Open access
COVID-19
19 Oct, 2021-
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Systematic Review: Colchicine for the treatment of COVID‐19 – not beneficial for hospitalized patients; inconclusive evidence for the treatment of non-hospitalized patients, “probably slightly reduces the need for hospitalization or death within 28 days compared to placebo”. »
Cochrane Library -
Long-term consequences of the misuse of ivermectin data. »
The Lancet Infectious Diseases -
Editorial: Preparing for “Disease X”. »
Science -
China’s COVID vaccines have been crucial — now immunity is waning. »
Nature -
BJS commission on surgery and perioperative care post-COVID-19. »
British Journal of Surgery -
RCT supports the use of therapeutic heparin in moderately ill patients admitted to the hospital with Covid-19. »
The BMJ -
J&J COVID-19 Vaccine: FDA recommends booster shot for all adults aged 18 and older at least two months following initial vaccination with the single-shot vaccine. »
Johnson & Johnson -
Review: SARS-CoV-2 Dose, Infection, and Disease Outcomes for COVID-19. »
Clinical Infectious Diseases -
[Preprint] Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – “Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%”. »
medRxiv
Latest Research, Guidelines & Perspectives
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Review: Athletes and Hypertension. »
Current Cardiology Reports -
Cohort study: Acute urinary retention may be a clinical marker of occult prostate cancer and other urogenital, colorectal, and neurological cancers. »
The BMJ -
Systematic Review: Restricting access to poisons is associated with decreases in suicide by poisoning without an equivalent shift toward other methods. »
JAMA Network Open -
Guideline: Management of anticoagulants and antiplatelet agents in cutaneous surgery. »
German Society of Dermatology -
Another observational study suggests Rivaroxaban is associated with higher rates of gastrointestinal bleeding than other direct oral anticoagulants. »
Annals of Internal Medicine -
Cluster RCT: An exercise intervention may improve academic achievement among children. »
Pediatrics -
Systematic Review: Calcium channel blockers versus other classes of drugs for hypertension – “there is moderate certainty evidence that diuretics reduce major cardiovascular events and congestive heart failure more than CCBs”. »
Cochrane Library -
Podcast: Diagnosis and treatment of Celiac Disease. »
The Curbsiders -
Urolithiasis: ED presentations, evaluation, management, and disposition. »
emDocs -
Preoperative hypertension: perioperative implications and management. »
BJA Education
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Bioethics | The Reluctant Patient and the Insistent Doctor. »
The American Journal of Medicine -
Opinion | Multi-cancer screening tests: communicating about risks should be prioritized. »
The American Journal of Medicine -
M-A: Risk factors for invasive candida infection in critically ill patients – The risk factors associated with the highest risk for ICI were broad spectrum antibiotics (OR 5.6), blood transfusion (OR 4.9), Candida colonization (OR 4.7), central venous catheter (OR 4.7) and total parenteral nutrition (OR 4.6). »
Chest -
Review: Stroke prevention after cryptogenic stroke. »
Current Cardiology Reports -
Review: Wilms Tumor. »
Nature Reviews Disease Primers -
Management of Diabetes Mellitus in patients with CKD: Core Curriculum 2022. »
American Journal of Kidney Diseases -
Guidelines for anesthesiologists on patient blood management in cardiac surgery. »
Society of Thoracic Surgeons -
Guidelines for the surgical management of ulcerative colitis. »
American Society of Colon and Rectal Surgeons -
Viewpoint: Surgical overtreatment and shared decision-making—the limits of choice. – “Payment models further incentivize surgical intervention. Fee-for-service payment plans reward surgeons for operating, not for ensuring that surgery is right for a patient”. »
JAMA Surgery -
RCT: After third molar surgery, Ibuprofen doses above 400 mg did not significantly increase the analgesic effect, and Paracetamol 1000/codeine 60 mg was not more effective than ibuprofen 400 mg. »
European Journal of Clinical Pharmacology