Daily Archives: July 20, 2018 | LinksMedicus Free Medical News & Perspectives

Expert Reaction to Trial Looking at Adrenaline for Cardiac Arrests

20 Jul, 2018 | 03:32h | UTC

Expert reaction to trial looking at adrenaline for cardiac arrests – Science Media Centre (free)

See original article in yesterday’s issue: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest (see #1)

Systematic Review: To Continue Taking or To Stop Taking Antiplatelet Drugs Before Non-Cardiac Surgery

20 Jul, 2018 | 03:31h | UTC

To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (link to abstract – $ for full-text)

Summary: To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (free)

“We found low-certainty evidence that either continuation or discontinuation of antiplatelet therapy before non-cardiac surgery may make little or no difference to mortality, bleeding requiring surgical intervention, or ischaemic events”.

Cohort Study: Poor Air Quality Does Not Offset Exercise’s Heart Benefits

20 Jul, 2018 | 03:30h | UTC

Effects of Leisure‐Time and Transport‐Related Physical Activities on the Risk of Incident and Recurrent Myocardial Infarction and Interaction With Traffic‐Related Air Pollution: A Cohort Study – Journal of the American Heart Association (free)

Commentaries: Poor air quality does not offset exercise’s heart benefits – AHA/ASA Newsroom (free) AND Why smog should not be your excuse to skip workouts – Reuters (free)

Randomized Trial: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement

20 Jul, 2018 | 03:28h | UTC

Subacromial decompression versus diagnostic arthroscopy for shoulder impingement: randomised, placebo surgery controlled clinical trial – The BMJ (free)

Commentary: Most common shoulder operation is no more beneficial than placebo surgery – University of Helsinki, via EurekAlert (free)

Related research with similar results: Arthroscopic subacromial decompression for subacromial shoulder pain (free article, editorial and commentaries)

Randomized Trial: Glutamine to Treat Sickle Cell Disease

20 Jul, 2018 | 03:29h | UTC

A Phase 3 Trial of l-Glutamine in Sickle Cell Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Glutamine to Treat Sickle Cell Disease (free)

Commentaries: Drug may ease pain, lessen hospitalization from sickle cell disease – UPI (free)

Cohort Study: Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients with Curable Cancers

20 Jul, 2018 | 03:25h | UTC

Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers – JAMA Oncology (free for a limited period)

Commentary: Association of complementary medicine, cancer treatment, survival – eCancer News (free)

Cohort Study: Sulfonylureas as Second Line Drugs in Type 2 Diabetes and the Risk of Adverse Outcomes

20 Jul, 2018 | 03:24h | UTC

Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study – The BMJ (free)

Editorial: Sulfonylureas as second line treatment for type 2 diabetes – The BMJ (free for a limited period)

Commentaries: Diabetes: Switching to Sulfonylureas from Metformin Linked to Increased Side Effects – MedicalResearch.com (free) AND Switching diabetes patients to sulfonylurea linked with complications – Pulse (free) AND Raised risk of MI and mortality when starting sulfonylurea – OnMedica (free)

Cohort Study: Mortality Due to Cirrhosis and Liver Cancer in the United States

20 Jul, 2018 | 03:26h | UTC

Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study – The BMJ (free)

Commentaries: A Spike In Liver Disease Deaths Among Young Adults Fueled By Alcohol – NPR (free) AND Alcohol-related liver failure deaths rising among U.S. young adults – Reuters (free) AND More Americans Are Dying of Cirrhosis and Liver Cancer – The New York Times (10 articles per month are free)

Systematic Review: Omega-6 fats for the Primary and Secondary Prevention of Cardiovascular Disease

20 Jul, 2018 | 03:22h | UTC

Omega-6 fats for the primary and secondary prevention of cardiovascular disease – Cochrane Library (link to abstract – $ for full-text)

Summary: Omega-6 fats to prevent and treat heart and circulatory diseases – Cochrane Library (free)

BMJ Series: Strengthening Research for Health in the Americas

20 Jul, 2018 | 03:21h | UTC

Series: Strengthening Research for health in the Americas – The BMJ (free articles)

Editorial: Research for health in the Americas (free)

Clinical Evidence Synopsis: Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics

20 Jul, 2018 | 03:23h | UTC

Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics – JAMA (free for a limited period)

Original Article: Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children – Cochrane Library (link to abstract – $ for full-text) AND Summary: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use (free)

Systematic Review: Polyunsaturated Fatty Acids for the Primary and Secondary Prevention of Cardiovascular Disease

20 Jul, 2018 | 03:22h | UTC

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (link to abstract – $ for full-text)

Summary: Polyunsaturated fatty acids for prevention and treatment of diseases of the heart and circulation – Cochrane Library (free)

Cohort Study: Metformin and Risk of Hypertension

20 Jul, 2018 | 03:20h | UTC

Metformin and Risk of Hypertension in Taiwanese Patients With Type 2 Diabetes Mellitus – Journal of the American Heart Association (free)

“A reduced risk of hypertension is observed in metformin users in a dose‐response pattern”.

Randomized Trial: E-Counseling for Hypertension

20 Jul, 2018 | 03:07h | UTC

Randomized Controlled Trial of E-Counseling for Hypertension: REACH – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Virtual counseling helps lower blood pressure – AHA News (free) AND E-counseling can lower blood pressure, heart disease risk – Medical News Today (free)

Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease

20 Jul, 2018 | 03:18h | UTC

Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (link to abstract – $ for full-text)

Cochrane Summaries: New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death (free) AND Omega-3 intake for cardiovascular disease (free)

Commentaries: Expert reaction to Cochrane review on omega-3 fatty acids and risk of heart disease, stroke and death – Science Media Centre (free) AND Omega 3 supplements don’t protect against heart disease – new review – The Conversation (free)

Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free article and commentary)

Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest

20 Jul, 2018 | 03:19h | UTC

A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (free)

Editorial: Testing Epinephrine for Out-of-Hospital Cardiac Arrest (free)

Commentary: Using adrenaline in cardiac arrests results in less than 1 percent more people leaving hospital alive – University of Warwick, via EurekAlert (free)

See also: Infographic detailing result findings (free)

“A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive – but almost doubles the risk of severe brain damage for survivors of cardiac arrest” (from University of Warwick).