Daily Archives: February 9, 2020 | LinksMedicus Free Medical News & Perspectives

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

9 Feb, 2020 | 20:50h | UTC

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children – Pediatric Critical Care Medicine (free)

Executive Summary: Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (free)

Related Commentary on Twitter

The #SurvivingSepsis Campaign has released NEW peds sepsis guidelines that recommend child-specific care for this deadly condition. Access the full guidelines published in @PedCritCareMed: https://t.co/Yjfa5kaXtb

More resources: https://t.co/R4bivYQWuA #SCCMSoMe #PedsICU pic.twitter.com/o9FslT2c6I

— SCCM (@SCCM) February 8, 2020

Mon February 10 – 10 Stories of The Day!

9 Feb, 2020 | 21:10h | UTC

1 – Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children – Pediatric Critical Care Medicine (free)

Executive Summary: Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (free)

2 – De-implementing wisely: developing the evidence base to reduce low-value care – BMJ Quality & Safety (free) (via @brhospitalist)

3 – Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation – European Heart Journal (free)

Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)

4 – Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)

5 – Potential Consequences of Changing Disease Classifications – JAMA (free for a limited period)

Author Interview: Potential Consequences of Changing Disease Classifications (free audio)

6 – Abolish the Tilt Table Test for the Workup of Syncope! – Circulation (free for a limited period)

7 – Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

8 – Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology – Journal of Clinical Oncology (free)

9 – Novel Coronavirus – Selected News & Perspectives / 10 February 2020

China nCoV cases continue at stable rate, concerns rise about spread in Singapore – CIDRAP (free)
Coronavirus—Unknown Source, Unrecognized Spread, and Pandemic Potential – Think Global Health (free)
WHO cautions that transmission of the new coronavirus outside of China could increase – STAT (free)
New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free)
Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) A
Demand for masks soars 100-fold, disrupting coronavirus fight: WHO – Reuters (free)
China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free)
Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
Did pangolins spread the China coronavirus to people? – Nature (free)
Scientists question work suggesting pangolin coronavirus link – Reuters (free)
The US coronavirus travel ban could backfire. Here’s how – CNN (free)
Coronavirus: WHO chief warns against ‘trolls and conspiracy theories’ – BBC (free)

10 – Novel Coronavirus – Latest Articles / 10 February 2020

Guidelines:

Top Articles / Articles in High Impact Journals:

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China – JAMA (free) AND Commentaries: New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free) AND Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) AND New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
Preprint: Clinical characteristics of 2019 novel coronavirus infection in China – medRxiv (free PDF) (via @greg_folkers see Tweet) (Preprint with description of 1099 patients).
Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China – JAMA (free)
Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province, China – Intensive Care Medicine (free)
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro – Cell Research (free) AND Commentaries: China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free) AND Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (Manis javanica) – Viruses (free) AND Commentaries: Did pangolins spread the China coronavirus to people? – Nature (free) AND Scientists question work suggesting pangolin coronavirus link – Reuters (free)
Scientists are racing to model the next moves of a coronavirus that’s still hard to predict – Science (free)
China coronavirus: labs worldwide scramble to analyse live samples – Nature (free)
Emerging Coronavirus 2019-nCoV Pneumonia – Radiology (free)

Podcast:

The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD – JAMA (free audio)

Other Articles:

Preprints:

Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism

9 Feb, 2020 | 20:45h | UTC

Diagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)

Related Commentary on Twitter

JAMA Insights: the presentation and diagnostic workup of primary #hyperparathyroidism, and indications for surgical vs surveillance management. https://t.co/kUg9WeCCsc

— JAMA (@JAMA_current) February 8, 2020

Study: Lower GI-bleeding in Anticoagulated Patients with Atrial Fibrillation Should Always Raise Suspicion of Colorectal Cancer

9 Feb, 2020 | 20:47h | UTC

Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation – European Heart Journal (free)

Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)

De-implementing Wisely: Developing the Evidence Base to Reduce Low-value Care

9 Feb, 2020 | 20:49h | UTC

De-implementing wisely: developing the evidence base to reduce low-value care – BMJ Quality & Safety (free) (via @brhospitalist)

Opinion: “Abolish the Tilt Table Test for the Workup of Syncope!”

