Mon April 13 – 10 Stories of The Day!
13 Apr, 2020 | 00:31h | UTC
Commentaries: 40% of people with severe COVID-19 experience neurological complications – UPI AND AND Expert reaction to paper on neurological manifestations of patients hospitalised with COVID-19 in Wuhan, China – Science Media Centre
Commentaries: PulmCrit – Eleven reasons the NEJM paper on remdesivir reveals nothing AND Expert reaction to a study about compassionate use of remdesivir for patients with severe COVID-19 – Science Media Centre AND What Do the New Remdesivir Data Mean? – Science Translational Medicine
Related Observational Studies: Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis AND Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis
5 – D-dimer cutoffs to predict thrombosis in COVID-19 – PulmCrit
Note: this link is not an endorsement of the algorithm.
Related Guidance: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis
7 – Mechanical Ventilators Adapted from BiPAP machines?
Modified Sleep Apnea Machines May Ease the Ventilator Crunch – Wired
Mechanical ventilators based on a simple modification of CPAP and BiPAP machines – News Medical
Turning sleep apnea machines into ventilators – Berkley Engineering
See instructions and protocols developed by Mount Sinai Health System: Repurposing bi-level ventilators for use with intubated patients while minimizing risk to health care works during insufficient supply of conventional ventilation for patients with COVID-19
We want to learn more about this interesting initiative!
8 – Studies: Obesity Increases the Risk of Complications in Patients with Covid-19
2 – Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission – Clinical Infectious Diseases AND Commentary: In New York, obesity appears to raise COVID-19 risk – CIDRAP
9 – Studies: Diabetes Increases the Risk of Complications in Patients with Covid-19
1 – Prevalence and impact of diabetes among people infected with SARS-CoV-2 – Journal of Endocrinological Investigation AND Commentary: Diabetes Could Increase Severity of COVID-19, Including Risk of ICU Admission and Death – MedicalResearch.com
2 – Evidence Reviews: Diabetes and risks from COVID-19 – CEBM University of Oxford AND Managing diabetes during the COVID-19 pandemic – CEBM University of Oxford
10 – Coronavirus Disease (COVID-19) Updates / 13 April 2020 Edition
13 April 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)