Wed July 31 – 10 Stories of The Day!

1 – Cardiac arrhythmias in the emergency settings of acute coronary syndrome and revascularization: an European Heart Rhythm Association (EHRA) consensus document, endorsed by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Acute Cardiovascular Care Association (ACCA) – EP Europace (free for a limited period)

2 – New Protocol For HIV Prevention Drug Reduces The Number Of Pills Required – Kaiser Health News (free)

Related Guidelines: British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject) AND USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free guideline and commentaries)

“both organizations now endorse a strategy that requires taking just four pills timed to a specific sexual encounter — two within two to 24 hours before sex and one on each of the two following days… The new strategy, called “2-1-1” or “on-demand” PrEP, is becoming popular overseas but has gotten little traction in the United States thus far.”

3 – Acupuncture as Adjunctive Therapy for Chronic Stable Angina: A Randomized Clinical Trial – JAMA Internal Medicine (free)

Commentary: Expert reaction to study looking at acupuncture as an added treatment for angina – Science Media Centre (free)

4 – Doctors: How Job Stress Can Age Us – The New York Times (10 articles per month are free)

Related Study: Physician-Training Stress and Accelerated Cellular Aging – Biological Psychiatry (link to abstract – $ for full-text) AND Commentary: New doctors’ DNA ages six times faster than normal in first year – University of Michigan (free)

5 – Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial – The Lancet (free)

Commentaries: Placental growth factor testing for suspected pre-eclampsia – The Lancet (free) AND Placental growth factor testing can speed up diagnosis of pre-eclampsia – NIHR Signal (free)

6 – Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries: Bayesian Network Meta-analyses of Randomized Clinical Trials – JAMA Network Open (free)

7 – The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)

Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)

8 – Liberal versus restrictive red blood cell transfusion strategy in sepsis or septic shock: a systematic review and meta-analysis of randomized trials – Critical Care (free)

Related Systematic Review: Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion – Cochrane Library (free)

Related Guideline: Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients – British Committee for Standards in Haematology (free)

9 – Association between complications and death within 30 days after noncardiac surgery – Canadian Medical Association Journal (free)

Commentaries: In Noncardiac Surgery, the Post-Op Period Is Riskiest – NEJM Journal Watch (free) AND Most deaths related to noncardiac surgery occur after surgery and after discharge from hospital – Canadian Medical Association Journal (free) AND Riskiest time for surgery patients is not in the operating room – Reuters (free)

“Among adults undergoing noncardiac surgery, 99.3% of deaths occurred after the procedure and 44.9% of deaths were associated with 3 complications: major bleeding, myocardial injury and sepsis.”

10 – Infection rate among nutritional therapies for acute pancreatitis: A systematic review with network meta-analysis of randomized controlled trials – PLOS One (free)

Related Meta-Analysis: Efficacy comparisons of enteral nutrition and parenteral nutrition in patients with severe acute pancreatitis: a meta-analysis from randomized controlled trials – Bioscience Reports (free) AND Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta-analysis – Medicine (free)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)