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Covid-19 (Public Health Issues)

Editorial: Covid-19 has redefined airborne transmission

16 Apr, 2021 | 06:26h | UTC

Covid-19 has redefined airborne transmission – The BMJ

Commentaries: Future attempts to reduce Covid-19 spread should focus on tackling airborne transmission – News Medical AND Open the windows to curb COVID spread: experts – MedicalXpress

Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more) AND Deep Cleaning Isn’t a Victimless Crime – The Atlantic

 


Were pregnant women more affected by COVID-19 in the second wave of the pandemic?

16 Apr, 2021 | 06:24h | UTC

Were pregnant women more affected by COVID-19 in the second wave of the pandemic? – The Lancet

Related: Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

 


Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – “we estimate that P.1 may be 1.7–2.4-fold more transmissible”

15 Apr, 2021 | 07:09h | UTC

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science

Commentary: The P.1 coronavirus variant is twice as transmissible as earlier strains – ScienceNews

 


Vaccines alone will not stop Covid spreading – here’s why (visual guide to the “Swiss cheese model”)

15 Apr, 2021 | 06:53h | UTC

Vaccines alone will not stop Covid spreading – here’s why – BBC

 


Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient

15 Apr, 2021 | 06:51h | UTC

Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient – JAMA

Related studies: Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates AND Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine

 


Spatiotemporal pattern of COVID-19 spread in Brazil

15 Apr, 2021 | 07:06h | UTC

Spatiotemporal pattern of COVID-19 spread in Brazil – Science

 

Commentary on Twitter

 


Case Report: Thrombotic Thrombocytopenia after Johnson & Johnson Vaccine

15 Apr, 2021 | 07:02h | UTC

Thrombotic Thrombocytopenia after Ad26.COV2.S Vaccination – New England Journal of Medicine

Related: U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots AND 4 Things to Know About the J&J Covid Vaccine Pause – Kaiser Health News AND Why Johnson & Johnson shots were paused — and why that’s so confusing – Vox AND Is it the adenovirus vaccine technology, used by AstraZeneca and Johnson & Johnson, causing blood clots? There’s no evidence yet – The Conversation

 


Opinion | Deep Cleaning Isn’t a Victimless Crime

15 Apr, 2021 | 06:56h | UTC

Deep Cleaning Isn’t a Victimless Crime – The Atlantic

Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more)

 


Guidance: Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes

15 Apr, 2021 | 06:54h | UTC

Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes – Public Health Agency of Canada

 

Commentary on Twitter

 


Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients

15 Apr, 2021 | 06:49h | UTC

Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients – British Journal of Sports Medicine

Commentaries: Exercise may strongly protect against poor COVID-19 outcomes – CIDRAP AND One Good Way to Help Beat COVID: Exercise – HealthDay

 


Observational study: Impact of the influenza vaccine on COVID-19 infection rates and severity

15 Apr, 2021 | 06:47h | UTC

Impact of the influenza vaccine on COVID-19 infection rates and severity – American Journal of Infection Control

Commentary: Flu shot associated with fewer, less severe COVID cases – University of Michigan

 


New studies suggest SARS-CoV-2 variant B.1.1.7 is not more deadly, just more transmissible

14 Apr, 2021 | 02:12h | UTC

Study 1: Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study – The Lancet Public Health

Study 2: Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study – The Lancet Infectious Diseases

Commentaries: Expert reaction to two papers looking at the transmissibility and severity of the B.1.1.7 variant – Science Media Centre AND UK coronavirus variant not more deadly, just spreads more easily, studies find – LiveScience

 


U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots

14 Apr, 2021 | 02:16h | UTC

Joint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine – U.S. Food & Drug Administration

Commentaries: Covid-19: US suspends Johnson and Johnson vaccine rollout over blood clots – BMJ AND CDC and FDA recommend US pause use of Johnson & Johnson’s Covid-19 vaccine over blood clot concerns – CNN AND US halts J&J COVID vaccine after reports of blood clots – CIDRAP AND U.S. urges pause on use of Johnson & Johnson Covid-19 vaccine after rare blood clotting cases – CIDRAP

 


WHO, agencies urge countries to suspend sale of live wild mammals at markets

14 Apr, 2021 | 02:06h | UTC

WHO, agencies urge countries to suspend sale of live wild mammals at markets – Reuters

Original Guidance: Reducing public health risks associated with the sale of live wild animals of mammalian species in traditional food markets – World Health Organization

 


Opinion | Coronavirus Variants Don’t Have to Be Scary. Still, Mask Up.

