recruitment of severely ill COVID-19 patients into convalescent plasma trial being paused after initial analysis suggested it did not improve outcomes – Science Media Centre AND Trial of COVID-19 blood plasma finds no benefit in severely ill patients – Reuters

 

Randomized trial: Plasma therapy administered early is beneficial in high-risk elderly patients

12 Jan, 2021 | 02:05h | UTC

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults – New England Journal of Medicine

Commentaries: Early convalescent plasma may lower risk of severe COVID in seniors – CIDRAP AND Covid-19: Early Plasma Treatment Improved Outcomes in Older Patients – Physician’s Weekly

 

Commentaries on Twitter

 

Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19

12 Jan, 2021 | 01:59h | UTC

Continuation versus discontinuation of renin–angiotensin system inhibitors in patients admitted to hospital with COVID-19: a prospective, randomised, open-label trial – The Lancet Respiratory Medicine

Commentary: Commonly used blood pressure medications safe for COVID-19 patients, study finds – University of Pennsylvania School of Medicine

 

 

CDC Study: Reducing quarantine to fewer than 14 days might be easier to comply with but carries some risk of spreading the virus

12 Jan, 2021 | 02:03h | UTC

Implications of Shortened Quarantine Among Household Contacts of Index Patients with Confirmed SARS-CoV-2 Infection — Tennessee and Wisconsin, April–September 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: Shorter Quarantines Can Eliminate Most Contagion. Is Most Enough? New Data – Brief19 AND Some Transmission of SARS-CoV-2 Occurs After Seven, 10 Days – Physician’s Wekly

Related (guideline and commentary): Why the CDC changed its Covid-19 quarantine guidelines

 

Commentary on Twitter

 

CDC Study: Among young, healthy athletes exposed to Covid-19, the probability of receiving positive test results after day 10 of quarantine is low (less than 5%)

12 Jan, 2021 | 02:01h | UTC

Time from Start of Quarantine to SARS-CoV-2 Positive Test Among Quarantined College and University Athletes — 17 States, June–October 2020 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 

Opinion: Even during a pandemic, hospitals must make family visits and communication the standard of care

12 Jan, 2021 | 01:58h | UTC

Even during a pandemic, hospitals must make family visits and communication the standard of care – STAT

 

Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19

12 Jan, 2021 | 01:55h | UTC

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study – The Lancet Respiratory Medicine

Commentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center

 

AAP: COVID-19 Guidance for Safe Schools

12 Jan, 2021 | 01:56h | UTC

COVID-19 Guidance for Safe Schools – American Academy of Pediatrics

Commentary: AAP updates guidance for in-school education – Contemporary Pediatrics

 

Perspective: Maintaining safety with SARS-CoV-2 vaccines

12 Jan, 2021 | 01:53h | UTC

Maintaining Safety with SARS-CoV-2 Vaccines – New England Journal of Medicine

 

Commentary on Twitter

 

CDC Report: Anaphylaxis after Pfizer-BioNTech COVID-19 vaccine is rare (11.1 cases per million doses)

12 Jan, 2021 | 01:52h | UTC

Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine — United States, December 14–23, 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: CDC says severe allergic reactions to coronavirus vaccine are rare – CNN AND CDC reports more allergic reactions to Covid-19 vaccines, but cases remain few – STAT

 

Randomized trial: Effectiveness of a nurse-led multidisciplinary intervention vs. usual care on advance care planning for vulnerable older adults

12 Jan, 2021 | 01:45h | UTC

Effectiveness of a Nurse-Led Multidisciplinary Intervention vs Usual Care on Advance Care Planning for Vulnerable Older Adults in an Accountable Care Organization: A Randomized Clinical Trial – JAMA Internal Medicine

Editorial: Advance Care Planning and the Cost of Pragmatism (free for a limited period)

Commentary: Nurse Navigation Increases Advance Care Planning – Oncology Nursing News

 

Commentary on Twitter

 

Atrial fibrillation and stroke prevention: state of the art—epidemiology and pathophysiology: New risk factors, concepts and controversies

12 Jan, 2021 | 01:47h | UTC

Atrial fibrillation and stroke prevention: state of the art—epidemiology and pathophysiology: new risk factors, concepts and controversies – European Heart Journal

 

