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Daily Archives: November 9, 2018

Guideline Synopsis: Incidental Pulmonary Nodules Detected on CT Images

9 Nov, 2018 | 03:00h | UTC

Incidental Pulmonary Nodules Detected on CT Images – JAMA (free)

 


WHO Guideline: Management of Physical Health Conditions in Adults with Severe Mental Disorders

9 Nov, 2018 | 03:02h | UTC

Guideline: Management of physical health conditions in adults with severe mental disorders – World Health Organization (free PDF)

News Release: WHO guidelines: Management of physical health conditions in adults with severe mental disorders (free)

WHO Video: Improving the physical health of people with severe mental disorders (free)

 


Randomized Trial: New Single-Dose Oral Drug for Treatment of Gonorrhea

9 Nov, 2018 | 02:56h | UTC

Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea – New England Journal of Medicine (link to abstract – $ for full-text)

Related Perspective: Neisseria gonorrhoeae — Rising Infection Rates, Dwindling Treatment Options – New England Journal of Medicine (free)

Commentaries: Novel antibiotic shows promise in treatment of uncomplicated gonorrhea – NIH News Release (free) AND Experimental treatment appears effective against gonorrhea in small study – STAT (free) AND Single Dose of New Oral Antibiotic Cures Most Gonorrhea – Medscape (free registration required)

 


Randomized Trial: Triple-Drug Treatment for Lymphatic Filariasis

9 Nov, 2018 | 02:58h | UTC

A Trial of a Triple-Drug Treatment for Lymphatic Filariasis – New England Journal of Medicine (free)

Editorial: Advancing toward the Elimination of Lymphatic Filariasis (free)

Commentary: Triple-Drug Therapy Superior to Two Drugs for Treating Lymphatic Filariasis – NEJM Journal Watch (free)

 


Randomized Trial: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

9 Nov, 2018 | 02:55h | UTC

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome – New England Journal of Medicine (free)

Commentaries: Among heart attack survivors, drug reduces chances of second heart attack or stroke – University of Colorado Anschutz Medical Campus (free) AND Alirocumab Linked to Lower Risk for Recurrent Ischemic CV Events – NEJM Journal Watch (free)

“An estimated 49 patients would need to be treated for 4 years to prevent one CV event.” (from NEJM Journal Watch)

 


Review: Gastroesophageal Reflux Disease, Functional Dyspepsia and Irritable Bowel Syndrome

9 Nov, 2018 | 02:53h | UTC

Gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome: common overlapping gastrointestinal disorders – Annals of Gastroenterology (free)

 


Debate: Could AI Make Doctors Obsolete?

9 Nov, 2018 | 02:51h | UTC

Head To Head: Could artificial intelligence make doctors obsolete? – The BMJ (free)

Commentaries: Could machines using artificial intelligence make doctors obsolete? – The BMJ (free) AND Stop hyping artificial intelligence—patients will always need human doctors – The BMJ (free)

 


Study: Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis

9 Nov, 2018 | 02:50h | UTC

A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain – Radiology (free for a limited period)

Commentaries: Artificial intelligence predicts Alzheimer’s years before diagnosis – Radiology Society of North America (free) AND Expert reaction to study looking at AI technology, brain imaging and Alzheimer’s disease detection – Science Media Centre (free) AND AI May Detect Alzheimer’s Years Before Diagnosis – Medscape (free registration required)

 


Meta-Analysis: Triple Therapy in the Management of COPD

9 Nov, 2018 | 02:46h | UTC

Triple therapy in the management of chronic obstructive pulmonary disease: systematic review and meta-analysis – The BMJ (free)

Commentary: Triple Therapy for COPD Tied to Fewer Exacerbations, More Pneumonia – NEJM Journal Watch (free)

 


Perspective: Why Doctors Hate Their Computers

9 Nov, 2018 | 02:42h | UTC

Why Doctors Hate Their Computers – The New Yorker (free)

“Digitization promises to make medical care easier and more efficient. But are screens coming between doctors and patients?”

 


In Win for Open Access, Two Major Funders Won’t Cover Publishing in Hybrid Journals

9 Nov, 2018 | 02:40h | UTC

In win for open access, two major funders won’t cover publishing in hybrid journals – Science (free)

See also: Wellcome and Gates join bold European open-access plan – Nature (free) AND Wellcome is updating its open access policy (free) AND Big funders back plan for instant free access to journals, but researchers say it is risky for science – Science|Business (free)

Related: cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)

 


WHO Guide: Basic Emergency Care

9 Nov, 2018 | 02:44h | UTC

Basic Emergency Care: approach to the acutely ill and injured – World Health Organization (free PDF)

 


Study: Health-Motivated Taxes on Red and Processed Meat

9 Nov, 2018 | 02:36h | UTC

Health-motivated taxes on red and processed meat: A modelling study on optimal tax levels and associated health impacts – PLOS One (free)

Commentaries: Should there be a tax on red meat? – BBC (free) AND Taxing red meat would save many lives, research shows – The Guardian (free)

Related: To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Policy lessons from health taxes (free research and commentaries) AND Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND The Lancet taskforce on NCDs and economics (free series and commentaries)

 


Podcast: Battle of the Heart Societies: Who Is Right–the US or Europe–Regarding How to Manage Hypertension?

