Daily Archives: November 17, 2020
Surveillance of wastewater revealed peaks of SARS-CoV-2 preceding those of hospitalized patients with COVID-19
17 Nov, 2020 | 09:53h | UTC
CDC Report: Multiple COVID-19 outbreaks linked to a wedding reception
17 Nov, 2020 | 09:51h | UTCCommentaries: CDC: One wedding led to 177 cases of COVID-19 and 7 deaths because attendees refused to wear masks and physically distance – Business Insider AND Maine wedding outbreak offers a cautionary Covid-19 tale for the holidays – CNN AND Maine Wedding Gives Half Of The Guests Coronavirus, Outbreak Leads To 177 Covid-19 Cases And 7 Deaths – Forbes
[Press release – not published yet] Moderna’s COVID-19 vaccine candidate shows 94.5% protection in an interim analysis of the phase 3 COVE study
17 Nov, 2020 | 09:55h | UTCPress release: Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study
See also: Moderna Announces Longer Shelf Life for its COVID-19 Vaccine Candidate at Refrigerated Temperatures
Commentaries: What Moderna’s Covid-19 vaccine results mean for ending the pandemic – Vox AND Moderna follows Pfizer with exciting vaccine news – how to read these dramatic developments – The Conversation AND Moderna’s COVID Vaccine Is 95% Effective – Independent NIH-Appointed Board Assessment – Higher Storage Temperature Make It Even Better News – Health Policy Watch AND Moderna’s Vaccine News “Encouraging” But Won’t Solve Immediate Problem of Virus Surge in Europe & Americas – WHO – Health Policy Watch AND COVID vaccine excitement builds as Moderna reports third positive result – Nature AND Moderna’s Covid-19 vaccine is strongly effective, early look at data show – STAT AND With strong data on two Covid-19 vaccines, we have more answers about the road ahead — and questions too – STAT AND Early data show Moderna’s COVID vaccine 94.5% effective – CIDRAP AND A Note Of Caution On Moderna’s Promising Covid-19 Vaccine News – Forbes AND Promising Interim Results from Clinical Trial of NIH-Moderna COVID-19 Vaccine – NIH News Releases AND Moderna: Covid vaccine shows nearly 95% protection – BBC AND Latest vaccine success is good news but high price may restrict access – The Guardian AND ‘Just beautiful’—Another COVID-19 vaccine, from newcomer Moderna, succeeds in large-scale trial – Science AND Moderna trial success gives world more hope in race to end pandemic – Reuters AND Expert reaction to Moderna announcement of its phase 3 vaccine interim results – Science Media Centre
CDC Report: Mental health-related emergency department visits among children aged under 18 years raised during the COVID-19 Pandemic
17 Nov, 2020 | 09:48h | UTCCommentary: ER Data Indicates the Pandemic Is Harming Children’s Mental Health – U.S. News
Commentary on Twitter
New @CDCMMWR suggests that the #COVID19 pandemic may be negatively impacting children’s mental health. The proportion of emergency room visits for mental health concerns in children & adolescents increased substantially this past Mar.-Oct. Read the report: https://t.co/9FyLoCzrza pic.twitter.com/fIXMIZg7KK
— CDC (@CDCgov) November 12, 2020
CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care
17 Nov, 2020 | 09:46h | UTCCommentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail
Commentary on Twitter
A new @CDCMMWR finds 9% of the more than 100,000 patients discharged after being hospitalized for #COVID19 were readmitted to the same hospital within 2 months. Learn more: https://t.co/s96NXLxQUE. pic.twitter.com/ugJq9f1gHP
— CDC (@CDCgov) November 9, 2020
The Great Coronavirus Pandemic of 2020—7 Critical Lessons
17 Nov, 2020 | 09:42h | UTCThe Great Coronavirus Pandemic of 2020—7 Critical Lessons – JAMA
Commentary on Twitter
1. Build Resilient Health Systems
2. Leadership and Public Trust Matter
3. Science and Public Health Matters
4. Biomedical Research and Development Matters
5. Equity Matters
6. Evidence-Based Law Matters
7. Global Institutions Matter https://t.co/czxGwyAGCn @LawrenceGostin— JAMA (@JAMA_current) November 16, 2020
Review: Prone positioning for patients with hypoxic respiratory failure related to COVID-19
17 Nov, 2020 | 09:41h | UTC
Commentary on Twitter
What's the evidence for prone positioning for patients with respiratory distress related to #COVID19? A new review answers pressing questions about this common intervention: https://t.co/dh15AuUpD0 #ICU #CriticalCare pic.twitter.com/Y8TzactS70
— CMAJ (@CMAJ) November 11, 2020
Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies
17 Nov, 2020 | 09:40h | UTCEditorial: Management of Community-Acquired Pneumonia in Immunocompromised Adults – CHEST
Systematic review: Evidence-based practices for acute respiratory failure and Acute Respiratory Distress Syndrome
17 Nov, 2020 | 09:37h | UTCCommentary: Best practices for mechanical ventilation in patients with ARDS, COVID-19 – University of Michigan
Primary care guidance for persons with HIV: 2020 update by the HIV Medicine Association of the Infectious Diseases Society of America
17 Nov, 2020 | 09:36h | UTCNews Release: IDSA and HIVMA Release New Comprehensive Primary Care Guidance for People with HIV – Infectious Diseases Society of America
[Abstract Only] In a Phase 2 randomized trial, Semaglutide at high doses improved Nonalcoholic Steatohepatitis (NASH), but with no significant beneficial effects in liver fibrosis
17 Nov, 2020 | 09:31h | UTCA Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Semaglutide Shows Promise in NASH Phase 2 Study – Medscape (free registration required)
Commentary on Twitter
Patients with nonalcoholic steatohepatitis were randomly assigned to receive subcutaneous semaglutide or placebo. The incidence of NASH resolution was significantly higher with semaglutide than with placebo. #LiverMtg20
— NEJM (@NEJM) November 13, 2020
Podcast on Wilderness Medicine: Pearls on altitude sickness, frostbite, animal bites, thermoregulation, and wound care
17 Nov, 2020 | 09:32h | UTC#242 Wilderness Medicine: Prepare for Disaster – The Curbsiders Internal Medicine Podcast
Worldwide measles deaths climb 50% from 2016 to 2019, claiming over 207 500 lives in 2019
17 Nov, 2020 | 09:34h | UTCSee also: Action needed now to prevent further increases in measles and measles deaths in the coming years – The Lancet AND Progress Toward Regional Measles Elimination — Worldwide, 2000–2019 – CDC Morbidity and Mortality Weekly Report
Commentary on Twitter
NEW—Action needed now to prevent further increases in #measles and measles deaths in the coming years
Kim Mulholland, Katrina Kretsinger, Liya Wondwossen & Natasha Crowcroft lay out three pillars of action needed to address this concerning situation https://t.co/m6nD6yupMp pic.twitter.com/njd5PD9K3s
— The Lancet (@TheLancet) November 13, 2020
Sleep problems in dementia: Despite many drugs being widely prescribed, systematic review finds lack of evidence and no randomized controlled trials to guide decisions about drug treatment
17 Nov, 2020 | 09:29h | UTCPharmacotherapies for sleep disturbances in dementia – Cochrane Library