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Daily Archives: April 19, 2019

Guidelines for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke

19 Apr, 2019 | 08:40h | UTC

2019 Update of the Korean Clinical Practice Guidelines of Stroke for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke – Journal of Stroke (free PDF)

Related: Guideline: Indications for Thrombectomy in Acute Ischemic Stroke from Emergent Large Vessel Occlusion (free guidelines)

 


Cochrane Review: Nicotine Replacement for Smoking Cessation More Successful in Combination Form

19 Apr, 2019 | 08:42h | UTC

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)

Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)

 

Related Commentary on Twitter

 


Meta-Analysis: Accuracy of Patient Health Questionnaire-9 (PHQ-9) for Screening to Detect Major Depression

19 Apr, 2019 | 08:39h | UTC

Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis – The BMJ (free)

Commentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)

 


Fri April 19 – 10 Stories of The Day!

19 Apr, 2019 | 08:45h | UTC

 

1 – Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)

Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)

 

2 – 2019 Update of the Korean Clinical Practice Guidelines of Stroke for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke – Journal of Stroke (free PDF)

Related: Guideline: Indications for Thrombectomy in Acute Ischemic Stroke from Emergent Large Vessel Occlusion (free guidelines)

 

3 – Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis – The BMJ (free)

Commentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)

 

4 – A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial – European Heart Journal (free)

Commentaries: Diabetes drug Metformin may fight heart disease, study says – UPI (free) AND Diabetic drug shown to reduce the risk of heart disease in non-diabetic patients – University of Dundee (free) AND Metformin reduces left ventricular mass in nondiabetic patients with CAD – Cardiovascular Business (free)

 

5 – Part-revived pig brains raise slew of ethical quandaries – Nature (free)

Original Study: Restoration of brain circulation and cellular functions hours post-mortem – Nature (free)

See also: Pig Experiment Raises Ethical Questions Around Brain Damage – Case Western Reserve University (free) AND Scientists: We kept pig brains alive 10 hours after death. Bioethicists: “Holy shit.” – Vox (free) AND The pigs were dead. But four hours later, scientists restored cellular functions in their brains – STAT (free) AND Scientists Partly Restore Activity in Dead-Pig Brains – The Atlantic (free)

 

6 – Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)

Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)

Related Review: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free)

 

7 – Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): An update in 2019 – Allergology International (free)

 

8 – Management of Hypertension in Chronic Kidney Disease – Drugs (free)

 

9 – Treatment patterns among de-novo metastatic cancer patients who died within one month of diagnosis – JNCI Cancer Spectrum (free)

Commentaries: Some patients with imminently fatal cancer still receive treatment – eCancer News (free) AND With Weeks to Live, Many Cancer Patients Try Useless Treatments – HealthDay (free)

 

10 – Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study – Journal of the American Heart Association (free)

Editorial: Perils of Observational Data Analyses (free)

Commentary: Statins for primary prevention: do benefits outweigh DM risk? – Univadis (free registration required)

Related: Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)

 


Small Randomized Trial Suggests Metformin May be Effective for Left Ventricular Hypertrophy in Patients with Coronary Artery Disease Without Diabetes

19 Apr, 2019 | 08:37h | UTC

A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes: the MET-REMODEL trial – European Heart Journal (free)

Commentaries: Diabetes drug Metformin may fight heart disease, study says – UPI (free) AND Diabetic drug shown to reduce the risk of heart disease in non-diabetic patients – University of Dundee (free) AND Metformin reduces left ventricular mass in nondiabetic patients with CAD – Cardiovascular Business (free)

 


Part-revived Pig Brains Raise Slew of Ethical Quandaries

19 Apr, 2019 | 08:35h | UTC

Part-revived pig brains raise slew of ethical quandaries – Nature (free)

Original Study: Restoration of brain circulation and cellular functions hours post-mortem – Nature (free)

See also: Pig Experiment Raises Ethical Questions Around Brain Damage – Case Western Reserve University (free) AND Scientists: We kept pig brains alive 10 hours after death. Bioethicists: “Holy shit.” – Vox (free) AND The pigs were dead. But four hours later, scientists restored cellular functions in their brains – STAT (free) AND Scientists Partly Restore Activity in Dead-Pig Brains – The Atlantic (free)

 


Management of Hypertension in Chronic Kidney Disease

19 Apr, 2019 | 08:28h | UTC

Management of Hypertension in Chronic Kidney Disease – Drugs (free)

 


Hypertension in Pregnancy: Pathophysiology and Treatment

19 Apr, 2019 | 08:33h | UTC

Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)

Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)

Related Review: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free)

 


Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus

19 Apr, 2019 | 08:25h | UTC

Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study – Journal of the American Heart Association (free)

Editorial: Perils of Observational Data Analyses (free)

Commentary: Statins for primary prevention: do benefits outweigh DM risk? – Univadis (free registration required)

Related: Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)

 


Review: Drug-induced Hypersensitivity Syndrome (DiHS)/Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

19 Apr, 2019 | 08:31h | UTC

Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): An update in 2019 – Allergology International (free)

 


Study: Aggressive Treatment Common in Patients with Imminently Fatal de Novo Metastatic Cancer

19 Apr, 2019 | 08:26h | UTC

Treatment patterns among de-novo metastatic cancer patients who died within one month of diagnosis – JNCI Cancer Spectrum (free)

Commentaries: Some patients with imminently fatal cancer still receive treatment – eCancer News (free) AND With Weeks to Live, Many Cancer Patients Try Useless Treatments – HealthDay (free)

 


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