Daily Archives: August 11, 2019
Guideline: Management of Acute Liver Failure
11 Aug, 2019 | 22:27h | UTCManagement of acute liver failure. Clinical guideline from the Catalan Society of Digestology – Gastroenterología y Hepatología (free for a limited period)
Related Guideline: American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure – Gastroenterology (free)
Source: Critical Care Reviews Newsletter
Guidelines for Esophageal Manometry and Esophageal Reflux Monitoring
11 Aug, 2019 | 22:26h | UTC
Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes
11 Aug, 2019 | 22:24h | UTC“α-Glucosidase inhibitors, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, metformin, orlistat, phentermine/topiramate, and pioglitazone significantly reduced the risk of biochemical conversion to T2DM, whereas statins and nateglinide increased the risk”
Too Much Medicine: Not Enough trust?
11 Aug, 2019 | 22:18h | UTCToo Much Medicine: Not Enough trust? – Journal of Medical Ethics (free)
Related Commentary on Twitter
A really thoughtful + interesting piece by @DrZoeFritz and #RichardHolton
Are doctors ordering unnecessary tests + over-prescribing because they want patients to trust them?
What are better more ethical ways to gain patient trust? (open access) https://t.co/KPJqC8tTIz— Celia Kitzinger (@KitzingerCelia) August 9, 2019
Meta-Analysis: Alcohol Use in Pregnancy and Miscarriage
11 Aug, 2019 | 22:23h | UTCCommentary: Alcohol exposure during pregnancy linked with dose-dependent increase in miscarriage risk – News Medical (free)
Management of Malnutrition in Older Patients—Current Approaches, Evidence and Open Questions
11 Aug, 2019 | 22:20h | UTCRelated: ESPEN guideline on clinical nutrition and hydration in geriatrics (free)
Viewpoint: Making Machine Learning Models Clinically Useful
11 Aug, 2019 | 22:21h | UTCMaking Machine Learning Models Clinically Useful – JAMA (free for a limited period)
Related JAMA Viewpoints: Artificial Intelligence in Health Care: Will the Value Match the Hype? (free for a limited period) AND Questions for Artificial Intelligence in Health Care (free for a limited period) AND Deep Learning in Medicine—Promise, Progress, and Challenges (free for a limited period)
Study: Many of the “Oldest” People in the World May Not be as Old as we Think
11 Aug, 2019 | 22:16h | UTCStudy: many of the “oldest” people in the world may not be as old as we think – Vox (free)
Meta-Analysis: Neonatal, Infant, and Childhood Growth Following Metformin vs. Insulin Treatment for Gestational Diabetes
11 Aug, 2019 | 22:15h | UTCCommentary: Does metformin treatment for GDM adversely affect offspring? – Univadis (free registration required)
[Abstract Only] Randomized Trial: Mechanical and Oral Antibiotic Bowel Preparation Do Not Reduce Surgical Site Infections or the Overall Morbidity in Elective Colectomy
11 Aug, 2019 | 22:13h | UTCMechanical and oral antibiotic bowel preparation versus no bowel preparation for elective colectomy (MOBILE): a multicentre, randomised, parallel, single-blinded trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Bowel preparation not needed before colon surgery, study says – UPI (free) AND A Finnish study finds bowel preparation for colon surgery unnecessary – University of Helsinki (free)
WHO Statement on Governance and Oversight of Human Genome Editing
11 Aug, 2019 | 21:38h | UTCStatement on governance and oversight of human genome editing – World Health Organization (free)
Commentary: WHO Releases Statement Condemning Further Germline Genome Editing – Frontline Genomics (free)
Related: WHO Expert Panel Paves Way for Strong International Governance on Human Genome Editing (free)
Cohort Study and Meta-Analysis: Long-term Antithrombotic Therapy and Risk of Intracranial Hemorrhage from Cerebral Cavernous Malformations
11 Aug, 2019 | 21:39h | UTCInvited Commentary: Antithrombotics and bleeding risk: paradoxical findings (free)
Related Commentary on Twitter
https://twitter.com/BleedingStroke/status/1159372784377782272
Review: Diagnosis of Patients with Angina and Non-obstructive Coronary Disease in the Catheter Laboratory
11 Aug, 2019 | 21:35h | UTCRelated: Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries (free study, guideline and reviews on the subject)
Traveling With Cancer: A Guide for Oncologists in the Modern World
11 Aug, 2019 | 21:36h | UTCTraveling With Cancer: A Guide for Oncologists in the Modern World – Journal of Global Oncology (free)
[Abstract Only] Study: SGLT2 Inhibitors not Associated with Increased Risk of Severe Urinary Tract Infections
