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Daily Archives: October 2, 2019

Systematic Review: Exercise Training Improves Physical Capacity After Lung Cancer Surgery

2 Oct, 2019 | 22:22h | UTC

Exercise training improves physical capacity after lung cancer surgery – NIHR Signal (free)

Original Cochrane Review: Exercise training undertaken by people within 12 months of lung resection for non‐small cell lung cancer (free)

 


How to Improve Healthcare Improvement—an essay by Mary Dixon-Woods

2 Oct, 2019 | 22:24h | UTC

How to improve healthcare improvement—an essay by Mary Dixon-Woods – The BMJ (free)

 


Consensus Statement: Unmet Therapeutic, Educational and Scientific Needs in Parathyroid Disorders

2 Oct, 2019 | 22:25h | UTC

Unmet therapeutic, educational and scientific needs in parathyroid disorders: Consensus Statement from the first European Society of Endocrinology Workshop (PARAT) – European Journal of Endocrinology (free)

 


[Abstract Only] Randomized Trial: Low-FODMAP Diet is Safe and Effective for Managing Persistent Gut Symptoms in Patients with Inflammatory Bowel Disease

2 Oct, 2019 | 22:23h | UTC

Effects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial – Gastroenterology (link to abstract – $ for full-text)

Commentary: FODMAPs diet relieves symptoms of inflammatory bowel disease – King’s College London (free)

 


ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia

2 Oct, 2019 | 02:14h | UTC

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine (free)

News Release: ATS/IDSA publishes clinical guideline on community acquired pneumonia – American Thoracic Society (free)

See also: Executive Summary (free PDF)

 


Study: Male Infertility Linked to Increased Risk of Prostate Cancer

2 Oct, 2019 | 22:20h | UTC

Risk of prostate cancer for men fathering through assisted reproduction: nationwide population based register study – The BMJ (free)

Editorial: Male infertility linked to risk of prostate cancer (free)

Commentaries: Assisted reproduction and risk of prostate cancer for men – The BMJ Opinion (free) AND Fathering children by assisted reproduction linked to increased risk of prostate cancer – The BMJ (free) AND Male infertility linked to prostate cancer risk – BBC (free) AND Male infertility linked to increased prostate cancer risk – NHS Choices (free)

 


[Abstract Only] Randomized Trial: Monoclonal Antibody for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps

2 Oct, 2019 | 22:17h | UTC

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials – The Lancet (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Review: Health Problems in Healthcare Workers

2 Oct, 2019 | 22:19h | UTC

Health problems in healthcare workers: A review – Journal of Family Medicine and Primary Care (free)

Related: Whole-system approaches to improving the health and wellbeing of healthcare workers: A systematic review – PLOS One (free) AND Healthcare Staff Wellbeing, Burnout, and Patient Safety: A Systematic Review – PLOS One (free)

 


Guidelines for the Surgical Management of Chronic Lateral Ankle Instability

2 Oct, 2019 | 22:21h | UTC

Clinical Guidelines for the Surgical Management of Chronic Lateral Ankle Instability: A Consensus Reached by Systematic Review of the Available Data – Orthopaedic Journal of Sports Medicine (free)

 


Consensus Statement: Concussion Management in Combat Sports

2 Oct, 2019 | 22:18h | UTC

Concussion management in combat sports: consensus statement from the Association of Ringside Physicians – British Journal of Sports Medicine (free)

 


[Abstract Only] Meta-Analysis: Povidone-iodine 1% is the Most Effective Vaginal Antiseptic for Preventing Post-cesarean Endometritis

2 Oct, 2019 | 22:16h | UTC

Povidone-iodine 1% is the most effective vaginal antiseptic for preventing post-cesarean endometritis: a systematic review and network meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


AL Amyloidosis for the Cardiologist and Oncologist: Epidemiology, Diagnosis, and Management

2 Oct, 2019 | 22:15h | UTC

AL Amyloidosis for the Cardiologist and Oncologist: Epidemiology, Diagnosis, and Management – JACC: CardioOncology (free)

Related: Cardiac Amyloidosis: Updates in Imaging (several reviews on the subject)

 


Meta-Analysis: Healthy Dietary Patterns and Incidence of Chronic Kidney Disease

2 Oct, 2019 | 02:12h | UTC

Healthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies – Clinical Journal of the American Society of Nephrology (free)

Commentaries: A healthy diet may help prevent kidney disease – American Society of Nephrology (free) AND Healthy Diet May Prevent CKD, Albuminuria – Renal & Urology News (free) AND Patient Voice: Diet Patterns and Kidney Disease – Clinical Journal of the American Society of Nephrology (free)

 


Wed October 2 – 10 Stories of The Day!

