Daily Archives: March 17, 2019
Randomized Trial: Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation
17 Mar, 2019 | 19:10h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial – JAMA (free for a limited period)
Related Study: Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial – JAMA (free for a limited period)
Video Summary: Catheter Ablation vs Drug Therapy for Patients With Atrial Fibrillation: The CABANA Trial (free)
Editorial: Catheter Ablation for Atrial Fibrillation: Lessons Learned From CABANA (free for a limited period)
Commentary: Surgery no better than medication at preventing serious complications of atrial fibrillation – NIH News Releases (free)
Related Commentary on Twitter
BREAKING: In the CABANA Trial, catheter ablation was no different from drug therapy at reducing death, disabling stroke, serious bleeding, or cardiac arrest in patients with symptomatic atrial fibrillation https://t.co/Wg0EScwrHB #ACC19 #Afib pic.twitter.com/k9CKjuQMNp
— JAMA (@JAMA_current) March 15, 2019
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
17 Mar, 2019 | 21:48h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Guideline Hub: Primary Prevention of Cardiovascular Disease (free resources)
Executive Summary: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free PDF)
Guidelines Made Simple: A Selection of Tables and Figures (free PDF)
Summary with Key Points to Remember: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease – American College of Cardiology (free)
Randomized Trial: Transcatheter Aortic-Valve Replacement vs. Surgical Aortic-Valve Replacement in Low-Risk Patients
17 Mar, 2019 | 19:08h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients – New England Journal of Medicine (free for a limited period)
Commentary: In study, TAVR is superior to surgery for low-risk patients with aortic valve stenosis – Columbia University Irving Medical Center (free)
“”The main limitation of the study is that the current results reflect outcomes after one year, which isn’t long enough to assess the long-term durability of the replacement valve,” said Leon. “Patients in the study will be followed for at least 10 years so that we can measure their long-term outcomes and inform the medical community.” (from Columbia University)
Patient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference
17 Mar, 2019 | 18:57h | UTCPatient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference – JAMA (free for a limited period)
Study: Apple Watch Can Spot Atrial Fibrillation, But More Research is Needed
17 Mar, 2019 | 18:59h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
See also: Beware the hype over the Apple Watch heart app. The device could do more harm than good – STAT (free) AND Apple Watch may spot heart problem but more research needed – Associated Press (free) AND Apple Watch May Detect A-fib in the General Population, but at What Cost? – TCTMD (free)
Related: Editorial: Downsides of Detecting Atrial Fibrillation in Asymptomatic Patients (free) AND USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended (free Guideline and commentaries) AND Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers? (free commentaries) AND Get Ready For A Tsunami Of ECGs (free commentaries)
Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction
17 Mar, 2019 | 18:58h | UTCCommentaries: Evaluate Troponin Results Carefully, Researchers Warn – NEJM Journal Watch (free) AND Blood test to diagnose heart attacks is flawed, warn researchers – The BMJ (free) AND CHARIOT: 1 in 20 Hospitalized Patients Undergoing Blood Tests Have Elevated Troponin – TCTMD (free)
Related: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)
Related Commentary on Twitter
This study found that the true 99th centile of high sensitivity cardiac troponin for a general hospital population was not consistent with the manufacturer's recommended upper limit of normal #BMJResearch @NickCurzen https://t.co/IQy62VenOx
— The BMJ (@bmj_latest) March 15, 2019
Review: Acute Respiratory Distress Syndrome
17 Mar, 2019 | 18:56h | UTCAcute Respiratory Distress Syndrome – Nature Reviews Disease Primer (free PDF)
Related Commentary on Twitter
Our article today "Acute respiratory distress syndrome" in Nature Reviews Disease Primer.
To access, click https://t.co/HWS7zqu0EAA privilege to work with M Matthay, R Zemans, G Zimmerman, J Beitler, A Mercat, M Herridge, A Randolph and C Calfee@kaimrc_ksa @KSAU_HS @NGHAnews pic.twitter.com/DMsKh0DbbC
— Yaseen Arabi (@YaseenarabiYa) March 14, 2019
Randomized Trial: An Environmental Cleaning Bundle and Health-care-associated Infections in Hospitals
17 Mar, 2019 | 18:54h | UTCAn environmental cleaning bundle and health-care-associated infections in hospitals (REACH): a multicentre, randomised trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: Hospital cleaning trial cuts infections – Queensland University of Technology (free)
Randomized Trial: Chlorhexidine vs. Routine Bathing to Prevent Multidrug-resistant Organisms and All-cause Bloodstream Infections in General Medical and Surgical Units
17 Mar, 2019 | 18:53h | UTCChlorhexidine versus routine bathing to prevent multidrug-resistant organisms and all-cause bloodstream infections in general medical and surgical units (ABATE Infection trial): a cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Results of Trial to Stem Hospital-Acquired Bacterial Infections Published – NIAID (free) Quick Take: Chlorhexidine Versus Routine Bathing to Prevent Multidrug-Resistant Organisms and All-Cause Bloodstream Infections in General Medical and Surgical Units (ABATE Infection Trial) – 2 Minute Medicine (free) AND Infection control technique may reduce infections in patients with catheters, drains – Rush University Medical Center (free)
“Decolonisation with universal chlorhexidine bathing and targeted mupirocin for MRSA carriers did not significantly reduce multidrug-resistant organisms in non-critical-care patients.”