11 Aug, 2019 | 21:37h | UTCSodium–Glucose Cotransporter-2 Inhibitors and the Risk for Severe Urinary Tract Infections: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: SGLT-2 inhibitors not associated with increased risk for severe UTIs – ACP Diabetes (free) AND SGLT2 Inhibitor Use Not Linked to Increased Risk for UTI Events – Endocrinology Advisor (free) AND SGLT-2 inhibitors not associated with increased risk for severe UTI – 2 Minute Medicine (free)
Meta-Analysis: Atrial Fibrillation Ablation with Pulmonary Vein Isolation vs. Without
11 Aug, 2019 | 21:33h | UTC
[Abstract Only] Study: Off-Pump Versus On-Pump Bypass Surgery for Left Main Coronary Artery Disease
11 Aug, 2019 | 21:34h | UTCOff-Pump Versus On-Pump Bypass Surgery for Left Main Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Off- vs. On-Pump Surgery for Left Main Disease – American College of Cardiology (free) Higher Mortality With Off-Pump CABG: EXCEL Analysis – TCTMD (free)
Related Study: Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass (link to abstract and commentaries)
Related Commentary on Twitter
Among patients with left main disease treated with #cvCABG, off-pump surgery is associated with an increased risk of 3-year all-cause death compared to on-pump surgery. https://t.co/mPoMqJcRq2 #JACC pic.twitter.com/eBIXhUvlX2
— JACC Journals (@JACCJournals) August 8, 2019
The Effect of Food Price Changes on Consumer Purchases: A Randomized Experiment
11 Aug, 2019 | 21:32h | UTCCommentaries: Taxes on saturated fat, salt, and sugar improve the healthiness of grocery purchases, but changes are frustratingly small – The Lancet Public Health (free) AND Virtual supermarket shows how food taxes could work – The University of Auckland (free)
Related: Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption (several policies, guidelines, studies and commentaries on the subject) AND AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free statement and commentaries)
Study: “Liquid Biopsy” for Detection of Residual Disease after Neoadjuvant Therapy in Breast Cancer
11 Aug, 2019 | 21:30h | UTCPersonalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer – Science Translational Medicine (free for a limited period)
Commentaries: New ‘liquid biopsy’ blood test improves breast cancer diagnostics – The Translational Genomics Research Institute (free) AND Circulating Tumor DNA Analysis for Detection of Residual Disease in Breast Cancer – The ASCO Post (free) AND Expert reaction to blood test to help tailor treatment for breast cancer patients – Science Media Centre (free)
Study: “Liquid Biopsy” for Relapse Detection in Early-Stage Breast Cancer
11 Aug, 2019 | 21:31h | UTCAssessment of Molecular Relapse Detection in Early-Stage Breast Cancer – JAMA Oncology (free for a limited period)
Commentaries: Circulating Tumor DNA as a Marker for Disease Relapse in Early-Stage Breast Cancer—Bad Blood – JAMA Oncology (free for a limited period) AND Liquid Biopsy in Breast Ca Finds Relapse Early – MedPage Today (free registration required)
Women’s Health 2019: Osteoporosis, Breast Cancer, Contraception, and Hormone Therapy
11 Aug, 2019 | 21:20h | UTC
Myocardial Injury in the Era of High-Sensitivity Cardiac Troponin Assays: A Practical Approach for Clinicians
11 Aug, 2019 | 21:18h | UTCMyocardial Injury in the Era of High-Sensitivity Cardiac Troponin Assays: A Practical Approach for Clinicians – JAMA Cardiology (free for a limited period)
Related: Turkish Society of Cardiology Consensus Paper on The Rational Use of Cardiac Troponins in Daily Practice – The Anatolian Journal of Cardiology (free PDF) AND Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)
Risk, Prevention, Diagnosis, and Management of Post-Operative Cutaneous Infection
11 Aug, 2019 | 21:15h | UTCRelated: Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free) AND Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery(free) AND Global guidelines on the prevention of surgical site infection – World Health Organization
[Abstract Only] Randomized Trial: Adjuvant Hyperthermic Intraperitoneal Chemotherapy Not Effective for Patients with Locally Advanced Colon Cancer
11 Aug, 2019 | 21:17h | UTCAdjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Related Commentary on Twitter
New online – Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial – https://t.co/M3GQw6pfKm #colorectalcancer #crcstm #HIPEC #colorectalresearch pic.twitter.com/FytTdFAyxB
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) July 30, 2019
Systematic Review: Screening for Melanoma is Not Supported or Refuted by Current Evidence
11 Aug, 2019 | 21:16h | UTCScreening for reducing morbidity and mortality in malignant melanoma – Cochrane Library (free)
Summary: Screening for malignant melanoma (a type of skin cancer) – Cochrane Library (free)
Featured Review: Evidence for the benefits and harms of screening for malignant melanoma – Cochrane Library (free)