Daily Archives: November 25, 2020
Randomized trial: Convalescent Plasma does not improve clinical status or overall mortality in severe Covid-19 pneumonia
25 Nov, 2020 | 09:17h | UTCCommentary: New trial of convalescent plasma for covid-19 falls flat, another setback for hyped treatment – Brief19
Commentary on Twitter
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia @NEJM A well conducted RCT shows no significant differences in clinical status or overall mortality between patients treated with CP and those who received placebo. https://t.co/C6NylbO2At
— Carlos del Rio (@CarlosdelRio7) November 24, 2020
Cluster-randomized trial: Postexposure hydroxychloroquine does not prevent Covid-19 in healthy persons exposed to a PCR-positive case patient
25 Nov, 2020 | 09:15h | UTC
Commentary on Twitter
Another RCT in @NEJM of outpatient treatment with Hydroxychloroquine in high risk folks to prevent COVID transmission
No benefit
But about 10X rate of adverse events in HCQ group
Happy to keep studying HCQ
But it really doesn't look like it workshttps://t.co/9nAfir0CMX
— Ashish K. Jha, MD, MPH (@ashishkjha) November 24, 2020
[Preprint] Study shows cloth face coverings help protect both wearers and those nearby. Study design represents conditions closer to real-world use, with the control of laboratory testing
25 Nov, 2020 | 09:11h | UTCStudy shows cloth face coverings help protect both wearers and those nearby – Virginia Tech
Original study: Inward and outward effectiveness of cloth masks, a surgical mask, and a face shield – medRxiv
With more data on its COVID-19 vaccine, Russian institute offers new evidence of success
25 Nov, 2020 | 09:13h | UTCWith more data on its COVID-19 vaccine, Russian institute offers new evidence of success – Science
Commentaries: Expert reaction to press release reporting the second interim analysis of the efficacy of the Sputnik V vaccine – Science Media Centre AND Russia says Sputnik V virus vaccine 95% effective – MedicalXpress
Opinion: “Children may transmit coronavirus at the same rate as adults: what we now know about schools and COVID-19”
25 Nov, 2020 | 09:09h | UTC
Commentary from the author on Twitter
I've written a new article describing what we know about children, schools, & #COVID19.
➡️ Children & adults are equally susceptible, & likely transmit the virus at the same rate.
➡️ Schools are a driver of the second wave in Europe, Canada, & elsewhere.https://t.co/25T9HwHBlt
— Dr Zoë Hyde (@DrZoeHyde) November 24, 2020
Latest COVID-19 guidelines come out against bamlanivimab, remdesivir
25 Nov, 2020 | 09:10h | UTCLatest COVID-19 guidelines come out against bamlanivimab, remdesivir – ACP Internist
Systematic review: Financial payments from the pharmaceutical industry is associated with more physician prescribing of the drug made by the company that they got the payments from
25 Nov, 2020 | 09:07h | UTCAre Financial Payments From the Pharmaceutical Industry Associated With Physician Prescribing? A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Financial payments from drug industry associated with physician prescribing – American College of Physicians
Commentary from the author on Twitter (thread – click for more)
"Are Financial Payments From the Pharmaceutical Industry Associated With Physician Prescribing?"
Our latest on physician-industry COI is out today in @AnnalsofIM!Not to bury the lede, the answer is "yes."
Thread to follow.https://t.co/2lfAjWSQuq
1/— Aaron Mitchell (@TheWonkologist) November 24, 2020
Randomized trial: Prednisone is an effective short-term preventive therapy in patients with episodic cluster headache
25 Nov, 2020 | 09:01h | UTCSafety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary from the author on Twitter
Finally published online! After countless years and a lot of work our study on prednisone for the treatment of episodic cluster headache. Thanks to all the many people that were involved in this study, Very proud!!! #PredCH #Clusterheadachehttps://t.co/d88TUWTY5i
— Mark Obermann (@moeb07) November 25, 2020
Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy
25 Nov, 2020 | 09:05h | UTCColorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)
USPSTF Statement recommends regular behavioral counseling on healthy diet and physical activity to prevent cardiovascular disease
25 Nov, 2020 | 08:59h | UTCAuthor interview: Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults With Cardiovascular Risk Factors
JAMA Patient Page: Counseling on Healthy Diet and Physical Activity to Prevent Cardiovascular Disease