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COVID-19

18 Jun, 2021

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone. »
New England Journal of Medicine
Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone. »
New England Journal of Medicine
Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19. »
New England Journal of Medicine
Dr. Fauci says the risks from the Delta variant underscore the importance of vaccines. »
NPR
Opinion | Causation or confounding: why controls are critical for characterizing long COVID – “Many of the self-reported symptoms, such as intermittent headaches or tiredness, are nonspecific and prevalent in the general population”. »
Nature
COVID-19 reinfection rate less than 1 percent for those with severe illness, study finds. »
University of Missouri-Columbia / Clinical Infectious Diseases
ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries. »
European Confederation of Medical Mycology / International Society for Human and Animal Mycology
Cohort study: swallowing and voice outcomes in patients hospitalized with COVID-19. »
Archives of Physical Medicine and Rehabilitation
RCT: Tofacitinib reduced the risk of death or respiratory failure in patients hospitalized with Covid-19 pneumonia. »
New England Journal of Medicine
[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response. »
medRxiv

Latest Research, Guidelines & Perspectives

WHO: Caesarean section rates continue to rise, amid growing inequalities in access. »
World Health Organization / BMJ Global Health
Another meta-analysis supports aspirin withdrawal one to three months after percutaneous coronary intervention and continuation with P2Y12 inhibitor monotherapy. »
The BMJ
Study commentary: a history of hypothermia for cardiac arrest, 2002-2021 (RIP). »
PulmCrit
M-A: Acute treatments for episodic migraine in adults. »
JAMA
RCT: Effects of intravenous Eptinezumab vs. placebo on headache pain and most bothersome symptom when initiated during a migraine attack. »
JAMA
Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information. »
Insights into Imaging
RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes. »
New England Journal of Medicine
Systematic review: Safety and effectiveness of metformin in patients with reduced renal function – safe and beneficial at a eGFR of 45 mL/min/1.73m2 or higher; possibly harmful at an eGFR of less than 30 mL/min/1.73m2. »
Diabetes, Obesity and Metabolism
Review: chronic pelvic pain in women. »
JAMA
The authorship rows that sour scientific collaborations. »
Nature

AHA Scientific Statement: Mechanical Complications of Acute Myocardial Infarction. »
Circulation
Review: venous and arterial thromboembolism in patients with cancer. »
JACC: CardioOncology
The BMJ Series: The future of nursing. »
The BMJ
Randomized, sham-controlled pilot study: percutaneous peripheral nerve stimulation (neuromodulation) for postoperative pain. »
Anesthesiology
RCT: A brief advice + nicotine replacement therapy sampling + active referral nearly doubled the odds of validated quitting among expectant fathers who smoked. »
JAMA Internal Medicine
Review: General health checks in adult primary care. »
JAMA
Systematic review: Endovascular thrombectomy and intra‐arterial interventions for acute ischemic stroke – “In individuals with acute ischemic stroke due to large artery occlusion in the anterior circulation, endovascular thrombectomy can increase the chance of survival with a good functional outcome”. »
Cochrane Library
M-A: Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain. »
Canadian Medical Association Journal
M-A: Among patients with kidney failure treated with dialysis, mineralocorticoid receptor antagonists reduce cardiovascular and all-cause mortality without increasing the risk of hyperkalemia. »
Clinical Journal of the American Society of Nephrology
Parental education and inequalities in child mortality: a global systematic review and meta-analysis. »
The Lancet

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Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone. »

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone. »

Audio Interview: potential treatments for children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19. »

Dr. Fauci says the risks from the Delta variant underscore the importance of vaccines. »

Opinion | Causation or confounding: why controls are critical for characterizing long COVID – “Many of the self-reported symptoms, such as intermittent headaches or tiredness, are nonspecific and prevalent in the general population”. »

COVID-19 reinfection rate less than 1 percent for those with severe illness, study finds. »

ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries. »

Cohort study: swallowing and voice outcomes in patients hospitalized with COVID-19. »

RCT: Tofacitinib reduced the risk of death or respiratory failure in patients hospitalized with Covid-19 pneumonia. »

[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response. »

WHO: Caesarean section rates continue to rise, amid growing inequalities in access. »

Another meta-analysis supports aspirin withdrawal one to three months after percutaneous coronary intervention and continuation with P2Y12 inhibitor monotherapy. »

Study commentary: a history of hypothermia for cardiac arrest, 2002-2021 (RIP). »

M-A: Acute treatments for episodic migraine in adults. »

RCT: Effects of intravenous Eptinezumab vs. placebo on headache pain and most bothersome symptom when initiated during a migraine attack. »

Differential diagnosis of uncommon prostate diseases: combining mpMRI and clinical information. »

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes. »

Systematic review: Safety and effectiveness of metformin in patients with reduced renal function – safe and beneficial at a eGFR of 45 mL/min/1.73m2 or higher; possibly harmful at an eGFR of less than 30 mL/min/1.73m2. »

Review: chronic pelvic pain in women. »

The authorship rows that sour scientific collaborations. »

AHA Scientific Statement: Mechanical Complications of Acute Myocardial Infarction. »

Review: venous and arterial thromboembolism in patients with cancer. »

The BMJ Series: The future of nursing. »

Randomized, sham-controlled pilot study: percutaneous peripheral nerve stimulation (neuromodulation) for postoperative pain. »

RCT: A brief advice + nicotine replacement therapy sampling + active referral nearly doubled the odds of validated quitting among expectant fathers who smoked. »

Review: General health checks in adult primary care. »

M-A: Ibuprofen and other NSAIDs superior to codeine for managing outpatient postoperative pain. »

M-A: Among patients with kidney failure treated with dialysis, mineralocorticoid receptor antagonists reduce cardiovascular and all-cause mortality without increasing the risk of hyperkalemia. »

Parental education and inequalities in child mortality: a global systematic review and meta-analysis. »

Specialties

Join LinksMedicus’ Telegram Channels to receive updates in your specialty.

Stay Updated in Your Specialty