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Daily Archives: December 1, 2022

WHO Pocket book of primary health care for children and adolescents.

1 Dec, 2022 | 14:09h | UTC

Pocket book of primary health care for children and adolescents: guidelines for health promotion, disease prevention and management from the newborn period to adolescence (2022) – World Health Organization

 


M-A | Sodium restriction in patients with heart failure.

1 Dec, 2022 | 14:08h | UTC

Sodium Restriction in Patients With Heart Failure: A Systematic Review and Meta-Analysis of Randomized Clinical Trials – Circulation: Heart Failure (link to abstract – $ for full-text)

Commentary: Sodium Restriction No Help, No Harm in HF, Meta-analysis Confirms – TCTMD

 

Commentary on Twitter

 


Phase 2b RCT | Cannabidiol oil failed to relieve symptoms in advanced cancer.

1 Dec, 2022 | 14:04h | UTC

Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD) – Journal of Clinical Oncology

Commentary: Cannabis oil failed to improve pain or quality of life in palliative care cancer patients, study shows – The Guardian

Related:

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Systematic Review: Cannabis-based products for chronic pain.

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults. 

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife. 

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero. 

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 


RCT | Combining loop with thiazide diuretics for decompensated heart failure.

1 Dec, 2022 | 14:02h | UTC

Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial – European Heart Journal

 

Commentary on Twitter

 


M-A | Placebo response and media attention in randomized clinical trials assessing cannabis-based therapies for pain.

1 Dec, 2022 | 14:06h | UTC

Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis – JAMA Network Open

News Release: Positive media coverage of cannabis studies regardless of therapeutic effect – Karolinska Institutet

Commentaries: 

Cannabis is no better than a placebo for treating pain – new research – The Conversation

Media Coverage, Placebo Response Linked to Pain Relief Seen in Cannabinoid Trials – Psychiatric News Alert

 

Commentary on Twitter

 


M-A | Efficacy and safety of COVID-19 inactivated vaccine.

1 Dec, 2022 | 14:00h | UTC

Efficacy and safety of COVID-19 inactivated vaccine: A meta-analysis – Frontiers in Medicine

 


Study shows smartwatch ECGs can detect left ventricular dysfunction.

1 Dec, 2022 | 13:59h | UTC

Prospective evaluation of smartwatch-enabled detection of left ventricular dysfunction – Nature Medicine (link to abstract – $ for full-text)

News Release: AI transforms smartwatch ECG signals into a diagnostic tool for heart failure – Mayo Clinic

Commentary: AI Accurately Detects LV Dysfunction Using Single-Lead Apple Watch ECG – TCTMD

 

Commentary on Twitter

 


Collection of Cochrane evidence on diagnosing tuberculosis.

1 Dec, 2022 | 13:56h | UTC

Collection of Cochrane evidence on diagnosing tuberculosis – Cochrane Library

 


Cohort Study | Excess oxygen administration during surgery is linked to an increased risk of postoperative organ injury.

1 Dec, 2022 | 13:55h | UTC

Oxygen administration during surgery and postoperative organ injury: observational cohort study – The BMJ

Editorial: Oxygen administration during general anaesthesia for surgery – The BMJ

News Release: Excess oxygen during surgery linked to higher risk of organ damage – BMJ Newsroom

Commentary: Perioperative oxygen administration: finding the sweet spot – The BMJ

 


Cohort Study | 1 in 3 patients with hemodynamically unstable pelvic fractures die.

1 Dec, 2022 | 13:54h | UTC

Association Between Hemorrhage Control Interventions and Mortality in US Trauma Patients With Hemodynamically Unstable Pelvic Fractures – JAMA Surgery (free for a limited period)

Invited Commentary: Nationwide Variation of Care for Patients With Bleeding Pelvic Fracture—An Opportunity to Rescue Better? – JAMA Surgery (free for a limited period)

Author Interview: Hemorrhage Control Interventions and Mortality in Trauma Patients With Hemodynamically Unstable Pelvic Fractures – JAMA

 

Commentary on Twitter

 


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