Daily Archives: August 16, 2017
Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass
16 Aug, 2017 | 23:05h | UTCFive-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Off-Pump CABG Raises Long-Term Mortality Risk – Cardiobrief (free) AND Newer method of open-heart surgery carries more risks, study finds – STAT (free)
Bored reading science? Let’s change how scientists write
16 Aug, 2017 | 23:09h | UTCBored reading science? Let’s change how scientists write – The Conversation (free) (RT @Onisillos see Tweet)
“Science communicators, journalists, entrepreneurs, policymakers and interested members of the general public are all motivated to follow the latest scientific research. And yet, strangely enough, science papers are a communication tool but they are not that effective at communication”.
Benefits and safety of gabapentinoids in chronic low back pain
16 Aug, 2017 | 23:04h | UTCCommentaries: Gabapentinoids Seem to Offer Little Benefit, Substantial Risks in Low Back Pain – Physician’s First Watch (free) AND Evidence does not support the use of gabapentinoids for chronic low back pain – PLOS, via Science Daily (free) AND Gabapentinoids for Chronic Low Back Pain? Not So Fast – Practical Pain Management (free)
Pregabalin and gabapentin have significant risk of adverse effects without any demonstrated benefit in chronic low back pain.
The Fight Against Antibiotic-Resistant Bacteria Might Start With Vaccines
16 Aug, 2017 | 23:02h | UTCThe Fight Against Antibiotic-Resistant Bacteria Might Start With Vaccines – Allice Callahan, via FiveThirtyEight (free) (RT @greg_folkers see Tweet with infographic)
Fight Back Against Mosquitos
16 Aug, 2017 | 23:03h | UTCFight Back Against Mosquitos – Gates Notes (free)
Antibiotic susceptibility testing in less than 30 min
16 Aug, 2017 | 20:53h | UTCCommentaries: New ultrafast method for determining antibiotic resistance – Uppsala University, via EurekAlert (free) AND Researchers develop a rapid test for antibiotic susceptibility – CIDRAP (free)
Effect of scheduled second-look endoscopy on peptic ulcer bleeding
16 Aug, 2017 | 20:43h | UTCEffect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial – Gastrointestinal Endoscopy (link to abstract – $ for full-text)
Source: No Benefit of Second-Look Endoscopy After Endoscopic Hemostasis – Journal Watch ($)
“A single EGD with endoscopic hemostasis is not inferior to scheduled second-look endoscopy in terms of reduction in rebleeding rate of peptic ulcer bleeding. Repeat endoscopy would be helpful in the patients with unsatisfactory initial endoscopic hemostasis, use of NSAIDs, and larger amounts of transfused blood”
Immunotherapy with proinsulin peptide in human new-onset type 1 diabetes
16 Aug, 2017 | 21:00h | UTCCommentary: Immunotherapy Promising for Diabetes: Study – The Scientist (free) AND Study: Immunotherapy Halts Insulin Destruction in Type 1 Diabetes – AJMC (free) AND Immunotherapy for Type 1 Diabetes Safe, Promising in Small Study – Medscape (free registration required)
Talking therapy given by parents shows promise for childhood anxiety disorders
16 Aug, 2017 | 20:33h | UTCTalking therapy given by parents shows promise for childhood anxiety disorders – NIHR Signal (free)
Original article: Clinical outcomes and cost-effectiveness of brief guided parent-delivered cognitive behavioural therapy and solution-focused brief therapy for treatment of childhood anxiety disorders: a randomised controlled trial – The Lancet Psychiatry (free) AND Commentary: Low-intensity interventions for anxiety disorders (free)
“70% of children receiving guided parent-delivered CBT had recovered from anxiety six months after treatment” (RT @NIHR_DC see Tweet)
Should older doctors be examined, tested or forced to retire?
