Daily Archives: November 23, 2022
RCT | Low-dose morphine did not significantly reduce the intensity of chronic breathlessness in patients with COPD.
23 Nov, 2022 | 14:09h | UTCEffect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Dyspnea—When a Sensation Becomes a Symptom – JAMA (free for a limited period)
See also: Visual Abstract
Commentary: Breathlessness in Patients with COPD isn’t Reduced with Daily Morphine – HCP Live
KDIGO 2022 Guideline for the prevention, diagnosis, evaluation, and treatment of Hepatitis C in chronic kidney disease.
23 Nov, 2022 | 14:11h | UTCExecutive Summary: KDIGO 2022 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease – Kidney International
Guideline Synopsis | Diagnosis and treatment of infertility in men.
23 Nov, 2022 | 14:08h | UTCDiagnosis and Treatment of Infertility in Men – JAMA (free for a limited period)
Original Guideline: AUA/ASRM Guideline: Diagnosis and treatment of infertility in men
RCT | Treatment of early Lyme Disease with doxycycline for 7 days is noninferior to treatment for 14 days.
23 Nov, 2022 | 14:06h | UTCTreatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: Shorter Duration of Antibiotics Noninferior for Lyme Disease – JAMA (free for a limited period)
Commentary on Twitter
New research: Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trialhttps://t.co/8lktc4gxzG pic.twitter.com/mP2e0Kn7C5
— The Lancet Infectious Diseases (@TheLancetInfDis) October 7, 2022
RCT | Impact of empagliflozin on decongestion in acute heart failure.
23 Nov, 2022 | 14:04h | UTCCommentary: Empagliflozin in Patients Hospitalized for Acute Heart Failure – EMPULSE – American College of Cardiology
Commentary on Twitter
What's the impact of empagliflozin on decongestion in acute heart failure? New insights from the EMPULSE trial in EHJ!https://t.co/O1MZTFPWCc#SGLT2 #decongestion #heartfailure #empagliflozin #cardiotwitter @escardio @ESC_Journals pic.twitter.com/QLJYNgl1Zo
— EHJ Editor-in-Chief (@ehj_ed) October 19, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Cohort Study | Race-dependent association of HDL-C levels with incident coronary artery disease.
23 Nov, 2022 | 14:02h | UTCNews Release: Study challenges “good” cholesterol’s role in universally predicting heart disease risk – National Institutes of Health
Guideline | Screening and assessment of cancer-related fatigue.
23 Nov, 2022 | 13:58h | UTC
RCT | Effects of a physical exercise intervention during vs. after chemotherapy to improve cardiorespiratory fitness.
23 Nov, 2022 | 14:01h | UTCEditorial: Inclusion of Exercise in Cancer Treatment Planning: When Is the Right Time? – JACC: CardioOncology
Commentary: Exercise Intervention During Chemotherapy Beneficial – HealthDay
Cohort Study | Polygenic risk score improves the accuracy of a clinical risk score for coronary artery disease.
23 Nov, 2022 | 13:55h | UTCRelated:
AHA Scientific Statement | Polygenic risk scores for cardiovascular disease.
Cohort Study | Polygenic risk, midlife life’s simple 7, and lifetime risk of stroke.
Cohort Study: A polygenic risk score may improve risk stratification of coronary artery disease.
Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.
Commentary on Twitter
A #Polygenic risk score improves the accuracy of a clinical risk score for #CoronaryArteryDisease
Read more about improved predictive accuracy for incident CAD in the #UKBiobank at #BMCMedicine https://t.co/8T5RaacnTj pic.twitter.com/vIhg9IGhRv
— BMC Medicine (@BMCMedicine) November 8, 2022
Cohort Study | Prognostic prediction of genotype vs. phenotype in genetic cardiomyopathies.
23 Nov, 2022 | 13:57h | UTC
Commentary on Twitter
We are out with our last big work on the importance of genotype for the prognostic stratification of Cardiomyopathies! @CardiologyASUGI @Trieste_Denver @JACCJournals @PaldinoAlessia https://t.co/82byVNnUhK pic.twitter.com/KYoxDXkzr6
— matteo dal ferro (@matteodalferro) November 17, 2022
Under a Creative Commons license
Right heart failure in the ED: approach to diagnosis and management.
23 Nov, 2022 | 13:54h | UTCRight Heart Failure in the ED: Approach to Diagnosis and Management – emDocs
M-A | Acupuncture for low back and/or pelvic pain during pregnancy.
