Daily Archives: November 16, 2022 | LinksMedicus Free Medical News & Perspectives

USPSTF Statement | There is insufficient evidence to recommend routine screening for obstructive sleep apnea.

16 Nov, 2022 | 13:46h | UTC

Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement – JAMA

Evidence Report: Screening for Obstructive Sleep Apnea in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Editorial: USPSTF Updates Recommendation for Obstructive Sleep Apnea Screening in Adults – JAMA Otolaryngology—Head & Neck Surgery

JAMA Patient Page: Screening for Obstructive Sleep Apnea

Author Interview: USPSTF Recommendation: Screening for Obstructive Sleep Apnea in Adults

Commentary: USPSTF: Evidence Inadequate for Recommending OSA Screening – HealthDay

RCT | In patients with end-stage ankle osteoarthritis, total ankle replacement and arthrodesis resulted in comparable results.

16 Nov, 2022 | 13:45h | UTC

Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Trial shows benefits of two forms of ankle surgery for osteoarthritis – University College London

Summary for Patients: Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis

M-A | A short course of antibiotics is noninferior to long-course therapy in children with nonsevere pneumonia.

16 Nov, 2022 | 13:43h | UTC

Short-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)

Commentary: Review: Shorter antibiotic course sufficient for kids with pneumonia – CIDRAP

RCT | Among neonates with probable bacterial infection, switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) was noninferior to a full course of intravenous antibiotics and resulted in shorter hospitalization (median duration of 3.4 vs. 6.8 days).

RCT: In children with community-acquired pneumonia, outpatient antibiotic therapy for 5 days resulted in similar clinical response rates compared to a standard 10-day strategy.

ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections

RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia

RCT: Among children with community-acquired pneumonia discharged within 48 hours from the ED or hospital, lower-dose outpatient oral amoxicillin was noninferior to a higher dose, and a 3-day duration course was noninferior to 7 days.

Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review – short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

Randomized Trial: Seven vs. Fourteen Days of Antibiotic Therapy for Uncomplicated Gram-negative Bacteremia

Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

RCT | Comparative effects of low-dose rosuvastatin vs. dietary supplements on lipids and inflammatory biomarkers.

16 Nov, 2022 | 13:41h | UTC

Comparative Effects of Low-Dose Rosuvastatin, Placebo and Dietary Supplements on Lipids and Inflammatory Biomarkers – Journal of the American College of Cardiology

News Release: 6 common “heart-health” supplements ineffective at lowering cholesterol compared to statins – American Heart Association

Commentaries:

Study – For Lowering Cholesterol, Statins Work, Supplements Don’t – Science-Based Medicine

Statins vs. supplements: New study finds one is ‘vastly superior’ to cut cholesterol – NPR

Editorial | Agitated patients in the intensive care unit: guidelines for causal rather than symptomatic treatment are warranted.

16 Nov, 2022 | 13:37h | UTC

Agitated Patients in the Intensive Care Unit: Guidelines for Causal Rather Than Symptomatic Treatment are Warranted – Journal of Intensive Care Medicine

Mineralocorticoid dysfunction during critical illness: a review of the evidence.

16 Nov, 2022 | 13:36h | UTC

Mineralocorticoid Dysfunction during Critical Illness: A Review of the Evidence – Anesthesiology

Commentary on Twitter

https://twitter.com/_Anesthesiology/status/1559925866892779520

SR | Immunostimulants vs. placebo for preventing exacerbations in adults with chronic bronchitis or COPD.

16 Nov, 2022 | 13:34h | UTC

Immunostimulants versus placebo for preventing exacerbations in adults with chronic bronchitis or chronic obstructive pulmonary disease – Cochrane Library

Summary: Is taking an immunostimulant on top of standard medications beneficial for people with chronic obstructive pulmonary disease, chronic bronchitis, or both? – Cochrane Library

Guideline | Peri-operative management of neuromuscular blockade.

16 Nov, 2022 | 13:38h | UTC

Peri-operative management of neuromuscular blockade: A guideline from the European Society of Anaesthesiology and Intensive Care – European Journal of Anaesthesiology

SR | Masks vs. prongs as interfaces for nasal continuous positive airway pressure in preterm infants.

16 Nov, 2022 | 13:31h | UTC

Masks versus prongs as interfaces for nasal continuous positive airway pressure in preterm infants – Cochrane Library

Summary: Nasal masks versus nasal prongs for continuous positive airway pressure in preterm infants – Cochrane Library

Cohort Study | Childhood adversity and cardiovascular disease in early adulthood.

16 Nov, 2022 | 13:29h | UTC

Childhood adversity and cardiovascular disease in early adulthood: a Danish cohort study – European Heart Journal (free for a limited period)

Commentary: Study explores the links between childhood adversity and cardiovascular disease in early adulthood – European Society of Cardiology/News Medical

Commentary from the author on Twitter

https://twitter.com/HulvejRod/status/1592520830155886593

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