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Daily Archives: July 6, 2018

WHO Report: Low Quality Healthcare is Increasing the Burden of Illness and Health Costs Globally

6 Jul, 2018 | 09:57h | UTC

Delivering quality health services: A global imperative for universal health coverage – World Health Organization (free)

News Release: Low quality healthcare is increasing the burden of illness and health costs globally (free)

Commentary: Universal quality healthcare coverage—a commitment to building a healthier and more productive society – The BMJ Opinion (free)

Related: Handbook for national quality policy and strategy: A practical approach for developing policy and strategy to improve quality of care – World Health Organization (free)

 


Guideline: Endocrine Disorders in Survivors of Childhood Cancer

6 Jul, 2018 | 09:56h | UTC

Hypothalamic–Pituitary and Growth Disorders in Survivors of Childhood Cancer: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)

Commentaries: Up to half of childhood cancer survivors will develop hormone disorders – The Endocrine Society, via ScienceDaily (free) AND Guideline Addresses Endocrine Effects After Childhood Cancer – Medscape (free registration required)

 


Study: Risk-Stratified Screening for Breast Cancer

6 Jul, 2018 | 09:55h | UTC

Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer: A Life-Table Model – JAMA Oncology (free)

Editorial: Implementation Challenges for Risk-Stratified Screening in the Era of Precision Medicine (free)

Author Interview: Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Breast Cancer Screening (free)

Commentaries: New approach to breast cancer screening — tailoring guidelines for each patient — may save lives and money, study says – STAT (free) AND No screening is better for women with low breast cancer risk, finds study – Guardian (free) AND Breast Cancer Screening Only for Women at Higher Risk – Medscape (free registration required)

 


Review: Heart Failure with Preserved Ejection Fraction

6 Jul, 2018 | 09:54h | UTC

Heart failure with preserved ejection fraction: from mechanisms to therapies – European Heart Journal (free)

 


Review: Anemia and Iron Deficiency in Heart Failure

6 Jul, 2018 | 09:52h | UTC

Anemia and Iron Deficiency in Heart Failure: Current Concepts and Emerging Therapies – Circulation (free)

 


Perspective: Hidden Conflicts?

6 Jul, 2018 | 09:51h | UTC

Hidden conflicts? – Science Magazine (free for a limited period)

““Pay-later conflicts of interest” have gone largely unnoticed & entirely unpoliced”. (via @cpiller see Tweet)

 


Cohort Study: Direct Oral Anticoagulants vs Warfarin

6 Jul, 2018 | 09:49h | UTC

Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care – The BMJ (free)

Commentary: Analysis Finds Less Bleeding — But Potentially Greater Mortality Risk — with Some Newer Anticoagulants – NEJM Physician’s First Watch (free)

 


Study: Species-Specific Activity of Antibacterial Drug Combinations

6 Jul, 2018 | 09:48h | UTC

Species-specific activity of antibacterial drug combinations – Nature (link to abstract – $ for full-text)

Commentaries: Study: For antibiotics, good things may come in pairs – CIDRAP (free) AND Combining antibiotics alters effectiveness, study says – UPI (free) AND As drug resistance grows, combining antibiotics could turn up new treatments – STAT (free)

 


Overview of Guidelines for the Management of Non-Specific Low Back Pain in Primary Care

6 Jul, 2018 | 09:50h | UTC

Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free)

 


Randomized Trial: Antibiotic Prophylaxis for Patients with Neurogenic Bladder and Repeated Urinary Tract Infections

6 Jul, 2018 | 09:47h | UTC

Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial – The Lancet Infectious Diseases (free)

Invited Commentary: Preventing urinary tract infections in patients with neurogenic bladder (free)

 


Guideline: Antibiotic Use in Adults with Community-acquired Pneumonia

6 Jul, 2018 | 09:46h | UTC

Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia – The Korean Society of Infectious Disease (free)

Related Guideline: Pneumonia: Diagnosis and Management of Community- and Hospital-Acquired Pneumonia in Adults – National Institute for Health and Care Excellence (free)

 


Review: Management of Myocardial Infarction with Nonobstructive Coronary Arteries

6 Jul, 2018 | 09:44h | UTC

Pathophysiology, diagnosis and management of MINOCA: an update – European Heart Journal: Acute Cardiovascular Care (free)

 


Evidence-Based Approach: Evaluation and Management of the Febrile Child in the Emergency Department

6 Jul, 2018 | 09:45h | UTC

An evidence-based approach to evaluation and management of the febrile child in Indian emergency department – International Journal of Critical Illness & Injury Science (free)

 


Study: Long Work Hours Associated with Increased Risk of Diabetes

6 Jul, 2018 | 09:41h | UTC

Adverse effect of long work hours on incident diabetes in 7065 Ontario workers followed for 12 years – BMJ Open Diabetes Research & Care (free)

