Wed, June 6 – 10 Stories of The Day!

1 – Fecal Microbiota Transplantation for Primary Clostridium difficile Infection – New England Journal of Medicine (free)

Commentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)

2 – Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Study Supports Metformin Use at eGFRs as Low as 30 – NEJM Physician’s First Watch (free) AND Metformin safe for most diabetics with kidney disease – UPI (free) AND Evidence Growing Metformin Safe in Many With Diabetes and CKD – Medscape (free registration required)

Related Studies: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease (link to abstract and commentaries) AND Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF – ACP Diabetes Monthly (free)

3 – #ASCO18 – Video (35 min): ASCO 2018 conference round up, by Dr Bishal Gyawali and Will Davies (free)

4 – #ASCO18 – Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer – New England Journal of Medicine (free)

Editorial: Endocrine Adjuvant Therapy for Localized Breast Cancer (free)

Commentary: Aromatase Inhibitor Plus Ovarian Suppression Yields Benefit in High-Risk Premenopausal Patients With Breast Cancer – The ASCO Post (free)

5 – Perspective: Beyond Legalization — Dilemmas Physicians Confront Regarding Aid in Dying – New England Journal of Medicine (free)

6 – Understanding and Improving the Health of People Who Experience Incarceration: An Overview and Synthesis – Epidemiology Reviews (free)

7 – Pulmonary Function Tests for the Generalist: A Brief Review – Mayo Clinic Proceedings (free)

8 – Catch up on new COPD guidelines – ACP Internist (free)

Original Guideline: 2018 Global Strategy for Prevention, Diagnosis and Management of COPD – Global Initiative for Chronic Obstructive Lung Disease (GOLD) (free PDF)

Pocket Guide: COPD Diagnosis, Management and Prevention (free PDF)

9 – Exercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)

Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)

10 – Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free)