Guideline: Management of Epithelial Precancerous Conditions and Lesions in the Stomach
17 Mar, 2019 | 18:27h | UTC
Medical Student Mentoring Programs: Current Insights
17 Mar, 2019 | 18:28h | UTCMedical student mentoring programs: current insights – Advances in Medical Education and Practice (free)
Cohort Study: Associations of Dietary Cholesterol or Egg Consumption with Incident Cardiovascular Disease and Mortality
17 Mar, 2019 | 18:50h | UTCAssociations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality – JAMA (free for a limited period)
Commentaries: Are Eggs Good Or Bad? How You Should Interpret This Latest Study – Forbes (free) AND Are eggs good or bad for you? New research rekindles the debate – STAT (free) AND Eggs are bad – then good – then bad again? What gives? – Diet Doctor (free)
Related Commentary on Twitter
Disagrees with several notable papers:
In NHS & HPFS, eggs not assoc w MI or stroke. https://t.co/F1OcIr0GjZ
In China Kadoorie study, eggs assoc w LOWER risk of CVD.https://t.co/MX6NTPfdhJ
Meta analysis: eggs assoc w LOWER stroke, no assoc w MI.https://t.co/UOFLKBw8dv https://t.co/oX6I6uvXaa
— Andrew Mente, PhD (@andrewmente) March 15, 2019
Systematic Review: Conventional Therapy for Moderate to Severe Inflammatory Bowel Disease
17 Mar, 2019 | 18:25h | UTC
Guidelines for the Management of Patients with Metastatic Esophageal Cancer
17 Mar, 2019 | 18:25h | UTC
Meta-Analysis: Benefits and Harms of Spinal Manipulative Therapy for the Treatment of Chronic Low Back Pain
17 Mar, 2019 | 18:22h | UTC
Guidelines for the Management of Patients with Metastatic Gastric Cancer
17 Mar, 2019 | 18:26h | UTC
Expert Consensus: Recommendations for the Follow-up of Children with Leg Length Discrepancy
17 Mar, 2019 | 18:23h | UTC
Overuse Injuries in Sport: A Comprehensive Overview
17 Mar, 2019 | 18:24h | UTCOveruse injuries in sport: a comprehensive overview – Journal of Orthopaedic Surgery and Research (free)
Systematic Review: Machine Perfusion Preservation vs. Static Cold Storage for Deceased Donor Kidney Transplantation
17 Mar, 2019 | 18:20h | UTCMachine perfusion preservation versus static cold storage for deceased donor kidney transplantation – Cochrane Library (free)
Perspective: Why AI Will Make Healthcare Personal
17 Mar, 2019 | 18:18h | UTCWhy AI will make healthcare personal – World Economic Forum (free)
Meta-Analysis: Mode of Delivery and Preterm Birth in Subsequent Births
17 Mar, 2019 | 18:21h | UTC“A previous cesarean section could increase the risk of preterm birth in subsequent pregnancies”
3 Ways AI is Already Changing Medicine
17 Mar, 2019 | 18:16h | UTC3 ways AI is already changing medicine – Vox (free)
Clinical Management Guidelines for Hidradenitis Suppurativa
17 Mar, 2019 | 18:19h | UTCNorth American Clinical Management Guidelines for Hidradenitis Suppurativa: a Publication from the United States and Canadian Hidradenitis Suppurativa Foundations.
Part I: Diagnosis, Evaluation, and the use of Complementary and Procedural Management (free PDF)
Part II: Topical, Intralesional, and Systemic medical Management (free PDF)
Review: Perioperative Management of the Diabetic Patient Referred to Cardiac Surgery
17 Mar, 2019 | 18:16h | UTC
Position Statement: Laser Treatment of Hyperpigmented Lesions
17 Mar, 2019 | 18:18h | UTC