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Covid-19 (Public Health Issues)

One third of patients hospitalized with COVID-19 have lung changes after a year

7 May, 2021 | 08:37h | UTC

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study – The Lancet Respiratory Medicine

Commentaries: One third of patients hospitalized with COVID-19 have lung changes after a year – University of Southampton AND An integrated understanding of long-term sequelae after acute COVID-19 – The Lancet Respiratory Medicine

 

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

7 May, 2021 | 08:35h | UTC

News release: COVID-19 has caused 6.9 million deaths globally, more than double what official reports show – Institute for Health Metrics and Evaluation

Report: Estimation of total mortality due to COVID-19 – Institute for Health Metrics and Evaluation

Commentaries: New analysis finds global Covid death toll is double official estimates – STAT AND Global COVID-19 death toll more than double official estimates – IHME – Reuters

 

Cohort study: Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S. 11 excess venous thromboembolic events per 100 000 vaccinations; 2.5 excess cerebral venous thrombosis per 100 000 vaccinations.

7 May, 2021 | 08:33h | UTC

Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study – The BMJ

Editorial: Thromboembolism and the Oxford-AstraZeneca vaccine – The BMJ

Commentaries: Thrombosis and bleeding after the Oxford-AstraZeneca covid-19 vaccination – The BMJ Opinion AND Putting risks into context: covid-19 vaccines and blood clots – The BMJ Opinion AND Expert reaction to study from Denmark and Norway looking at rare blood clots after the Oxford-AstraZeneca vaccine – Science Media Centre

 

Commentary on Twitter

 

Opinion | Covid-19: Sputnik vaccine rockets, thanks to Lancet boost

7 May, 2021 | 08:31h | UTC

Covid-19: Sputnik vaccine rockets, thanks to Lancet boost – The BMJ

 

Commentary on Twitter

 

In shock move, US backs waiving patents on COVID vaccines. “The development from the Biden administration draws cheers from public health researchers and ire from drugmakers.”

6 May, 2021 | 09:10h | UTC

In shock move, US backs waiving patents on COVID vaccines – Nature

See also: U.S. will back proposal to waive intellectual property rights and boost Covid-19 vaccine production – STAT AND Statement from the Executive Director of UNAIDS, Winnie Byanyima on the decision by the United States of America to support the TRIPS waiver for COVID-19 vaccines – UNAIDS AND WHO Director-General commends United States decision to support temporary waiver on intellectual property rights for COVID-19 vaccines – World Health Organization

 

Commentary on Twitter

 

RCT: Novavax vaccine is 49.4% effective against B.1.351 SARS-CoV-2 variant.

6 May, 2021 | 09:08h | UTC

Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant – New England Journal of Medicine

 

Observational study in Qatar: Pfizer–BioNTech Covid vaccine is 89.5% effective against B.1.1.7 variant and 75.0% effective against B.1.351 variant. Vaccine effectiveness against severe, critical, or fatal disease with any SARS-CoV-2 variant was very high, at 97.4%.

6 May, 2021 | 09:06h | UTC

Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants – New England Journal of Medicine

Commentary: Pfizer-BioNTech vaccine offers strong protection against key variants of concern, real-world data from Qatar shows – The Washington Post

 

Commentary on Twitter

 

Observational study in Israel: Pfizer-BioNTech is 95.3% effective against SARS-CoV-2 infection.

6 May, 2021 | 09:04h | UTC

Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data – The Lancet

Commentaries: Expert reaction to Israel nation-wide study looking at Pfizer vaccine effectiveness – Science Media Centre AND Covid-19: Two doses of Pfizer vaccine are “highly effective” against infection, hospital admission, and death, study finds – The BMJ

 

Perspective | How many COVID deaths are acceptable in a post-pandemic world? “Even after mass vaccinations, some hospitalizations and deaths from the coronavirus are inevitable — but opinions differ on how many is too many for a return to relative normality.”

6 May, 2021 | 08:59h | UTC

How many COVID deaths are acceptable in a post-pandemic world? – Nature

 

[Press release – not published yet] Moderna announces positive initial booster data against SARS-CoV-2 variants of concern.

6 May, 2021 | 08:57h | UTC

Moderna Announces Positive Initial Booster Data Against SARS-CoV-2 Variants of Concern – Moderna

Commentary: We just got our first evidence that Moderna’s coronavirus booster shot works to fight variants – Insider

 

Commentaries on Twitter

 

COVID has pushed medical research into remote trials, benefiting patients and scientists

5 May, 2021 | 08:38h | UTC

COVID Has Pushed Medical Research into Remote Trials, Benefiting Patients and Scientists – Scientific American

 

What’s the future of vaccines linked to rare clotting disorders? Science breaks down the latest

5 May, 2021 | 08:37h | UTC

What’s the future of vaccines linked to rare clotting disorders? Science breaks down the latest – Science

 

Covax: How will Covid vaccines be shared around the world?

