Open access
COVID-19
13 May, 2021-
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[Not published yet] Observational study in Indonesia finds China’s Sinovac COVID-19 vaccine (CoronaVac) was 98% effective at preventing death and 96% effective at preventing hospitalization in healthcare workers »
Reuters -
[Preprint] Observational study finds single-dose Johnson & Johnson vaccine is 76.7% effective in preventing SARS-CoV-2 infection »
The Lancet -
Opinion | American Kids Can Wait – “The U.S. should delay shots for children until global vaccine-manufacturing capacity significantly expands and the crisis in India subsides”. »
The Atlantic -
Perspective | How covid-19 revealed the scandal of medical oxygen supplies worldwide »
Nature -
Perspective | How COVID broke the evidence pipeline »
Nature -
Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%). »
JAMA Network Open / University of Pittsburgh -
Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding. »
Applied and Environmental Microbiology -
Pfizer COVID-19 shot expanded to US children as young as 12. »
Associated Press -
M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality. »
Scientific Reports
Latest Research, Guidelines & Perspectives
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RCT: Tympanostomy-tube placement does not reduce episodes of acute otitis media among children 6 to 35 months of age with recurrent acute otitis media »
New England Journal of Medicine -
Study: More nurses lead to fewer patient deaths & readmissions, shorter hospital stays, and savings »
The Lancet -
Review: Diagnosis and treatment of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage »
Mayo Clinic Proceedings -
Systematic review: Treatments for unruptured intracranial aneurysms – There is currently insufficient good-quality evidence to support either conservative treatment or interventional treatments (microsurgical clipping or endovascular coiling) »
Cochrane Library -
2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis »
European League Against Rheumatism -
Podcast: HIV for the Pediatrician »
The Cribsiders Pediatric Medicine -
An updated review of the treatment landscape for advanced gastrointestinal stromal tumors »
Cancer -
Guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD. »
The BMJ -
Study shows BMI cut-offs for obesity and diabetes risk do not work for non-white populations. »
The Lancet Diabetes & Endocrinology -
RCT: An internet-delivered cognitive behavioral therapy (CBT) program followed by in-person CBT if necessary is noninferior to in-person CBT for the treatment of obsessive-compulsive disorder symptoms in children and adolescents. »
JAMA
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RCT: Among adults with idiopathic pulmonary fibrosis, antimicrobial therapy with co-trimoxazole or doxycycline is not associated with improved outcomes. »
JAMA -
Review: Diagnosis and management of headache. »
JAMA -
Perspective | Top five priorities for a new ICU director during the first year. »
ICU Management & Practice -
Perspective | 12 things to do to improve wellbeing in the ICU. »
ICU Management & Practice -
Perspective | The essentials for a humanized ICU. »
ICU Management & Practice -
Review: The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury. »
Canadian Journal of Anesthesiology -
Review: Neurologic assessment of the neurocritical care patient. »
Frontiers in Neurology -
M-A: Metabolic–bariatric surgery is associated with increased long-term survival in adults with obesity, the effects being more pronounced for people with pre-existing diabetes »
The Lancet -
Observational study suggests an early head‐to‐pelvis computed tomography can expedite the diagnosis of potential causes in patients with out‐of‐hospital circulatory arrest without obvious etiology »
Academic Emergency Medicine -
Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability »
JCCP Advances