9 Nov, 2018 | 02:27h | UTC

Battle of the Heart Societies: Who Is Right–the US or Europe–Regarding How to Manage Hypertension? – JAMA (free)

Related: Impact of the Discordance Between Blood Pressure Guidelines (free perspective and commentaries)

 


Study: Link Between Vaccines and Allergies Dismissed

9 Nov, 2018 | 02:32h | UTC

Vaccination and Allergic Sensitization in Early Childhood – The ALADDIN Birth Cohort – EClinicalMedicine (free)

Commentary: Link between vaccines and allergies dismissed – Karolinska Institutet (free)

 


2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay

9 Nov, 2018 | 02:36h | UTC

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay (free)

See also: Executive Summary (free) AND Summary form AAC (free) AND Bradycardia Guideline Hub (free resources)

 


Guideline Summary: Prevention, Diagnosis and Treatment of Hospital-Acquired Pneumonia in ICU

9 Nov, 2018 | 02:20h | UTC

Brief summary of French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU – Annals of Intensive Care (free)

Related: Summary of the international clinical guidelines for the management of hospital-acquired and ventilator-acquired pneumonia (free) AND International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia (free) AND Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society (free)

 


Clinical Practice Guidelines for Quality Palliative Care

9 Nov, 2018 | 02:22h | UTC

Clinical Practice Guidelines for Quality Palliative Care, 4th Edition – National Consensus Project’s (free)

News Release: New National Guidelines Seek to Improve Access to Palliative Care for People Living with Serious Illness (free)

Commentaries: Palliative care guidelines updated with increased focus on collaboration, communication – ACP Internist (free) AND New Palliative Care Guidelines Demand ‘Seismic Shift’ in Care – Medscape (free registration required)

 


Systematic Review: Reduced Salt Intake for Heart Failure

9 Nov, 2018 | 02:19h | UTC

Reduced Salt Intake for Heart Failure: A Systematic Review – JAMA Internal Medicine (free for a limited period)

Commentaries: Sodium Restriction in Heart Failure: Too Much Uncertainty—Do the Trials – JAMA Internal Medicine (free for a limited period) AND Review Questions Wisdom of Limiting Salt Intake in Heart Failure – NEJM Journal Watch (free) AND Review: Low-Sodium Diet for HF on Shaky Ground – MedPage Today (free registration required)

 


Meta-analysis: Off‐ Versus On‐Pump Coronary Surgery and the Effect of Follow‐Up Length and Surgeons’ Experience

9 Nov, 2018 | 02:07h | UTC

Off‐ Versus On‐Pump Coronary Surgery and the Effect of Follow‐Up Length and Surgeons’ Experience: A Meta‐Analysis – Journal of the American Heart Association (free)

Editorial: Long‐Term Survival Following Off‐Pump Coronary Surgery: Does Surgeon Experience Make a Difference? (free)

 


Study: One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory

9 Nov, 2018 | 02:02h | UTC

One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory – Journal of Clinical Psychiatry (link to abstract – $ for full-text)

Commentaries: When Adolescents Give Up Pot, Their Cognition Quickly Improves – NPR (free) AND Stopping Cannabis Tied to Memory Improvements – NEJM Journal Watch (free)

 


Meta-Analysis: Diagnostic Value of Symptoms and Signs for Identifying UTI in Older adults

9 Nov, 2018 | 02:05h | UTC

Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: Systematic review and meta-analysis – The Journal of Infection (free)

“A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients.”

 


Perspective: A Profusion of Diagnoses. That’s Good and Bad

9 Nov, 2018 | 02:17h | UTC

A Profusion of Diagnoses. That’s Good and Bad – The New York Times (10 articles per month are free)

“…we may also be medicalizing much of normal human behavior — labeling the healthy as diseased, and exposing them to undue risk of stigma, testing and treatment.”

 


Systematic Review: Supplements for Preventing Cognitive Decline in People with Mild Cognitive Impairment

9 Nov, 2018 | 01:59h | UTC

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)

Summary: Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment – Cochrane Library (free)

“The evidence on vitamin and mineral supplements as treatments for MCI is very limited. “

 


Study: E-cigarette Use and Subsequent Smoking Frequency Among Adolescents

9 Nov, 2018 | 02:00h | UTC

E-cigarette Use and Subsequent Smoking Frequency Among Adolescents – Pediatrics (free)

Commentary: E-cigarette users have greater odds of subsequent cigarette use – 2 Minute Medicine (free)

“Among adolescent never smokers, electronic cigarette (e-cigarette) users had approximately 4-fold greater odds of initiating cigarette use at follow-up 2-3 years later.” (from 2 Minute Medicine)

 


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