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Daily Archives: September 14, 2018

AHA Guideline: Resistant Hypertension

14 Sep, 2018 | 02:31h | UTC

Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association – Hypertension (free PDF)

News Release: Diagnosing and treating resistant hypertension (free)

Commentaries: Tackling Resistant Hypertension – Opportunities and Challenges (free) AND Heart Group Updates Guidelines on Resistant Hypertension – Physician’s First Watch (free)

Top Ten Things to Know: Resistant Hypertension: Detection, Evaluation, and Management (free PDF)


Cohort Study: Elevated Blood Pressure and Risk of Aortic Valve Disease

14 Sep, 2018 | 02:30h | UTC

Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults – European Heart Journal (free)

Commentary: Elevated blood pressure is linked to increased risk of aortic valve disease – European Society of Cardiology (free)


Systematic Review: Are Invasive Procedures Effective for Chronic Pain?

14 Sep, 2018 | 02:28h | UTC

Are Invasive Procedures Effective for Chronic Pain? A Systematic Review – Pain Medicine (free)

Commentaries: New study questions effectiveness of invasive procedures for chronic pain – The Reis Group (free) AND Invasive Procedures For Chronic Pain Have Not Been Proven to Work – (free)

Related: Needless procedures: knee arthroscopy is one of the most common but least effective surgeries – The Conversation (free)


Report: Global Cancer Statistics 2018

14 Sep, 2018 | 02:29h | UTC

Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries – CA: A Cancer Journal for Clinicians (free)

See also: Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018 – International Agency for Research on Cancer (free PDF)

Infographic: Global Cancer Data 2018 (free)

Commentaries: WHO: 9.6 million cancer deaths, 18 million new cases this year – UPI (free) AND Cancer will kill nearly 10 million people this year, report estimates – CNN (free) AND Cancer deaths rise to 9.6 million as populations grow and age – Reuters (free)


The New ECG Apple Watch Could do More Harm Than Good

14 Sep, 2018 | 02:27h | UTC

The New ECG Apple Watch Could do More Harm Than Good – Wired (a few articles per month are free) (via @EricTopol)

See also: New Watch can Help Doctors Monitor your Heart in Real Time (free commentaries)


Perspective: What 21st Century Health Care Should Learn from 20th Century Business

14 Sep, 2018 | 02:28h | UTC

What 21st Century Health Care Should Learn from 20th Century Business – NEJM Catalyst (free)


Opinion – Scientific Publishing is a Rip-off. We Fund the Research – It Should be Free

14 Sep, 2018 | 02:26h | UTC

Scientific publishing is a rip-off. We fund the research – it should be free – The Guardian (free)

Related: cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)


Thousands of Scientists Publish a Paper Every Five Days

14 Sep, 2018 | 02:25h | UTC

Thousands of scientists publish a paper every five days – Nature (free)

Related: Some scientists publish more than 70 papers a year. Here’s how—and why—they do it – Science (free)


Cohort Study: Effect of Mammography Screening on Breast Cancer Mortality

14 Sep, 2018 | 02:25h | UTC

Effect of organised mammography screening on breast cancer mortality: A population‐based cohort study in Norway – International Journal of Cancer (free)

Commentaries: Breast cancer screening does not reduce mortality – eCancer News (free) AND Danish study attributes improved treatment, not screening, to decline in breast cancer deaths – Health Imaging (free)


Meta-Analysis: Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors

14 Sep, 2018 | 02:22h | UTC

Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis – JAMA Oncology (free for a limited period)

Commentaries: Study Discerns Rare Risks of Fatal Side Effects From Cancer Immunotherapy – AJMC (free) AND Fatal Toxicities Rare With Checkpoint Inhibitors – (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)


NICE Guideline: Chronic Heart Failure in Adults

14 Sep, 2018 | 02:20h | UTC

Chronic heart failure in adults: diagnosis and management – National Institute for Health and Care Excellence (free)


FDA Takes New Steps to Address Epidemic of Youth E-Cigarette Use

14 Sep, 2018 | 02:07h | UTC

FDA takes new steps to address epidemic of youth e-cigarette use, including a historic action against more than 1,300 retailers and 5 major manufacturers for their roles perpetuating youth access (free)

Commentaries: FDA: we might have to ban some e-cigarettes to stop teens from vaping – VOX (free) AND FDA Intensifies Crackdown On E-Cigarette Sales To Teenagers – NPR (free)

“The agency is eyeing a crackdown on flavored e-cigs in the face of an “epidemic” of teen use.” (from VOX)


Review: Arterial Hypertension

14 Sep, 2018 | 02:18h | UTC

Arterial Hypertension: Diagnosis and treatment – Deutsches Ärzteblatt international (free)