2 Oct, 2019 | 10:19h | UTC

 

1 – Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine (free)

News Release: ATS/IDSA publishes clinical guideline on community acquired pneumonia – American Thoracic Society (free)

See also: Executive Summary (free PDF)

 

2 – Healthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies – Clinical Journal of the American Society of Nephrology (free)

Commentaries: A healthy diet may help prevent kidney disease – American Society of Nephrology (free) AND Healthy Diet May Prevent CKD, Albuminuria – Renal & Urology News (free) AND Patient Voice: Diet Patterns and Kidney Disease – Clinical Journal of the American Society of Nephrology (free)

 

3 – Special Issue: Obstetric Anaesthesia – Update in Anaesthesia (free articles)

– Homepage

– Obstetric anaesthesia in resource limited settings 

– Obstetric airway management 

– General anesthesia for elective cesarean section in resource-limited settings 

– Obstetric spinal anaesthesia 

– Management of total spinal block in obstetrics 

– Labour epidural the basics 

– Labour epidural troubleshooting 

– Establishing an epidural service for labour analgesia in a variable resource environment 

– Emergency management of maternal collapse and arrest 

– Pre-eclampsia – prevention, diagnosis and management 

– Placental pathology: a review of placenta previa, placental abruption and placenta accreta 

– Anaesthetic implications of morbid obesity in pregnancy 

– Update in obstetric trauma management 

– Update in obstetric maternal sepsis 

– Oxytocics 

– Obstetric and foetal physiology

– Newborn resuscitation

– Anaesthesia for non obstetric surgery during pregnancy

Source: Critical Care Reviews Newsletter

 

4 – Chronic Kidney Disease Diagnosis and Management: A Review – JAMA (free for a limited period)

 

5 – Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Is High-Dose Vitamin C Beneficial for Patients With Sepsis? (free)

Commentary: ‘Tantalizing’ Results For A Test Of Vitamin C For Sepsis – NPR (free)

In exploratory analyses that did not adjust for multiple comparisons, 3 secondary outcomes (out of 46 examined) were significantly different between groups. At day 28, mortality was 46.3% (38/82) in the placebo group vs 29.8% (25/84) in the vitamin C group (P = .03). The number of ICU-free days to day 28 was 10.7 in the vitamin C group vs 7.7 in the placebo group (P = .03). The number of hospital-free days in the vitamin C group vs the placebo group was 22.6 vs 15.5, respectively (P = .04)

 

6 – Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free)

See also: Is eating beef healthy? The new fight raging in nutrition science, explained. – Vox (free)

Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and commentaries)

 

7 – Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)

 

8 – Smoking reduction interventions for smoking cessation – Cochrane Library (free)

Summary: Can people stop smoking by cutting down the amount they smoke first? – Cochrane Library (free)

 

9 – Long-term outcomes of childhood sexual abuse: an umbrella review – The Lancet Psychiatry (free)

Commentaries: Understanding and responding to the long-term burdens of childhood sexual abuse – The Lancet Psychiatry (free) AND Childhood sexual abuse linked to a range of physical and mental health conditions – University of Oxford (free)

 

10 – Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials – The Lancet (link to abstract – $ for full-text)

Commentaries: Asthma 3-in-1 Therapy May Improve Lung Function, Study Shows – The New York Times (10 articles per month are free) AND Triple-Therapy Inhaler Tied to Better Lung Function in Asthma – NEJM Journal Watch (free)

 


Systematic Review: Can People Stop Smoking by Cutting Down the Amount they Smoke First?

