Daily Archives: November 22, 2022
SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.
22 Nov, 2022 | 13:39h | UTCSummary: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
Blood pressure targets in people with cardiovascular disease
Updated @CochraneHTN review looks at the evidence from 7 studies with 9595 people.
? #plainlanguage summary & #systematicreview available on the @CochraneLibrary https://t.co/dKYyoY773f— Cochrane UK (@CochraneUK) November 19, 2022
M-A | Use of CT of the head in patients with acute atraumatic altered mental status.
22 Nov, 2022 | 13:38h | UTC
Commentary on Twitter
Meta-analysis: 94% of patients with atraumatic altered mental status received a noncontrast CT head, with an average yield of 11% which varied by setting: 18% in ED patients, 12% of ICU patients, and 3% of general inpatients had positive findings on CT. https://t.co/yHWj6uSwTM
— JAMA Network Open (@JAMANetworkOpen) November 18, 2022
M-A | Balloon catheters vs. vaginal prostaglandins for labor induction.
22 Nov, 2022 | 13:35h | UTCBalloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)
Commentary: Balloon labor induction safer for babies, researchers find – Monash University
Commentary on Twitter (thread – click for more)
Globally, tens of millions of #pregnant women undergo labour induction each year.
A new study compares the effectiveness & safety of two common labour induction methods: balloon catheters & vaginal prostaglandins. ? pic.twitter.com/2c3WmC8Gvg
— The Lancet (@TheLancet) November 15, 2022
Guardianship | A medicolegal review for clinicians.
22 Nov, 2022 | 13:33h | UTCGuardianship: A medicolegal review for clinicians – Journal of the American Geriatrics Society
Cohort Study | Delayed intracranial hemorrhage after head injury among elderly patients on anticoagulation seen in the ED.
22 Nov, 2022 | 13:31h | UTCRelated:
Research: Incidence of Delayed Intracranial Hemorrhage in Older Patients After Blunt Head Trauma
2ry analysis of a RCT | Effect of Atogepant for preventive migraine treatment on patient-reported outcomes.
22 Nov, 2022 | 13:32h | UTCOriginal Study: Atogepant for the Preventive Treatment of Migraine – New England Journal of Medicine
M-A | Bioresorbable scaffolds vs. drug-eluting stents for patients with myocardial infarction.
22 Nov, 2022 | 13:29h | UTC
M-A | Indocyanine green fluorescence in patients undergoing laparoscopic colorectal cancer surgery.
22 Nov, 2022 | 13:25h | UTC
Cross-sectional study | Subretinal drusenoid deposits are strongly associated with coexistent high-risk vascular diseases.
22 Nov, 2022 | 13:27h | UTCCommentaries:
Specific AMD Phenotypes Strongly Associated with High-Risk Cardiovascular Disease – HCP Live
Subretinal Drusenoid Deposits Linked to High-Risk Vascular Disease in AMD – HealthDay
SR | Pharmaceutical interventions for emotionalism after stroke.
22 Nov, 2022 | 13:24h | UTCPharmaceutical interventions for emotionalism after stroke – Cochrane Library
SR | Early vitrectomy for exogenous endophthalmitis following surgery.
22 Nov, 2022 | 13:20h | UTCEarly vitrectomy for exogenous endophthalmitis following surgery – Cochrane Library
M-A | Cardiac and kidney adverse effects of HIF Prolyl-Hydroxylase inhibitors for anemia in patients with CKD not receiving dialysis.
22 Nov, 2022 | 13:22h | UTC
RCT | Subcutaneous vs. transvenous implantable cardioverter defibrillator implantations.
