Daily Archives: March 7, 2019 | LinksMedicus Free Medical News & Perspectives

Expert Consensus: Parenteral Provision of Micronutrients to Adult Patients

7 Mar, 2019 | 13:15h | UTC

Parenteral Provision of Micronutrients to Adult Patients: An Expert Consensus Paper – Journal of Parenteral and Enteral Nutrition (free)

Opinion: “Let’s Help People Live Successfully to the End of Their Lives”

7 Mar, 2019 | 13:03h | UTC

Let’s help people live successfully to the end of their lives – The BMJ (free)

“we do need to challenge the prevailing dogma of “prevention at all costs”—and create a broader vision of how to help people live successfully to the very end of their lives”

Opinion: The A.I. Diet

7 Mar, 2019 | 13:14h | UTC

The A.I. Diet – The New York Times (10 articles per month are free)

“Forget government-issued food pyramids. Let an algorithm tell you how to eat.”

Study: Impact of Procedure Time on Outcomes of Thrombectomy for Stroke

7 Mar, 2019 | 12:58h | UTC

Impact of Procedure Time on Outcomes of Thrombectomy for Stroke – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: When Is It Time to Abandon Thrombectomy for Acute Stroke? New Clues – TCTMD (free) AND When should stroke thrombectomy be considered futile? – Cardiovascular Business (free) AND Impact of Procedure Time on Stroke Outcomes – American College of Cardiology (free)

FDA Approves Ketamine-like drug for Treatment-resistant Depression

7 Mar, 2019 | 12:44h | UTC

FDA approves new nasal spray medication for treatment-resistant depression; available only at a certified doctor’s office or clinic – U.S. Food & Drug Administration (free)

Commentaries: A ketamine-like drug is the first new antidepressant to get FDA approval in years: But it’s also controversial. – Vox (free) AND FDA Approves Intranasal Esketamine as Adjunctive Treatment for Depression – NEJM Journal Watch (free)

“But while some patient and doctor groups are hailing the approval, others aren’t so sure there’s enough evidence to justify it. That’s because the benefits of ketamine and esketamine aren’t yet well-understood. According to the FDA, the drug has only been studied in four clinical trials, three of them lasting just four weeks. And the results were pretty mixed.” (from Vox)

Related Commentary on Twitter

#FDA never learns from its past mistakes.
20 yrs ago, approved #Oxycontin, supposedly w restrictions.
We know how well those safety checks worked.
Now same blindness to risks of promoting #esketamine.
Doesnt it know people with #Depression will self medicate with street Special K https://t.co/FEj8S4QIFw

— Allen Frances (@AllenFrancesMD) March 6, 2019

Meta-Analysis: Patient Relevant Outcomes of Unicompartmental vs. Total Knee Replacement

7 Mar, 2019 | 12:50h | UTC

Patient relevant outcomes of unicompartmental versus total knee replacement: systematic review and meta-analysis – The BMJ (free)

Commentary: Pros and cons of knee replacement options reviewed – Medwire News (free)

Report: Artificial Intelligence in Healthcare

7 Mar, 2019 | 11:45h | UTC

Artificial Intelligence in healthcare – Academy of Medical Royal Colleges (free PDF)

Commentaries: Report warns of AI healthcare limitations – HealthManagement.org (free) AND Academy of Medical Royal Colleges publishes report looking at the predicted impact of Artificial Intelligence – The Royal College of Ophthalmologists (free)

Thu, March 7 – 10 Stories of The Day!

7 Mar, 2019 | 03:23h | UTC

1 – NICE Guideline: Intrapartum care for women with existing medical conditions or obstetric complications and their babies – National Institute for Health and Care Excellence (free)

2 – β-blockers after acute myocardial infarction in patients with chronic obstructive pulmonary disease: A nationwide population-based observational study – PLOS One (free)

Related: Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization (free study and reviews on the subject) AND β‐Blocker Use and Mortality in COPD Patients After Myocardial Infarction: A Swedish Nationwide Observational Study (free – similar study from Sweden)

Source: Hospital Medicine Virtual Journal Club

3 – Pre-hospital advanced airway management for adults with out-of-hospital cardiac arrest: nationwide cohort study – the BMJ (free)

Commentary: ECG rhythm and airway management make all the difference during a heart attack – Osaka University (free)

4 – Associations of statin use with glycaemic traits and incident type 2 diabetes – British Journal of Clinical Pharmacology (free PDF)

Commentaries: Statins associated with 38 per cent increased risk of type 2 diabetes – Diabetes.co.uk (free) AND Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes – News Medical (free)

5 – Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review – JAMA (free for a limited period)

Podcast: COPD: All You Need to Know in 20 Minutes – JAMA (free)

6 – An ultrasound scan is not as useful as a CT scan in assessing trauma – NIHR Signal (free)

Original Article: Point‐of‐care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma – Cochrane Library (free)

7 – Choosing Wisely Canada: Five Things Physicians and Patients Should Question in Otolaryngology – Rhinology – Canadian Society of Otolaryngology – Head & Neck Surgery (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

8 – Inclusion body myositis: clinical features and pathogenesis – Nature Reviews Rheumatology (free)

9 – What do the people of the world die from? – BBC (free)

10 – The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births – PLOS Medicine (free)

Commentaries: Study confirms and quantifies Zika-microcephaly link in Brazil – PLOS (free) AND Study highlights early pregnancy Zika microcephaly risk – CIDRAP (free)

Review: From Big Data to Precision Medicine

7 Mar, 2019 | 11:44h | UTC

From Big Data to Precision Medicine – Frontiers in Medicine (free)

NICE Guideline: Intrapartum Care for Women with Existing Medical Conditions or Obstetric Complications and Their Babies

7 Mar, 2019 | 03:01h | UTC

NICE Guideline: Intrapartum care for women with existing medical conditions or obstetric complications and their babies – National Institute for Health and Care Excellence (free)

Nationwide Cohort Study Suggests Different Airway Management Strategies for Adults with Out-of-hospital Cardiac Arrest Based on Initial Electrocardiographic Rhythm

7 Mar, 2019 | 02:53h | UTC

Pre-hospital advanced airway management for adults with out-of-hospital cardiac arrest: nationwide cohort study – the BMJ (free)

Commentary: ECG rhythm and airway management make all the difference during a heart attack – Osaka University (free)

Related Commentary on Twitter

Is pre-hospital advanced airway management associated with improved outcomes after out-of-hospital cardiac arrest? This study of 310 620 adults found that results differed according to each patient’s first documented electrocardiographic rhythm https://t.co/ZamSVHpL1R pic.twitter.com/a9U7rRugvo

— The BMJ (@bmj_latest) March 3, 2019