ACC Consensus: Anticoagulation and antiplatelet therapy in patients with atrial fibrillation or venous thromboembolism undergoing PCI or with atherosclerotic cardiovascular disease

12 Jan, 2021 | 01:50h | UTC

2020 ACC Expert Consensus Decision Pathway for Anticoagulant and Antiplatelet Therapy in Patients With Atrial Fibrillation or Venous Thromboembolism Undergoing Percutaneous Coronary Intervention or With Atherosclerotic Cardiovascular Disease: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Commentaries: ACC Issues New Guidance Around Antithrombotic Choices in A-fib, VTE – TCTMD AND ACC Issues Clinical Guidance For Antithrombotic Therapy in Patients With AFib or VTE Undergoing PCI or With ASCVD – American College of Cardiology

 

Commentary on Twitter

 

New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise

12 Jan, 2021 | 01:40h | UTC

New Guidance for Type 1 Diabetes Continuous Glucose Monitoring Use During Exercise – JAMA

Original Guideline: Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA) – Diabetologia

 

Managing conflicts of interest in the development of health guidelines

12 Jan, 2021 | 01:41h | UTC

Managing conflicts of interest in the development of health guidelines – Canadian Medical Association Journal

Related Guidance: Guidelines International Network: Principles for Disclosure of Interests and Management of Conflicts in Guidelines – Annals of Internal Medicine

 

Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms

12 Jan, 2021 | 01:38h | UTC

Association of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm – JAMA Surgery (free for a limited period)

Commentaries: Fluoroquinolones and Aortic Disease—Is It Time to Broaden the Warning? – JAMA (free for a limited period) AND Study links fluoroquinolones to higher risk of aneurysm – CIDRAP AND Analysis Links Fluoroquinolones to Increased Aortic Aneurysm Risk – Physician’s Weekly

 

The Top Nephrology Stories of 2020

12 Jan, 2021 | 01:33h | UTC

The Top Nephrology Stories of 2020 – NephJC

 

Randomized trial: Early interdisciplinary supportive care in patients with previously untreated metastatic esophagogastric cancer

12 Jan, 2021 | 01:36h | UTC

Early Interdisciplinary Supportive Care in Patients With Previously Untreated Metastatic Esophagogastric Cancer: A Phase III Randomized Controlled Trial – Journal of Clinical Oncology

 

Commentaries on Twitter

 

Year in Review: Top Infectious Diseases Articles Of 2020

12 Jan, 2021 | 01:31h | UTC

Year In Review: Top Infectious Diseases Articles Of 2020 – IDStewardship

 

Artificial intelligence in telemetry: What clinicians should know

12 Jan, 2021 | 01:21h | UTC

Artificial intelligence in telemetry: what clinicians should know – Intensive Care Medicine

 

Commentary on Twitter

 

Systematic Review: “For the general population of persons with elevated blood pressure, the benefits of trying to achieve a lower blood pressure target rather than a standard target (140/90 mm Hg or less) do not outweigh the harms associated with that intervention.”

12 Jan, 2021 | 01:30h | UTC

Blood pressure targets in adults with hypertension – Cochrane Library

Summary: The use of lower blood pressure targets for people with hypertension – Cochrane Library

Related systematic review: Blood pressure targets in people with cardiovascular disease – Cochrane Library

 

Commentary on Twitter

 

Special Issue: Fundamentals and innovations in regional anesthesia

12 Jan, 2021 | 01:28h | UTC

Editorial: Advancing towards the next frontier in regional anaesthesia

 

Multiple trauma management in mountain environments – a scoping review

12 Jan, 2021 | 01:25h | UTC

Multiple trauma management in mountain environments – a scoping review – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

 

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

12 Jan, 2021 | 01:26h | UTC

Three-Year Follow-up of 2-Dose Versus 3-Dose HPV Vaccine – Pediatrics (link to abstract – $ for full-text)

 

[Abstract Only] Randomized trial: No difference in long-term outcomes with endovascular revascularization plus supervised exercise vs. supervised exercise only for intermittent claudication

12 Jan, 2021 | 01:15h | UTC

Long-Term Follow-up of a Randomized Clinical Trial Comparing Endovascular Revascularization Plus Supervised Exercise with Supervised Exercise only for Intermittent Claudication – Annals of Surgery (link to abstract – $ for full-text)

 

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