2 Oct, 2019 | 01:51h | UTC

Smoking reduction interventions for smoking cessation – Cochrane Library (free)

Summary: Can people stop smoking by cutting down the amount they smoke first? – Cochrane Library (free)

 


Review: Chronic Kidney Disease Diagnosis and Management

2 Oct, 2019 | 02:06h | UTC

Chronic Kidney Disease Diagnosis and Management: A Review – JAMA (free for a limited period)

 


Special Issue: Obstetric Anesthesia

2 Oct, 2019 | 02:08h | UTC

Obstetric Anaesthesia – Update in Anaesthesia (free articles)

– Homepage

– Obstetric anaesthesia in resource limited settings

– Obstetric airway management 

– General anesthesia for elective cesarean section in resource-limited settings 

– Obstetric spinal anaesthesia 

– Management of total spinal block in obstetrics 

– Labour epidural the basics 

– Labour epidural troubleshooting 

– Establishing an epidural service for labour analgesia in a variable resource environment 

– Emergency management of maternal collapse and arrest

– Pre-eclampsia – prevention, diagnosis and management 

– Placental pathology: a review of placenta previa, placental abruption and placenta accreta 

– Anaesthetic implications of morbid obesity in pregnancy 

– Update in obstetric trauma management 

– Update in obstetric maternal sepsis 

– Oxytocics 

– Obstetric and foetal physiology

– Newborn resuscitation

– Anaesthesia for non obstetric surgery during pregnancy

Source: Critical Care Reviews Newsletter

 


Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data

2 Oct, 2019 | 02:02h | UTC

Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free)

See also: Is eating beef healthy? The new fight raging in nutrition science, explained. – Vox (free)

Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and commentaries)

 


[Abstract Only] Cohort Study: Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns

2 Oct, 2019 | 01:53h | UTC

Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)

 


Guidelines for Diagnostic Flexible Bronchoscopy in Adults

2 Oct, 2019 | 01:33h | UTC

Guidelines for Diagnostic Flexible Bronchoscopy in Adults: Joint Indian Chest Society/National College of Chest Physicians (I)/Indian Association for Bronchology Recommendations – Lung India (free)

Related Guidelines: British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE – Thorax (free) AND ERS statement: interventional bronchoscopy in children – European Respiratory Journal (free)

 


Randomized Trial: Conflicting Results in Small Trial Testing Vitamin C for Sepsis and Severe Acute Respiratory Failure, Further Trials are Required

2 Oct, 2019 | 02:04h | UTC

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Is High-Dose Vitamin C Beneficial for Patients With Sepsis? (free)

Commentary: ‘Tantalizing’ Results For A Test Of Vitamin C For Sepsis – NPR (free)

In exploratory analyses that did not adjust for multiple comparisons, 3 secondary outcomes (out of 46 examined) were significantly different between groups. At day 28, mortality was 46.3% (38/82) in the placebo group vs 29.8% (25/84) in the vitamin C group (P = .03). The number of ICU-free days to day 28 was 10.7 in the vitamin C group vs 7.7 in the placebo group (P = .03). The number of hospital-free days in the vitamin C group vs the placebo group was 22.6 vs 15.5, respectively (P = .04).

 


[Abstract Only] Randomized Trial: Triple Therapy Inhaler for Uncontrolled Asthma

2 Oct, 2019 | 01:45h | UTC

Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials – The Lancet (link to abstract – $ for full-text)

Commentaries: Asthma 3-in-1 Therapy May Improve Lung Function, Study Shows – The New York Times (10 articles per month are free) AND Triple-Therapy Inhaler Tied to Better Lung Function in Asthma – NEJM Journal Watch (free)

 


Umbrella Review: Long-term Outcomes of Childhood Sexual Abuse

2 Oct, 2019 | 01:48h | UTC

Long-term outcomes of childhood sexual abuse: an umbrella review – The Lancet Psychiatry (free)

Commentaries: Understanding and responding to the long-term burdens of childhood sexual abuse – The Lancet Psychiatry (free) AND Childhood sexual abuse linked to a range of physical and mental health conditions – University of Oxford (free)

 


Study Review: C-reactive Protein Testing in General Practice Safely Reduces Antibiotic use for COPD Flare-ups

2 Oct, 2019 | 01:43h | UTC

C-reactive protein testing in general practice safely reduces antibiotic use for COPD flare-ups – NIHR Signal (free)

Original Study: Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations (link to abstract and commentaries)

 


FDA Warns About Rare Occurrence of Serious Liver Injury with Use of Hepatitis C Medicines in Some Patients with Advanced Liver Disease

2 Oct, 2019 | 01:41h | UTC

FDA warns about rare occurrence of serious liver injury with use of hepatitis C medicines Mavyret, Zepatier, and Vosevi in some patients with advanced liver disease – U.S. Food & Drug Administration (free)

Commentary: Hepatitis C medicines have led to liver decompensation in some patients – ACP Gastroenterology (free)

 


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