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Daily Archives: September 20, 2017

Effect of Axillary Dissection vs No Axillary Dissection on Survival in Invasive Breast Cancer and Sentinel Node Metastasis

20 Sep, 2017 | 22:31h | UTC

Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis: The ACOSOG Z0011 (Alliance) Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Author interview: Breast Cancer Surgery: Less Is More (free audio)

Commentary: In Treating Breast Cancer, Less Can Be As Good As More – American Council on Science and Health (free)

 


Systematic Review: Comprehensive geriatric assessment for older adults admitted to hospital

20 Sep, 2017 | 22:26h | UTC

Comprehensive geriatric assessment for older adults admitted to hospital – Cochrane Library (free)

Original article: Comprehensive geriatric assessment for older adults admitted to hospital – Cochrane Library (link to abstract – $ for full-text)

Related: Comprehensive assessment may reduce risk of delirium after hip fracture – NIHR Signal (free)

“Older patients are more likely to be alive and in their own homes at follow-up if they received comprehensive geriatric assessment on admission to hospital”.

 


WHO Report: The world is running out of antibiotics

20 Sep, 2017 | 22:29h | UTC

The world is running out of antibiotics, WHO report confirms – World Health Organization (free)

See WHO Reports: Antibacterial Agents in Clinical Development (free) AND Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics (free)

See also WHO Resources on Antibiotic Resistance

Commentaries: WHO report paints dire picture of antibiotic development – CIDRAP (free) AND Too few antibiotics in pipeline to tackle global drug-resistance crisis, WHO warns – The Guardian (free) AND The world is running out of antibiotics, WHO says – CNN (free text and video)

 


Guideline: Corticosteroids for sore throat

20 Sep, 2017 | 22:28h | UTC

Rapid Recommendations: Corticosteroids for sore throat: a clinical practice guideline – The BMJ (free text and infographic)

See also other Rapid Recommendations from The BMJ (all free)

 


What Does the Future Hold for Scientific Journals? Visual Abstracts and Other Tools for Communicating Research

20 Sep, 2017 | 22:30h | UTC

What Does the Future Hold for Scientific Journals? Visual Abstracts and Other Tools for Communicating Research – Clinics in Colon and Rectal Surgery (free)

 


Systematic Reviews: Improving health systems in low-income countries

20 Sep, 2017 | 22:27h | UTC

Improving health systems in low-income countries – 3 New Cochrane Library Reviews

Article 1: Implementation strategies for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Implementation strategies for health systems in low-income countries (free)

Article 2: Governance arrangements for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Effects of governance arrangements for health systems in low-income countries (free)

Article 3: Delivery arrangements for health systems in low-income countries: an overview of systematic reviews (free) AND Summary: Effects of delivery arrangements for health systems in low-income countries (free)

 


Association of spontaneous abortion with influenza vaccine

20 Sep, 2017 | 22:24h | UTC

Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010–11 and 2011–12 – Vaccine (link to abstract – $ for full-text)

Commentaries: Study signals association between flu vaccine, miscarriage – CIDRAP (free) AND New study finds link between flu vaccine and miscarriage. But is it real? – Science (free) AND Study shows miscarriage risk may have increased after flu shots, puzzling researchers – STAT (free) AND A new finding of a possible flu shot-miscarriage link shows science prioritizes vaccine safety – STAT (free)

“This study does not and cannot establish a causal relationship between repeated influenza vaccination and SAB, but further research is warranted”.

 


Meta-analysis: Low alcohol consumption and pregnancy and childhood outcomes

20 Sep, 2017 | 22:25h | UTC

Low alcohol consumption and pregnancy and childhood outcomes: time to change guidelines indicating apparently ‘safe’ levels of alcohol during pregnancy? A systematic review and meta-analyses – BMJ Open (free)

Commentaries: No change to alcohol guidelines for pregnancy – NHS Choices (free) Health risks of light drinking in pregnancy confirms that abstention is the safest approach – The Conversation (free)

 


Cohort Study: Metabolically Healthy Obese and Incident Cardiovascular Disease Events

20 Sep, 2017 | 22:23h | UTC

Metabolically Healthy Obese and Incident Cardiovascular Disease Events Among 3.5 Million Men and Women – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: New evidence shows that healthy obesity is a myth – The Conversation (free) AND Study shows so-called ‘healthy obesity’ is harmful to cardiovascular heath – Medical News Today (free) AND Obesity, even without other risk factors, leads to higher rate of cardiovascular disease – STAT (free) AND Another Study Challenges Notion of ‘Healthy Obese’ – TCTMD (free)

