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Daily Archives: June 12, 2018

Tue, June 12 – 10 Stories of The Day!

12 Jun, 2018 | 01:35h | UTC

 

1 – Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000–15 – The Lancet Global Health (free)

Commentaries: Pneumococcal and Haemophilus influenzae type b disease: moving numbers in the right direction – The Lancet Global Health (free) AND 1.35 million children’s lives saved by HiB and pneumococcal vaccines since 2000 – Johns Hopkins University Bloomberg School of Public Health, via MedicalXpress (free) AND Dramatic reduction in two killer childhood diseases, study finds – The Telegraph (free)

 

2 – A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: A Trial of Bezafibrate in Primary Biliary Cholangitis – NEJM Resident 360 (free) AND Bezafibrate Normalizes Liver Enzymes in PBC – MedPage Today (free registration required)

“In a randomized trial of patients with primary biliary cholangitis, bezafibrate and ursodeoxycholic acid resulted in a higher rate of complete biochemical response than ursodeoxycholic acid alone” (via @NEJM see Tweet with visual abstract)

 

3 – Viewpoint: Type 2 Myocardial Infarction—Diagnosis, Prognosis, and Treatment – JAMA (free for a limited period)

Related Review: Type 2 myocardial infarction due to supply–demand mismatch – Trends in Cardiovascular Medicine (free)

 

4 – Viewpoint: Progress in Prevention and Treatment of Acute Kidney Injury: Moving Beyond Kidney Attack – JAMA (free for a limited period)

 

5 – Erectile Dysfunction as an Independent Predictor of Future Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Circulation (free PDF)

AHA News Release: Erectile dysfunction means increased risk for heart disease, regardless of other risk factors (free)

Commentaries: Men With Erectile Dysfunction Are Twice As Likely to Have Heart Disease, Study Says – TIME (free) AND Erectile Dysfunction Linked To Higher Chances Of Heart Problems In Men – Medical Daily (free)

 

6 – pH‐neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury – The Laryngoscope (free)

Commentaries: Ingesting honey after swallowing button battery reduces injury and improves outcomes – Children’s Hospital of Philadelphia, via ScienceDaily (free) AND Honey + Sucralfate May Reduce Injury After Accidental Button Battery Ingestion – MPR (free)

 

7 – Richard Lehman’s journal review, 11 June 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 

8 – Hydroxychloroquine: An old drug with new relevance – Cleveland Clinic Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club

 

9 – New European Hypertension Guidelines Not in Harmony With US Guidance – TCTMD (free)

 

10 – A serious new hurdle for CRISPR: Edited cells might cause cancer, find two studies – STAT (free)

Related: Genome-editing tool could increase cancer risk – eCancer News (free) AND Gene editing tool may raise cancer risk in cells, scientists warn – Reuters (free) AND Expert reaction to using CRISPR/Cas9 and potential cancer risk in cells – Science Media Centre (free)

 


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