Commentaries: Clocking up 45+ working hours/week linked to heightened risk of diabetes in women – BMJ, via ScienceDaily (free) AND Greater Risk of Diabetes in Women With Longer Work Week – MedicalResearch.com (free)

Related Study: Effect of Work Stressors on the Risk of Type 2 Diabetes (link to abstract and commentary)

 


Review: Treatment of Angina

6 Jul, 2018 | 09:42h | UTC

Treatment of Angina: Where Are We? – Cardiology (free)

Source: Critical Care Reviews Newsletter

 


Cohort Study: Presentation, Clinical Profile, and Prognosis of Young Patients with Myocardial Infarction with Nonobstructive Coronary Arteries

6 Jul, 2018 | 09:43h | UTC

Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study – Journal of the American Heart Association (free)

Editorial: Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): It’s Time to Face Reality! (free)

 


Randomized, Crossover Trial: Lentils Reduces Postprandial Glycemic Response

6 Jul, 2018 | 09:40h | UTC

Carbohydrate Replacement of Rice or Potato with Lentils Reduces the Postprandial Glycemic Response in Healthy Adults in an Acute, Randomized, Crossover Trial – The Journal of Nutrition (link to abstract – $ for full-text)

Commentaries: Lentils significantly reduce blood glucose levels – University of Guelph, via ScienceDaily (free) AND Replace Carbs With Lentils to Blunt Glucose Spike After Meals – Medscape (free registration required)

 


Alarming Polio Outbreak Spreads in Congo, Threatening Global Eradication Efforts

6 Jul, 2018 | 09:40h | UTC

Alarming polio outbreak spreads in Congo, threatening global eradication efforts – Science (free)

 


Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain

6 Jul, 2018 | 09:37h | UTC

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis – Canadian Medical Association Journal (free)

Commentaries: Class of drugs used as alternative to opioids for back pain are ineffective, have potentially serious side effects: report – The Globe and Mail (free) AND Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing – CMAJ, via EurekAlert (free)

Related Meta-Analysis: Benefits and safety of gabapentinoids in chronic low back pain (free research and commentaries)

 


Randomized Trial: Epinephrine vs Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction

6 Jul, 2018 | 09:35h | UTC

Epinephrine Versus Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Epinephrine vs. Norepinephrine for Cardiogenic Shock – American College of Cardiology (free) AND Norepinephrine Bests Epinephrine in Battle of the Vasopressors in Cardiogenic Shock – TCTMD (free)

 


The Carbohydrate-Insulin Model of Obesity: Beyond “Calories In, Calories Out”

6 Jul, 2018 | 09:36h | UTC

The Carbohydrate-Insulin Model of Obesity: Beyond “Calories In, Calories Out” – JAMA Internal Medicine (free for a limited period)

 


Cohort Study: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease

6 Jul, 2018 | 09:39h | UTC

Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease Risk Factor Development: An Observational Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Hypertensive disorders during pregnancy associated with increased rates of later CVD – ACP Internist (free) AND High blood pressure in pregnancy tied to heart disease risk afterward – Reuters (free) AND Women who experience hypertensive disorders during pregnancy are at high risk for developing high blood pressure, diabetes, and high cholesterol later in life – 2 Minute Medicine (free)

Related Studies: All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease (free PDF and commentaries) AND Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease (link to abstract and free commentaries) AND Gestational Hypertension and Future Risk of Cardiovascular Disease (free research and editorial)

 


Randomized Trial: Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer

6 Jul, 2018 | 09:34h | UTC

Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Related Perspective: Metastasis-free Survival — A New End Point in Prostate Cancer Trials – New England Journal of Medicine (free)

Commentaries: Enzalutamide: Now Also for Earlier Use in Prostate Cancer? – Medscape (free registration required) AND Enzalutamide Improves Outcomes for Aggressive Prostate Cancer – MPR (free) AND Enzalutamide Postpones Metastasis for a Subset of High-Risk Patients With Prostate Cancer – Cancer Therapy Advisor (free)

 


Guideline: Fertility Preservation for Patients with Malignant Disease

6 Jul, 2018 | 09:31h | UTC

Fertility Preservation for Patients with Malignant Disease. Guideline of the DGGG, DGU and DGRM – Recommendations and Statements for Girls and Women – Geburtshilfe Frauenheilkd (free)

Related guidelines: Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Fertility preservation for patients with gynecologic malignancies: The Korean Society for Fertility Preservation clinical guidelines – Clinical and Experimental Reproductive Medicine (free) AND Fertility preservation for medical reasons in girls and women: British fertility society policy and practice guideline – Human Fertility (free)

 


Immunotherapy: Hype and Hope

6 Jul, 2018 | 09:32h | UTC

Editorial: Immunotherapy: hype and hope – The Lancet Oncology (free) (via @OphiraG)

Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)

 


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