See related article and commentaries in our August 21st issue (see #1)

 


Guideline on the systemic treatment of psoriasis vulgaris

20 Sep, 2017 | 21:13h | UTC

European S3-Guideline on the systemic treatment of psoriasis vulgaris – Update Apremilast and Secukinumab – EDF in cooperation with EADV and IPC – European Academy of Dermatology and Venereology (free)

 


Review: Adult ADHD and comorbid disorders

20 Sep, 2017 | 21:11h | UTC

Adult ADHD and comorbid disorders: clinical implications of a dimensional approach – BMC Psychiatry (free)

 


Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease

20 Sep, 2017 | 21:12h | UTC

Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial – Annals of Internal Medicine (free)

Commentary: Cardiovascular benefits of intensive systolic blood pressure control may outweigh risks of chronic kidney disease events – 2 Minute Medicine (free)

Blood pressure measures in the SPRINT trial were done in a different way than most trials. If these results are to be incorporated in clinical practice, blood pressure measurement must be done in the same way. More details in Cardiobrief: Can SPRINT Be Used To Inform Hypertension Treatment? (free)

 


Review: Pulmonary Embolism in Children

20 Sep, 2017 | 21:09h | UTC

Pulmonary Embolism in Children – Frontiers in Pediatrics (free)

 


Review: Evaluation of bleeding in patients receiving direct oral anticoagulants

20 Sep, 2017 | 21:11h | UTC

Evaluation of bleeding in patients receiving direct oral anticoagulants – Vascular Health and Risk Management (free)

 


Review: Preventing nausea and vomiting in women undergoing regional anesthesia for cesarean section

20 Sep, 2017 | 21:10h | UTC

Preventing nausea and vomiting in women undergoing regional anesthesia for cesarean section: challenges and solutions – Local and Regional Anesthesia (free)

 


Consensus for the Management of Sinonasal Tumors

20 Sep, 2017 | 21:09h | UTC

Spanish Consensus for the Management of Sinonasal Tumors – Acta Otorrinolaringologica (free)

 


Guidelines on Upper Urinary Tract Urothelial Carcinoma

20 Sep, 2017 | 21:08h | UTC

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update – European Urology (free)

 


Should Euthanasia Be Considered Iatrogenic?

20 Sep, 2017 | 21:06h | UTC

Should Euthanasia Be Considered Iatrogenic? – AMA Journal of Ethics (free)

 


Review: Ultrasound-guided central venous catheter placement

20 Sep, 2017 | 21:07h | UTC

Ultrasound-guided central venous catheter placement: a structured review and recommendations for clinical practice – Critical Care (free)

 


Review: Multiple Myeloma Emergencies

20 Sep, 2017 | 21:06h | UTC

Multiple Myeloma Emergencies – emDocs (free)

 


Randomized Controled Trial: Efficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Chemotherapy

20 Sep, 2017 | 20:55h | UTC

Efficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase III Trial (CLOG1302 study) – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentaries: Thalidomide Improves Prevention of Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy – PracticeUpdate (free registration required) AND Adding Thalidomide to Palonosetron, Dexamethasone Reduces CINV – Oncology Nurse Advisor (free)

 


Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair

20 Sep, 2017 | 21:05h | UTC

Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair – Circulation (free)

 


Review: Diaphragm Dysfunction in Critical Illness

20 Sep, 2017 | 20:53h | UTC

Diaphragm Dysfunction in Critical Illness – Chest (free PDF)

Source: Hospital Medicine Virtual Journal Club

 


Systematic review: Non-pharmacological self-management for people living with migraine or tension-type headache

20 Sep, 2017 | 20:54h | UTC

Non-pharmacological self-management for people living with migraine or tension-type headache: a systematic review including analysis of intervention componentes – BMJ Open (free)

Commentary: Non-Pharmacological Self-Management Effective for People With Migraine or Tension-Type Headache – PracticeUpdate (free registration required)

 


FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs

20 Sep, 2017 | 20:50h | UTC

FDA Drug Safety Communication: FDA recommends separating dosing of potassium-lowering drug sodium polystyrene sulfonate (Kayexalate) from all other oral drugs (free)

Commentary: Don’t Give Kayexalate With Other Oral Drugs, FDA Warns – Medscape (free registration required)

“Patients should take orally administered prescription and over-the-counter (OTC) medicines at least 3 hours before or 3 hours after sodium polystyrene sulfonate”

 


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