14 Apr, 2021 | 02:05h | UTC

Coronavirus Variants Don’t Have to Be Scary. Still, Mask Up. – The New York Times

 

Commentary on Twitter

 


Review: Vaccine development for emerging infectious diseases

14 Apr, 2021 | 02:01h | UTC

Vaccine development for emerging infectious diseases – Nature

 


Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19

14 Apr, 2021 | 01:59h | UTC

Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19 – JAMA Network Open

Commentary: CDC: 1 in 3 children hospitalized with COVID-19 requires treatment in ICU – UPI AND 12% of Children with COVID Are Hospitalized: Study – WebMD

 

Commentary on Twitter

 


RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19

13 Apr, 2021 | 05:30h | UTC

Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19 – PRINCIPLE / University of Oxford

Original study (preprint): Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial – medRxiv

Commentary: Covid: Asthma drug ‘speeds up recovery at home’ – BBC

Related study: Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19 (study and commentaries)

 


Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults

13 Apr, 2021 | 05:27h | UTC

Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults – Canadian Medical Association Journal

Commentary: Children may be less infectious in spreading SARS-CoV-2 to others – News Medical

 


[Press release – not published yet] Phase 3 prevention trial showed 81% reduced risk of symptomatic SARS-CoV-2 infections with subcutaneous administration of monoclonal antibodies

13 Apr, 2021 | 05:26h | UTC

Phase 3 prevention trial showed 81% reduced risk of symptomatic SARS-CoV-2 infections with subcutaneous administration of REGEN-COV™ (Casirivimab with Imdevimab) – Regeneron

Commentaries: Regeneron says antibody cocktail prevented Covid when given as simple injection, not an IV – STAT AND Regeneron’s Covid mAb as a prophylactic injection: Reduced risk of symptomatic infection by 81% – Endpoint News

 


China considers mixing COVID-19 vaccines to boost protection rate

13 Apr, 2021 | 05:24h | UTC

China considers mixing COVID-19 vaccines to boost protection rate – Reuters

 


Perspective | They Tested Negative for Covid. Still, They Have Long Covid Symptoms.

13 Apr, 2021 | 05:23h | UTC

They Tested Negative for Covid. Still, They Have Long Covid Symptoms. – Kaiser Health News

 

Commentary on Twitter

 


Cohort study: SARS-CoV-2 infection rates of antibody-positive vs. antibody-negative health-care workers – previous infection was associated with 84% lower risk of (re)infection

12 Apr, 2021 | 01:30h | UTC

SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN) – The Lancet

Commentary: Correlates of protection from SARS-CoV-2 infection – The Lancet

 

Commentary on Twitter

 


[Preprint] Pfizer vaccine less effective for SARS-CoV-2 variant B.1.351

12 Apr, 2021 | 01:26h | UTC

Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals – medRxiv

Commentaries: South African variant may evade protection from Pfizer vaccine, Israeli study says – Reuters AND Israeli data shows South African variant able to ‘break through’ Pfizer vaccine – The Times of Israel

Related: Another study indicates SARS-CoV-2 variant B.1.351, but not variant B.1.1.7, has partial resistance to neutralizing antibodies generated by natural infection or mRNA vaccination AND SARS-CoV-2 variants B.1.351 and P.1 can escape from therapeutic antibodies and evade antibodies induced by infection or mRNA vaccination AND B.1.351 strain of SARS-CoV-2 neutralization titer reduced 8- to 9-fold for Pfizer and AstraZeneca vaccinees. Convalescent plasma and therapeutic antibodies were less effective against this variant as well.

 


[Preprint] Efficacy and safety of CoronaVac in healthcare professionals in Brazil

12 Apr, 2021 | 01:17h | UTC

Efficacy and Safety of a COVID-19 Inactivated Vaccine in Healthcare Professionals in Brazil: The PROFISCOV Study – SSRN

 

Commentary on Twitter (thread – click for more)

 


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