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Bioethics

Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models

2 Jul, 2020 | 08:49h | UTC

Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models – New England Journal of Medicine

Related: Challenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development? – JAMA AND Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development (commentaries on the subject) AND Feasibility, potential value and limitations of establishing a closely monitored challenge model of experimental COVID-19 infection and illness in healthy young adult volunteers – World Health Organization (draft document for public comments) AND Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure – The Journal of Infectious Diseases AND Ethics of controlled human infection to address COVID-19 – Science AND Extraordinary diseases require extraordinary solutions – Vaccine

 


Opinion: The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19

2 Jul, 2020 | 08:46h | UTC

The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19 – Annals of Internal Medicine

Related: Excluding pregnancy from COVID-19 trials: Protection from harm or the harm of protection? – Canadian Medical Association Journal

 


The Ethics of COVID-19 Treatment Studies: Too Many are Open, Too Few are Double-masked

2 Jul, 2020 | 08:43h | UTC

The ethics of COVID-19 treatment studies: too many are open, too few are double-masked – CEBM Oxford

 


The Line is Forming for a COVID-19 Vaccine. Who Should be at the Front?

1 Jul, 2020 | 07:49h | UTC

The line is forming for a COVID-19 vaccine. Who should be at the front? – Science

 


Editorial: Commercial Influence and Covid-19

25 Jun, 2020 | 08:18h | UTC

Commercial influence and covid-19 – The BMJ

 


Review: Ethics for Surgeons During the COVID-19 Pandemic

23 Jun, 2020 | 08:31h | UTC

Ethics for surgeons during the COVID-19 pandemic, review article – Annals of Medicine and Surgery

 


Ethical Dilemmas Due to the Covid-19 Pandemic

19 Jun, 2020 | 09:33h | UTC

Ethical dilemmas due to the Covid-19 pandemic – Annals of Intensive Care

 


Research: Vaccination as a Social Contract

17 Jun, 2020 | 02:25h | UTC

Vaccination as a social contract – Proceedings of the National Academy of Sciences

 


Opinion: John Ioannidis and Medical Tribalism in the Era of Covid-19

12 Jun, 2020 | 09:21h | UTC

Opinion: John Ioannidis and Medical Tribalism in the Era of Covid-19 – Undark

“The critical questions the Stanford professor is raising about Covid-19 have gotten lost amid partisan bickering”

 

 


Debate: What to Think of Public Health Experts Defending Protests During the Pandemic?

12 Jun, 2020 | 09:19h | UTC

Opinion 1: Public-Health Experts Are Not Hypocrites – The Atlantic

Opinion 2: We often accuse the right of distorting science. But the left changed the coronavirus narrative overnight – The Guardian

“Health is about more than simply remaining free of coronavirus infection.” (from The Atlantic)

“Progressives blithely accepted throwing millions out of work to fight coronavirus – but now urge street protests to fight racism” (from The Guardian)

 


Reporting of Financial Conflicts of Interest by Canadian Clinical Practice Guideline Producers

11 Jun, 2020 | 09:22h | UTC

Reporting of financial conflicts of interest by Canadian clinical practice guideline producers: a descriptive study – Canadian Medical Association Journal

 


Lancet, New England Journal Retract Covid-19 Studies, Including one That Raised Safety Concerns About Malaria Drugs

5 Jun, 2020 | 05:07h | UTC

STAT: Lancet, New England Journal retract Covid-19 studies, including one that raised safety concerns about malaria drugs

Science: Two elite medical journals retract coronavirus papers over data integrity questions

NEJM: Retraction: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. N Engl J Med. DOI: 10.1056/NEJMoa2007621.

The Lancet: Retraction: “Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis”

 


Challenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development?