European Union Standards for Tuberculosis Care

14 Sep, 2018 | 02:19h | UTC

European Union Standards for Tuberculosis Care – European Centre for Disease Prevention and Control (free PDF in several languages) (via @ECDC_TB and @Onisillos)


USPSTF Draft Statement: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum

14 Sep, 2018 | 02:16h | UTC

USPSTF Draft Recommendation Statement: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum (free)

Commentaries: USPSTF Again Recommends Ointment to Prevent Gonococcal Eye Infection in Newborns – Physician’s First Watch (free) AND USPSTF Reaffirms Ocular Prophylaxis for All Newborns – MedPage Today (free)


Overdiagnosis: Causes and Consequences in Primary Health Care

14 Sep, 2018 | 02:09h | UTC

Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) (via @cantaskforce)

Related: Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF)


Meta-Analysis: Restrictive vs. Liberal Transfusion Strategies in Cardiac Surgery

14 Sep, 2018 | 02:07h | UTC

Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis – European Heart Journal (free)

Related study: Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery (link to abstract)


Study: Factors Associated With Long-term Benzodiazepine Use Among Older Adults

14 Sep, 2018 | 02:04h | UTC

Factors Associated With Long-term Benzodiazepine Use Among Older Adults – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: 1 in 4 Older Adults Prescribed a Benzodiazepine Goes on to Risky Long-Term Use, Study Finds – Michigan Medicine, via NewsWise (free) AND Long-Term Benzodiazepine Use Common Among Older Adults – Physician’s First Watch (free) AND Factors Predicting Long-term Benzodiazepine Use Identified – Medscape (free registration required) AND Larger Number of Benzodiazepine Pills in Initial Prescription Associated With Long Term Use – (free)

Related: A Quiet Drug Problem Among the Elderly – The New York Times (free) AND Our Other Prescription Drug Problem – New England Journal of Medicine (free) AND Benzodiazepines: our other prescription drug epidemic – STAT (free) AND Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free)


Report: Egg Freezing in Fertility Treatment Trends and Figures

14 Sep, 2018 | 02:06h | UTC

Egg freezing in fertility treatment Trends and figures: 2010-2016 – Human Fertilisation and Embryology Authority (HFEA) (free PDF)

Press release: Age is the key factor for egg freezing success says new HFEA report, as overall treatment numbers remain low (free)

Commentaries: Expert reaction to HFEA report on trends in egg freezing – Science Media Centre (free) AND Freeze eggs before 35 for a better chance of IVF success, says report – The Guardian (free)


Randomized Trial: Piperacillin-Tazobactam vs for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance

14 Sep, 2018 | 02:03h | UTC

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Video Summary: Effect of Piperacillin-Tazobactam vs Meropenem on Mortality in Gram-Negative Bloodstream Infection – JAMA (free)

Commentaries: Combo antibiotic found inferior for MDR bloodstream infections – CIDRAP (free) AND Drug Combo No Better for Hard-to-Treat Bloodstream Infections – Medscape (free registration required)

“The results do not support the use of Pip/Tazo as 30 d mortality was 12.3% in Pip/Tazo vs 3.7% in Mero arms” (via @CarlosdelRio7 see Tweet)


Systematic Review: Antibiotics for Acute Rhinosinusitis in Adults

14 Sep, 2018 | 02:01h | UTC

Antibiotics for acute rhinosinusitis in adults – Cochrane Library (free for a limited period)

Summary: Antibiotics for sinus infection of short duration in adults – Cochrane Library (free)

“Considering antibiotic resistance, and the very low incidence of serious complications, we conclude there is no place for antibiotics for people with uncomplicated acute rhinosinusitis.”


Opinion: Are We Being Misled About Precision Medicine?

14 Sep, 2018 | 02:01h | UTC

Are We Being Misled About Precision Medicine? – The New York Times (10 articles per month are free)

“Doctors and hospitals love to talk about the cancer patients they’ve saved, and reporters love to write about them. But deaths still vastly outnumber the rare successes.”


Comparisons of Guidelines on Managing ANCA–Associated Vasculitis

14 Sep, 2018 | 02:00h | UTC

Comparisons of Guidelines and Recommendations on Managing Antineutrophil Cytoplasmic Antibody–Associated Vasculitis – Kidney International Reports (free)


Opinion – Screening: How Overdiagnosis and Other Harms can Undermine the Benefits

14 Sep, 2018 | 01:59h | UTC

Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free)

“All screening programs do harm, some do good as well.”


Last Month in Oncology with Dr. Bishal Gyawali: August 2018

14 Sep, 2018 | 01:58h | UTC

Last Month in Oncology with Dr. Bishal Gyawali: August 2018 – eCancer News (free)


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