Open access
COVID-19
15 Jan, 2021-
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Observational study: Among patients hospitalized with Covid-19 not receiving mechanical ventilation, transfusion of plasma with higher anti–SARS-CoV-2 IgG antibody levels is linked to lower risk of death than transfusion of plasma with lower antibody levels »
New England Journal of Medicine -
Opinion: RCTs don’t justify using convalescent plasma or antibody cocktails »
PulmCrit -
Progression of myopia in school-aged children after COVID-19 home confinement »
JAMA Ophthalmology -
NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19” »
National Institutes of Health -
Perspective: Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux? »
HIV and ID Observations -
Covid-19 Vaccine — Frequently Asked Questions »
New England Journal of Medicine -
Covid-19: When to start invasive ventilation is “the million dollar question” »
The BMJ -
COVID-19 measures also suppress flu—for now »
Science -
Covid-19 deaths are the highest they’ve ever been — and the more infectious variants could make things much worse »
STAT
Latest Research, Guidelines & Perspectives
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Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences »
The BMJ -
Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes »
The BMJ -
Cohort study: Even small amounts of alcohol consumption linked to increased risk of atrial fibrillation »
European Heart Journal -
Randomized trial: Naltrexone-Bupropion combination may help some people (13.6% vs. 2.5% with placebo) with methamphetamine use disorder »
New England Journal of Medicine -
Study: Pulmonary embolism detected in 6% of patients with COPD admitted to the hospital with acute worsening of respiratory symptoms »
JAMA -
Clinical trial finds vitamin D does not ward off colds and flu »
The Lancet Diabetes & Endocrinology -
Dietary Guidelines for Americans, 2020-2025 »
United States Department of Agriculture -
A new mandate highlights costs, benefits of making all scientific articles free to read »
Science -
Study: Seizure frequency does not increase during Pregnancy »
New England Journal of Medicine -
Consequences to patients, clinicians, and manufacturers when very serious adverse drug reactions are identified (1997–2019) »
EClinicalMedicine
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Cohort study: Piperacillin/tazobactam linked to increased risk of acute kidney injury when compared to cefepime or meropenem »
Clinical Infectious Diseases -
Randomized trial: Surgical and drug treatment options lead to similar outcomes for diabetic eye disease »
JAMA -
[Abstract Only] A randomized clinical trial of low dose warfarin therapy for improving the longevity of permanent arteriovenous catheters »
Annals of Vascular Surgery -
Randomized trial: Biological mesh results in significantly more complications compared to synthetic mesh in noncomplex ventral hernia repair »
Annals of Surgery -
Randomized trial: Cannula with long and narrow tubing noninferior to short binasal prongs for noninvasive ventilation in preterm infants »
JAMA Pediatrics -
CSCO and ASCO Guideline: Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma »
American Society of Clinical Oncology -
Randomized trial: Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma »
The Lancet -
Systematic review: Prostatic arterial embolization for men with symptomatic benign prostatic hyperplasia provides similar short term (up to 12 months) improvement in urologic symptom scores and quality of life, but with an increase in re-treatment rates »
Cochrane Library -
Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer »
Cochrane Library -
Systematic review: Oral hygiene care with chlorhexidine mouthwash or gel in critically ill patients probably reduces the incidence of developing ventilator-associated pneumonia »
Cochrane Library