16 Aug, 2017 | 19:59h | UTCShould older doctors be examined, tested or forced to retire? – Reuters (free)
Original article: The Aging Physician and the Medical Profession: A Review – JAMA Surgery (link to abstract – $ for full-text)
Mitral valve prolapse and Marfan syndrome
16 Aug, 2017 | 20:12h | UTCReview: Mitral valve prolapse and Marfan syndrome – Congenital Heart Disease (free)
Role of nutrition support in adult cardiac surgery
16 Aug, 2017 | 19:48h | UTC
Sexual health concerns after cancer treatment in women
16 Aug, 2017 | 20:08h | UTCCommentary: Sexual Dysfunction in Women With Cancer: A Review of Available Interventions – Oncology Nurse Adviser (free)
The Future of Peer Review
16 Aug, 2017 | 18:09h | UTCThe Future of Peer Review – Scientific American (free)
“It’s very far from perfect, but major changes for the better are underway”
Facing Surgery Without An Anesthesiologist On Hand
16 Aug, 2017 | 18:13h | UTCGlobal Health: Imagine: Facing Surgery Without An Anesthesiologist On Hand – NPR Goats and Soda (free)
Working up high: Hospitalist practice is different at altitude
16 Aug, 2017 | 15:44h | UTCWorking up high: Hospitalist practice is different at altitude – ACP Hospitalist (free)
Related reviews: Acute high-altitude sickness – European Respiratory Review (free) AND Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment – High Altitude Medicine & Biology (free)
Pig genome editing with goal of providing organs for transplant
16 Aug, 2017 | 18:04h | UTCInactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 – Science (link to abstract – $ for full-text)
Commentaries: Birth of CRISPR’d pigs advances hopes for turning swine into organ donos – STAT (free) AND Gene editing to remove viruses brings transplant organs from pigs a step closer – The Guardian (free) AND Gene Editing Spurs Hope for Transplanting Pig Organs Into Humans – New York Times (10 articles per month are free) AND Gene editing brings pig organ transplant closer – NHS Choices (free) AND Scientists edit pig genome with goal of human organ transplants – CNN (free text and video)
Pioglitazone may increase bladder cancer risk
16 Aug, 2017 | 15:07h | UTCComparative safety of pioglitazone versus clinically meaningful treatment alternatives concerning the risk of bladder cancer in older US adults with type 2 diabetes – Diabetes, Obesity and Metabolism (link to abstract – $ for full-text)
Commentaries: Another Study Ties Pioglitazone to Bladder Cancer Risk – MedPage Today (free registration required) AND Diabetes Treatments Compared for Bladder Cancer Risk – MPR (free)
An order not to hospitalize
16 Aug, 2017 | 15:17h | UTCAn order not to hospitalize – ACP Hospitalist (free)
Original article: Are Hospital/ED Transfers Less Likely Among Nursing Home Residents With Do-Not-Hospitalize Orders? – Journal of Post-Acute and Long-Term Care Medicine (link to abstract – $ for full-text)
Epilepsy ‘Not a Rare Condition’
16 Aug, 2017 | 14:23h | UTCReport: National and State Estimates of the Numbers of Adults and Children with Active Epilepsy — United States, 2015 – CDC MMWR (free)
Commentaries: Epilepsy Isn’t As Rare As Many Might Think – And Cases Are Increasing – Forbes (free) AND Epilepsy ‘Not a Rare Condition’ – MedPage Today (free registration required)
Syphilis in the ED: Presentations, Diagnosis, and Management of the Great Imitator
16 Aug, 2017 | 15:49h | UTCSyphilis in the ED: Presentations, Diagnosis, and Management of the Great Imitator – emDocs (free)
Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours
16 Aug, 2017 | 15:03h | UTC
An Automated, Pharmacist-Driven Initiative Improves Quality of Care for Staphylococcus aureus Bacteremia
16 Aug, 2017 | 15:11h | UTCAn Automated, Pharmacist-Driven Initiative Improves Quality of Care for Staphylococcus aureus Bacteremia – Clinical Infectious Diseases (link to abstract – $ for full-text)
Commentaries: Automating antimicrobial stewardship – ACP Hospitalist (free) AND Automated intervention aids treatment of Staph aureus bacteremia – CIDRAP (free)
New, Revised Guidance Documents Cover 35 Radiology Topics
16 Aug, 2017 | 14:28h | UTCUpdated: Practice Parameters and Technical Standards – American College of Radiology (free)
News release: New, Revised Guidance Documents Cover 35 Radiology Topics – American College of Radiology, via NewsWise (free)
The American College of Radiology developed 3 new guidance documents and revised 32 others to advance the science of radiology and improve the quality of service to patients
The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy
16 Aug, 2017 | 13:31h | UTCSource: Journal Watch ($)
“we found that the risk associated with nonobstetric surgery was relatively low, confirming that surgical procedures during pregnancy are generally safe”