Daily Archives: July 26, 2019
Fri July 26 – 10 Stories of The Day!
26 Jul, 2019 | 09:46h | UTC
1 – ACG Clinical Guideline: Hereditary Hemochromatosis – The American Journal of Gastroenterology (free PDF)
Related Guidelines: Diagnosis and management of hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases (free) AND Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype – Hepatology International (free)
2 – Clinical Guide and Update on Porphyrias – Gastroenterology (free)
Related Reviews: Update review of the acute porphyrias – British Journal of Haematology (free) AND Acute Hepatic Porphyrias: Review and Recent Progress – Hepatology Communications (free) AND Acute hepatic porphyrias: Recommendations for evaluation and long‐term management – Hepatology (free) AND An overview of the cutaneous porphyrias – F1000 Research (free)
Commentary: Review examines methods for diagnosis of elevated ICP in critically ill – MedicalXpress (free)
Related Guidelines: Management of severe traumatic brain injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free) AND Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)
Related Reviews: Emergency Neurological Life Support: Intracranial Hypertension and Herniation – Neurocritical Care (free) AND Acute Management of Traumatic Brain Injury – Surgical Clinics of North America (free)
Commentary: Long-Term Risk for Recurrent VTE Significant After Stopping Anticoagulation – NEJM Journal Watch (free)
“the risk of recurrent VTE was 10% in the first year after treatment, 16% at two years, 25% at five years, and 36% at 10 years, with 4% of recurrent VTE events resulting in death.”
5 – Harms from Uninformative Clinical Trials – JAMA (free for a limited period)
“An uninformative trial is one that provides results that are not of meaningful use for a patient, clinician, researcher, or policy maker.”
6 – Realizing Shared Decision-making in Practice – JAMA (free for a limited period)
Related Viewpoint: Shared Decision Making and the Importance of Time – JAMA (free)
9 – Interventions for preventing obesity in children – Cochrane Library (free)
Summary: Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? – Cochrane Library (free)
10 – Rhythm control for patients with atrial fibrillation complicated with heart failure in the contemporary era of catheter ablation: a stratified pooled analysis of randomized data – European Heart Journal (link to abstract – $ for full-text)
Commentary: Rhythm Control for Atrial Fibrillation With Heart Failure – American College of Cardiology (free)
Related Meta-Analysis: Catheter Ablation for Atrial Fibrillation Improves Outcomes in Heart Failure with Reduced Ejection Fraction (free)
Meta-analysis: Diagnosis of Elevated Intracranial Pressure in Critically Ill Adults
26 Jul, 2019 | 01:08h | UTCCommentary: Review examines methods for diagnosis of elevated ICP in critically ill – MedicalXpress (free)
Related Guidelines: Management of severe traumatic brain injury (first 24 hours) – Anaesthesia Critical Care & Pain Medicine (free) AND Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)
Related Reviews: Emergency Neurological Life Support: Intracranial Hypertension and Herniation – Neurocritical Care (free) AND Acute Management of Traumatic Brain Injury – Surgical Clinics of North America (free)
Related Commentary on Twitter
A question we often ask in the ED/ICU: Does this patient have increased ICP?
Our @bmj_latest study found that traditional physical exam and CT signs had poor accuracy for elevated ICP. If suspected, consider treatment & transfer for invasive monitoring.https://t.co/1Eb8PtYLFJ pic.twitter.com/bQFIgWnuur
— Shannon Fernando (@shanfernands) July 25, 2019
ACG Clinical Guideline: Hereditary Hemochromatosis
26 Jul, 2019 | 01:13h | UTCACG Clinical Guideline: Hereditary Hemochromatosis – The American Journal of Gastroenterology (free PDF)
Related Guidelines: Diagnosis and management of hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases (free) AND Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype – Hepatology International (free)
Clinical Guide and Update on Porphyrias
26 Jul, 2019 | 01:11h | UTCClinical Guide and Update on Porphyrias – Gastroenterology (free)
Related Reviews: Update review of the acute porphyrias – British Journal of Haematology (free) AND Acute Hepatic Porphyrias: Review and Recent Progress – Hepatology Communications (free) AND Acute hepatic porphyrias: Recommendations for evaluation and long‐term management – Hepatology (free) AND An overview of the cutaneous porphyrias – F1000 Research (free)
Viewpoint: Realizing Shared Decision-making in Practice
26 Jul, 2019 | 01:01h | UTCRealizing Shared Decision-making in Practice – JAMA (free for a limited period)
Related Viewpoint: Shared Decision Making and the Importance of Time – JAMA (free)
Meta-Analysis: Risk of Recurrent Thromboembolism after Discontinuation of Anticoagulant Treatment for First Unprovoked Venous Thromboembolism Event
26 Jul, 2019 | 01:06h | UTCCommentary: Long-Term Risk for Recurrent VTE Significant After Stopping Anticoagulation – NEJM Journal Watch (free)
“the risk of recurrent VTE was 10% in the first year after treatment, 16% at two years, 25% at five years, and 36% at 10 years, with 4% of recurrent VTE events resulting in death.”
Related Commentary on Twitter
Excited to share my first study published today in @bmj_latest on recurrence risk after stopping #anticoagulation for unprovoked #VTE. Big thanks to the MARVELOUS collaborators, @CIHR_IRSC for funding/support & @RodgerMarc for continued mentorship https://t.co/jnT86dRzHK#phdlife pic.twitter.com/SSVTYwkXth
— Faizan Khan (@FaizanK91) July 25, 2019
Viewpoint: Harms from Uninformative Clinical Trials
26 Jul, 2019 | 01:04h | UTCHarms from Uninformative Clinical Trials – JAMA (free)
“An uninformative trial is one that provides results that are not of meaningful use for a patient, clinician, researcher, or policy maker.”
Meta-Analysis: Impact of Furosemide on Mortality and the Requirement for Renal Replacement Therapy in Acute Kidney Injury
26 Jul, 2019 | 00:45h | UTC
Randomized Trial: Proton Pump Inhibitor Not Effective for Prevention of Gastroduodenal Events in Patients Receiving Low-dose Anticoagulation and/or Aspirin
26 Jul, 2019 | 00:44h | UTC
[Abstract Only] Meta-Analysis: Catheter Ablation Improves Outcomes in Patients with Atrial Fibrillation Complicated with Heart Failure
26 Jul, 2019 | 00:29h | UTCRhythm control for patients with atrial fibrillation complicated with heart failure in the contemporary era of catheter ablation: a stratified pooled analysis of randomized data – European Heart Journal (link to abstract – $ for full-text)
Commentary: Rhythm Control for Atrial Fibrillation With Heart Failure – American College of Cardiology (free)
Related Meta-Analysis: Catheter Ablation for Atrial Fibrillation Improves Outcomes in Heart Failure with Reduced Ejection Fraction (free)
Systematic Review: Interventions for Preventing Obesity in Children
26 Jul, 2019 | 00:32h | UTCInterventions for preventing obesity in children – Cochrane Library (free)
Summary: Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? – Cochrane Library (free)