23 Nov, 2022 | 13:52h | UTCNews Release: Acupuncture can relieve lower back/pelvic pain often experienced during pregnancy – BMJ Newsroom
Cohort Study | Association of pregnancy characteristics and maternal mortality with amniotic fluid embolism.
23 Nov, 2022 | 13:51h | UTCInvited Commentary: Toward Risk Assessment for Amniotic Fluid Embolisms – JAMA Network Open
Commentary on Twitter
Amniotic fluid embolism is an uncommon pregnancy complication but is associated with dismal maternal outcome. The observed association between placenta accreta spectrum and amniotic fluid embolism in this study warrants further investigation. https://t.co/0zl2CMeHcy #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 18, 2022
RCT | Posterior cervical foraminotomy is noninferior to anterior cervical discectomy in patients with cervical radiculopathy.
23 Nov, 2022 | 13:48h | UTCNoninferiority of Posterior Cervical Foraminotomy vs Anterior Cervical Discectomy With Fusion for Procedural Success and Reduction in Arm Pain Among Patients With Cervical Radiculopathy at 1 Year: The FACET Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Commentary on Twitter
This study found noninferiority of posterior surgery compared to anterior surgery for patients with cervical radiculopathy in terms of success rate and arm pain at 1-year. https://t.co/Vdff9A7eGV #Research
— JAMA Neurology (@JAMANeuro) November 21, 2022
M-A | Is early laparoscopic cholecystectomy after clearance of common bile duct stones by ERCP superior?
23 Nov, 2022 | 13:44h | UTC
M-A | Optimal timing of anterior cruciate ligament reconstruction in patients with anterior cruciate ligament tear.
23 Nov, 2022 | 13:43h | UTC
Commentary on Twitter
This systematic review and meta-analysis suggests that early ACL repair has no overall superiority over elective delayed ACL repair, regardless of the follow-up duration. https://t.co/NEKwLzm6cl #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 17, 2022
SR | Follicular flushing during oocyte retrieval in assisted reproductive techniques.
23 Nov, 2022 | 13:46h | UTCFollicular flushing during oocyte retrieval in assisted reproductive techniques – Cochrane Library
Commentary on Twitter
Updated #review! We are uncertain of the effect of follicular flushing on live birth rate and miscarriage rate compared to aspiration alone @exgeorgiou @meloordep @CochraneLibraryhttps://t.co/VoORVrg8X4#infertility #IVF pic.twitter.com/qmZdHWAGDm
— Cochrane Gynaecology & Fertility (@CochraneCGF) November 21, 2022
RCT | Simvastatin is ineffective as a disease-modifying treatment for patients with Parkinson’s Disease.
23 Nov, 2022 | 13:42h | UTCCommentary: Simvastatin Ineffective as Disease-Modifying Therapy for Intermediate Parkinson Disease – AJMC
Commentary on Twitter
In a randomized clinical trial, #simvastatin was futile as a disease-modifying therapy in UK patients with moderate #ParkinsonDisease. https://t.co/etNsG7b3fI @Pen_CTU @NIHRSW @CureParkinsonsT @UHP_NHS @PlymUni
— JAMA Neurology (@JAMANeuro) November 1, 2022
RCT | Efficacy and safety of Remibrutinib, a novel BTK inhibitor, for chronic spontaneous urticaria.
23 Nov, 2022 | 13:37h | UTC
SR | Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee.
23 Nov, 2022 | 13:40h | UTC
Commentary on Twitter
New Cochrane Review ??
? "Compared with land-based exercise therapy, additional therapies plus exercise therapy, may not be more effective in improving pain, physical function, quality of life or joint changes."https://t.co/AU2LuyTwg8 pic.twitter.com/k2HYBMpJXp
— Physio Meets Science (@PhysioMeScience) October 17, 2022
RCT | Discontinuation vs. continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis.
23 Nov, 2022 | 13:36h | UTC
Commentary on Twitter
NEW Article—Discontinuing daily hypertonic saline or dornase alfa in #CFTR modulator-treated individuals with #cysticfibrosis: the SIMPLIFY study
From Nicole Mayer-Hamblett & colleagues https://t.co/LwVctcOlTq#NACFC2022 @CF_Foundation pic.twitter.com/OnDe8rUoPx
— The Lancet Respiratory Medicine (@LancetRespirMed) November 4, 2022