9 Feb, 2020 | 20:41h | UTC

Abolish the Tilt Table Test for the Workup of Syncope! – Circulation (free for a limited period)

[Abstract Only] Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trial

9 Feb, 2020 | 20:39h | UTC

Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

Viewpoint: Potential Consequences of Changing Disease Classifications

9 Feb, 2020 | 20:42h | UTC

Potential Consequences of Changing Disease Classifications – JAMA (free for a limited period)

Author Interview: Potential Consequences of Changing Disease Classifications (free audio)

Novel Coronavirus – Selected News & Perspectives / 10 February 2020

9 Feb, 2020 | 20:34h | UTC

Clinical Cancer Advances 2020: ASCO Annual Report on Progress Against Cancer

9 Feb, 2020 | 20:38h | UTC

Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology – Journal of Clinical Oncology (free)

Primary Lateral Sclerosis: Consensus Diagnostic Criteria

9 Feb, 2020 | 20:24h | UTC

Primary lateral sclerosis: consensus diagnostic criteria – Journal of Neurology, Neurosurgery & Psychiatry (free)

ASA Practice Advisory for the Perioperative Management of Patients with Cardiac Implantable Electronic Devices: Pacemakers and Implantable Cardioverter–Defibrillators

9 Feb, 2020 | 20:23h | UTC

Practice Advisory for the Perioperative Management of Patients with Cardiac Implantable Electronic Devices: Pacemakers and Implantable Cardioverter–Defibrillators 2020: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Management of Patients with Cardiac Implantable Electronic Devices – Anesthesiology (free)

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy

9 Feb, 2020 | 20:21h | UTC

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt international (free)

An Overview of Precision Oncology Basket and Umbrella Trials for Clinicians

9 Feb, 2020 | 20:19h | UTC

An overview of precision oncology basket and umbrella trials for clinicians – CA: A Cancer Journal for Clinicians (free)

Editorial: Nature Will Publish Peer Review Reports as a Trial

9 Feb, 2020 | 20:17h | UTC

Editorial: Nature will publish peer review reports as a trial – Nature (free)

Review: Drugs for Some Common Eye Disorders

9 Feb, 2020 | 20:15h | UTC

Drugs for Some Common Eye Disorders – JAMA (free for a limited period)

If the link above does not work, try this one

Related Commentary on Twitter

Many artificial tear preparations are available OTC. There is no data that they are any worse at relieving symptoms than the much more expensive prescription cyclosporine emulsion (Restatis) or lifitegrast solution (Xiidra) https://t.co/qEL4IyDfrn

— JAMA (@JAMA_current) February 7, 2020

Review: How I Treat Cancer-associated Thrombosis

9 Feb, 2020 | 20:18h | UTC

How I treat cancer-associated thrombosis – ESMO Open (free)

[Abstract Only] Meta-Analysis: Corticosteroids as Adjunctive Therapy in the Treatment of Influenza

9 Feb, 2020 | 20:13h | UTC

Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis – Critical Care Medicine (link to abstract – $ for full-text)

[Abstract Only] Cohort Study: Blood Pressure Thresholds and Neurologic Outcomes After Endovascular Therapy for Acute Ischemic Stroke

9 Feb, 2020 | 20:16h | UTC

Blood Pressure Thresholds and Neurologic Outcomes After Endovascular Therapy for Acute Ischemic Stroke: An Analysis of Individual Patient Data From 3 Randomized Clinical Trials – JAMA Neurology (link to abstract – $ for full-text)

Commentary: ‘Sweet Spot’ Identified for BP During Stroke Thrombectomy – TCTMD (free) AND Blood Pressure Key to Good Outcomes in Stroke Thrombectomy – Medscape (free registration required)

Related Commentary on Twitter

BP MAP < 70 mmHg for >10 min and > MAP 90 mmHg for > 45 min were associated with worse outcomes in this cohort study of endovascular #stroke patients (n=365). NNH 10.
Blood Pressure Thresholds in Endovascular Therapy for Acute Ischemic Stroke https://t.co/fBFPZcN5CG

— Vivien Lee MD FAAN (@VivienHLee) January 29, 2020

[Abstract Only] Meta-Analysis: Epinephrine Improves Overall Survival but not Neurologic Outcomes for Out-of-Hospital Cardiac Arrest

9 Feb, 2020 | 20:12h | UTC

Epinephrine for Out-of-Hospital Cardiac Arrest: An Updated Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)

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