Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy:
3 Aug, 2017 | 19:57h | UTCEffect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Steroid treatment for type of kidney disease associated with increased risk for serious infections – The JAMA Network (free)
Renal outcomes seemed to be less frequent in the group using methylprednisolone (5,9% vs 15,9%), but the trial was stopped early due to a significantly increased risk of serious adverse events with oral methylprednisolone vs placebo (14.7% vs 3.2%, primarily excess infections)