5 May, 2021 | 08:35h | UTC

Covax: How will Covid vaccines be shared around the world? – BBC

Related: WHO chief – The world can bring the global COVID-19 pandemic under control in the coming months provided it distributes the necessary resources fairly AND A year in the COVID-19 vaccine scheme COVAX

 

Perspective | We may never achieve long-term global herd immunity for COVID. But if we’re all vaccinated, we’ll be safe from the worst

5 May, 2021 | 08:33h | UTC

We may never achieve long-term global herd immunity for COVID. But if we’re all vaccinated, we’ll be safe from the worst – The Conversation

See also: Reaching ‘Herd Immunity’ Is Unlikely in the U.S., Experts Now Believe – The New York Times (free registration required) AND We May Never Get to Herd Immunity – Think Global Health

 

China’s COVID vaccines are going global — but questions remain

5 May, 2021 | 08:32h | UTC

China’s COVID vaccines are going global — but questions remain – Nature

 

Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose

4 May, 2021 | 08:51h | UTC

Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose – Imperial College London

Original study: Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose – Science

 

Commentary on Twitter (thread – click for more)

 

WHO lists Moderna vaccine for emergency use

4 May, 2021 | 08:49h | UTC

WHO lists Moderna vaccine for emergency use – World Health Organization

 

WHO Inches Closer to Approval of Chinese Sinopharm and Sinovac Vaccines

4 May, 2021 | 08:49h | UTC

WHO Inches Closer to Approval of Chinese Sinopharm and Sinovac Vaccines – Health Policy Watch

 

COVID studies note online learning stress, fewer cases in schools with protocols

4 May, 2021 | 08:47h | UTC

COVID studies note online learning stress, fewer cases in schools with protocols – CIDRAP

Study 1: COVID-19 Infections Among Students and Staff in New York City Public Schools – Pediatrics

Study 2:  Household COVID-19 risk and in-person schooling – Science

Study 3: Caregiver Perceptions of Children’s Psychological Well-being During the COVID-19 Pandemic – JAMA Network Open AND Editorial: It Is Time to End the Debate Over School Reopening

 

Novel coronavirus really is seasonal, study suggests

4 May, 2021 | 08:46h | UTC

Novel coronavirus really is seasonal, study suggests – LiveScience

Original study: Climate and the spread of COVID-19 – Scientific Reports

 

[Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – up to one-third of COVID-19 patients analyzed in this review, 89% of whom were hospitalized, experienced at least one neurological manifestation

4 May, 2021 | 08:44h | UTC

Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – medRxiv

Commentary: Study finds one-third of COVID-19 patients experience neurological symptoms – News Medical

 

[Preprint] Preventing disproportionate mortality in ICU overload situations: Empirical evidence from the first COVID-19 wave in Europe – “transferring patients proactively out of developing hotspots to less affected regions, well before high ICU workload situations emerge, will improve patient outcomes”

4 May, 2021 | 08:42h | UTC

Preventing disproportionate mortality in ICU overload situations: Empirical evidence from the first COVID-19 wave in Europe – medRxiv

 

Case series of 12 patients with cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccination – all women younger than 60 years, with symptoms from 6 to 15 days after vaccination

3 May, 2021 | 05:43h | UTC

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021 – JAMA

Editorial: Assessing a Rare and Serious Adverse Event Following Administration of the Ad26.COV2.S Vaccine – JAMA

See also: Safety Monitoring of the Janssen (Johnson & Johnson) COVID-19 Vaccine — United States, March–April 2021 – Centers for Disease Control and Prevention AND Updated Recommendations from the Advisory Committee on Immunization Practices for Use of the Janssen (Johnson & Johnson) COVID-19 Vaccine After Reports of Thrombosis with Thrombocytopenia Syndrome Among Vaccine Recipients — United States, April 2021 – Centers for Disease Control and Prevention

Related: AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.”

 

Report: The Epidemics that Didn’t Happen – The lessons that can be learned from epidemics that were contained

3 May, 2021 | 05:41h | UTC

The Epidemics that Didn’t Happen – Prevent Epidemics

Commentaries: ‘The next big one must be prevented’: The lessons the world can learn from epidemics that were contained – STAT AND Former CDC director: We can prevent the next pandemic – CNN AND Learning from the “Near Misses” – Global Health NOW

 

Analysis: Why is India having a covid-19 surge?

3 May, 2021 | 05:39h | UTC

Why is India having a covid-19 surge? – The BMJ

See also: India Is Counting Thousands Of Daily COVID Deaths. How Many Is It Missing? – NPR AND Opinion: India’s covid-19 crisis is a dire warning for all countries – The Washington Post AND India’s nightmare: Record high cases, vaccine shortages, hospital fires. – The New York Times AND India coronavirus: New record deaths as virus engulfs India – BBC

 

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