22 Nov, 2022 | 13:19h | UTCPerioperative Safety and Early Patient and Device Outcomes Among Subcutaneous Versus Transvenous Implantable Cardioverter Defibrillator Implantations: A Randomized, Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Subcutaneous ICD Reduces Lead-Related Complications – HealthDay
Related:
Subcutaneous or Transvenous Defibrillator Therapy – New England Journal of Medicine
Commentary on Twitter
New from @PHRIresearch @McMasterU: S-ICDs reduce lead-related complications by 92% w/out compromising effectiveness of shocks, but trend towards more inappropriate shocks: https://t.co/i7TtRr0PqP pic.twitter.com/Jhp7uprJT7
— Annals of Int Med (@AnnalsofIM) November 8, 2022
2ry analysis of a RCT | Device-related complications in subcutaneous versus transvenous ICD.
22 Nov, 2022 | 13:16h | UTCOriginal Study: Subcutaneous or Transvenous Defibrillator Therapy – New England Journal of Medicine
Related: Perioperative Safety and Early Patient and Device Outcomes Among Subcutaneous Versus Transvenous Implantable Cardioverter Defibrillator Implantations: A Randomized, Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Post-trial follow-up | Long-term outcomes of adjuvant denosumab in breast cancer.
22 Nov, 2022 | 13:14h | UTCLong-Term Outcomes of Adjuvant Denosumab in Breast Cancer – NEJM Evidence
Original Study: Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
RCT | Leniolisib for Activated phosphoinositide 3-kinase delta syndrome.
22 Nov, 2022 | 13:12h | UTC
M-A | Effects of Tai Chi and Qigong on the mobility of stroke survivors.
22 Nov, 2022 | 13:10h | UTC
18F-sodium fluoride PET–CT vs. 99mTc bone scintigraphy with SPECT in patients with prostate cancer or breast cancer.
22 Nov, 2022 | 13:09h | UTCIntra-individual comparison of 18F-sodium fluoride PET–CT and 99mTc bone scintigraphy with SPECT in patients with prostate cancer or breast cancer at high risk for skeletal metastases (MITNEC-A1): a multicentre, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary: 18F-NaF PET-CT More Accurate Than 99mTc-MDP SPECT for Detecting Bone Metastasis – Cancer Therapy Advisor
M-A | Burden of respiratory syncytial virus infection in older and high-risk adults in developed countries.
22 Nov, 2022 | 13:05h | UTC
Post-trial follow-up | A brief intervention to prevent alcohol use can have sustained effects among high-risk adolescents.
22 Nov, 2022 | 13:08h | UTC
Commentary on Twitter
RCT: Personality-targeted school-based prevention program “Preventure” can effectively reduce alcohol-related harms up to 7 years later, showing the meaningful & sustained benefits of school-based prevention programs. @theMatilda_USyd https://t.co/HuoZZluc6I #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 17, 2022
RCT | Zanubrutinib vs. Ibrutinib in relapsed/refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma.
22 Nov, 2022 | 13:03h | UTC
Pooled analysis of 4 studies | Drug-coated balloons vs. bare metal stents in patients with femoropopliteal arterial disease.
22 Nov, 2022 | 13:02h | UTC
PSMA and FDG-PET as predictive and prognostic biomarkers in patients given radioisotope therapy for prostate cancer.
22 Nov, 2022 | 12:56h | UTCPSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu]Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate cancer (TheraP): a biomarker analysis from a randomised, open-label, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary: PSMA-PET SUVmean Linked With Favorable Response to 177Lu-PSMA-617 in mCRPC – Targeted Oncology
RCT | New drug can improve constipation in patients with Parkinson Disease.
22 Nov, 2022 | 13:00h | UTCOral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
New Drug Could Ease Parkinson’s-Related Constipation – HealthDay
Commentary on Twitter
A #RTC of 150 persons with #ParkinsonDisease has found that ENT-01 is safe for up to 25 days of treatment and significantly improves constipation and possibly neurological symptoms: https://t.co/JdDhaHiFOA @MayoClinic pic.twitter.com/IWWCBzvrWV
— Annals of Int Med (@AnnalsofIM) November 8, 2022