Thu, April 4 – 10 Stories of The Day!

1 – REPORT – Medication Overload: America’s Other Drug Problem – Lown Institute (free PDF)

Executive Summary: Medication Overload: America’s Other Drug Problem – Lown Institute (free PDF)

Press Release: Growing epidemic of medication overload impacting millions of older Americans (free)

Commentaries: Medication Overload: How the drive to prescribe is harming older Americans – Lown Institute (free) AND Overprescribed: High cost isn’t America’s only drug problem – STAT (free)

Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)

2 – Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Hepatitis C-infected hearts and lungs safely transplanted – Brigham and Women’s Hospital (free) AND Hepatitis C Not A Barrier For Organ Transplantation, Study Finds – NPR (free) AND Hepatitis C-infected hearts and lungs can be safely transplanted, study says, opening way to more donors – STAT (free)

Related: Study: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries)

3 – Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet (free)

Commentaries:  Global diet and health: old questions, fresh evidence, and new horizons – The Lancet (free) AND Globally, 1 in 5 deaths are associated with poor diet – The Lancet (free) AND Bad diets killing more people globally than tobacco, study finds – The Guardian (free)

4 – Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie (free)

Related: ACG Guideline: Ulcerative Colitis in Adults (free Guidelines)

5 – European S2k Guideline on Chronic Pruritus – Acta Dermato Venerealogica (free)

6 – Treatment of Multiple Myeloma: ASCO and CCO Joint Clinical Practice Guideline (free)

7 – Preventing heart disease requires more than medicine – STAT (free)

8 – Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management – Critical Care (free)

9 – Management Options for Gastric Variceal Hemorrhage – JAMA Surgery (free for a limited period)

10 – Long-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study – Diabetes Care (free for a limited period)

Commentaries: Safe and Cheap Metformin Prevents Type 2 Diabetes Over 15 Years – Medscape (free registration required) AND Long-term metformin offsets diabetes in patients with higher glucose/HbA1c, history of gestational diabetes – MDedge (free)