5 Jun, 2020 | 05:01h | UTC

Challenge Trials—Could Deliberate Coronavirus Exposure Hasten Vaccine Development? – JAMA

Related: Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development (other commentaries on the subject)

 


Debate: Should Governments Continue Lockdown to Slow the Spread of Covid-19? (Yes—Edward R Melnick vs. No—John PA Ioannidis)

4 Jun, 2020 | 05:05h | UTC

Head to Head: Should governments continue lockdown to slow the spread of covid-19? – The BMJ

 


Perspective: For Seniors, COVID-19 Sets Off A Pandemic Of Despair

29 May, 2020 | 03:23h | UTC

For Seniors, COVID-19 Sets Off A Pandemic Of Despair – Kaiser Health News

 


Opinion: Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 to Speed Vaccine Development

29 May, 2020 | 03:19h | UTC

Ethical guidelines for deliberately infecting volunteers with COVID-19 – Journal of Medical Ethics

Commentary: COVID-19 vaccine development: New guidelines for ethical approach to infecting trial volunteers – University of Warwick

Related: Challenge trials can speed development of a Covid-19 vaccine. Planning for them needs to start now – STAT AND AstraZeneca says it may consider exposing vaccine trial participants to virus – Reuters

 


Ethical Guidelines for COVID-19 Tracing Apps

29 May, 2020 | 03:18h | UTC

Ethical guidelines for COVID-19 tracing apps – Nature

 


Study: Financial Ties Between Leaders of Influential US Professional Medical Associations and Industry

28 May, 2020 | 09:37h | UTC

Financial ties between leaders of influential US professional medical associations and industry: cross sectional study – The BMJ

Editorial: Financial relations between leaders of US medical societies and industry – The BMJ

 


Opinion: The ‘Just Stay Home’ Message Will Backfire

26 May, 2020 | 09:33h | UTC

The ‘Just Stay Home’ Message Will Backfire – The Atlantic

“We need less extreme and more nuanced recommendations for navigating life during the pandemic.”

 

Related Commentary on Twitter

 


Ethics of Controlled Human Infection to Address COVID-19

22 May, 2020 | 04:49h | UTC

Ethics of controlled human infection to address COVID-19 – Science

 


Allocating Scarce Resources and Triaging Patients during the COVID-19 Pandemic

13 May, 2020 | 01:55h | UTC

Allocating Scarce Resources and Triaging Patients during the COVID-19 Pandemic – Journal of the American College of Cardiology

Commentary: COVID-19 Triage, Allocation Decisions Must Be Guided by Ethical Principles and Values – American College of Cardiology

 


Ethics and Governance for Digital Disease Surveillance

12 May, 2020 | 03:23h | UTC

Ethics and governance for digital disease surveillance – Science

 


AGS Position Statement: Resource Allocation Strategies and Age‐Related Considerations in the COVID‐19 Era

7 May, 2020 | 09:24h | UTC

AGS Position Statement: Resource Allocation Strategies and Age‐Related Considerations in the COVID‐19 Era and Beyond – Journal of the American Geriatrics Society

News Release: Position statement addresses difficult issue: allocating scare resources in COVID-19 era – American Geriatrics Society

“Age should never be used as a means for categorically excluding someone from what is ordinarily the standard of care, nor should age “cut-offs” be used in allocation strategies.”

 


Privileges and Immunity Certification During the COVID-19 Pandemic

7 May, 2020 | 09:13h | UTC

Privileges and Immunity Certification During the COVID-19 Pandemic – JAMA

Related article: The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”) – JAMA

See also: Ethical and Legal Challenges of COVID-19 Immunity Certificates (articles and commentaries on the subject)

 


Ethical and Legal Challenges of COVID-19 Immunity Certificates

5 May, 2020 | 04:16h | UTC

COVID-19 immunity passports and vaccination certificates: scientific, equitable, and legal challenges – The Lancet

Related: Covid-19 ‘immunity certificates’: practical and ethical conundrums – STAT AND The Dangerous History of Immunoprivilege – The New York Times AND “COVID-19 ‘Immunity Passports’ and Dystopian Segregation: A Few Concerns” – Bioethics.net

 


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