Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction

True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study – The BMJ (free)

Commentaries: Evaluate Troponin Results Carefully, Researchers Warn – NEJM Journal Watch (free) AND Blood test to diagnose heart attacks is flawed, warn researchers – The BMJ (free) AND CHARIOT: 1 in 20 Hospitalized Patients Undergoing Blood Tests Have Elevated Troponin – TCTMD (free)

Related: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)

Related Commentary on Twitter

This study found that the true 99th centile of high sensitivity cardiac troponin for a general hospital population was not consistent with the manufacturer's recommended upper limit of normal #BMJResearch @NickCurzen https://t.co/IQy62VenOx

— The BMJ (@bmj_latest) March 15, 2019