Wed, March 13 – 10 Stories of The Day!

1 – Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions – European Heart Journal (free)

Commentaries: Air pollution causes 8.8 million extra early deaths a year – European Society of Cardiology (free) AND Air Pollution Causes 8.8 Million Extra Deaths a Year – U.S. News (free) AND Air pollution kills 8.8 million people per year globally, study says – UPI (free)

Related: 9 out of 10 people worldwide breathe polluted air, but more countries are taking action – World Health Organization (free) AND The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)

2 – Evidence evolving on aspirin as prevention – ACP Internist (free)

Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)

“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”

3 – Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment. – Current Pain and Headache Reports (free)

4 – Italy bans unvaccinated children from school – BBC (free)

5 – Randomized Trial of Four Treatment Approaches for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Comparison of Four Treatments for Actinic Keratosis – NEJM Resident 360 (free) AND Actinic keratosis: fluorouracil cream tops other options in randomized trial – Univadis (free registration required)

6 – Podcast: #142 Cirrhosis TIPS for Acute Complications – The Curbsiders Internal Medicine Podcast (free)

See also: Episode List

7 – Perioperative care of cannabis users: A comprehensive review of pharmacological and anesthetic considerations – Journal of Clinical Anesthesia (free)

8 – ‘Test and Treat’ reduces new HIV infections by a third in southern Africa communities – London School of Hygiene & Tropical Medicine (free)

See also: Largest ever HIV prevention study delivers sobering message – Science (free)

9 – Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Commentary: The global burden of stroke: persistent and disabling – The Lancet Neurology (free)

10 – Sensitization in Heart Transplantation: Emerging Knowledge: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Commentary: Navigating Allosensitization in Heart Transplant Candidates and Recipients – American Heart Association (free)

Top Ten Things to Know: Sensitization in Heart Transplantation: Emerging Knowledge – American Heart Association (free)