Daily Archives: August 11, 2022
RCT | Removal of small, asymptomatic kidney stones and incidence of relapse.
11 Aug, 2022 | 12:23h | UTCRemoval of Small, Asymptomatic Kidney Stones and Incidence of Relapse – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Removal of small, asymptomatic kidney stones during surgery to remove ureteral or contralateral stones resulted in less relapse than nonremoval and in similar numbers of subsequent emergency department visits. https://t.co/MRgFUnF1C0 pic.twitter.com/19ahPuHyNS
— NEJM (@NEJM) August 10, 2022
Review | How can assessing hemodynamics help to assess volume status?
11 Aug, 2022 | 12:21h | UTCHow can assessing hemodynamics help to assess volume status? – Intensive Care Medicine (free for a limited period)
Review | Machines that save lives in the intensive care unit: the ultrasonography machine.
11 Aug, 2022 | 12:20h | UTCMachines that save lives in the intensive care unit: the ultrasonography machine – Intensive Care Medicine (if the link is paywalled, try this one in PMC)
Commentary on Twitter
Ultrasonography saves lives in #ICU!!
? CCUS in constraints: utility in limited resource environment
? machine design for under‐resourced vs well‐resourced ICU
? training challenges
? evidence: does CCUS really save lives?#POCUS #FOAMcc #FOAMus
? https://t.co/Ht5tCPEyny pic.twitter.com/QacQcYYV4X— Intensive Care Medicine (@yourICM) August 9, 2022
RCT | In older patients undergoing total intravenous anesthesia, Etomidate is noninferior to Propofol regarding the risk of major postoperative complications.
11 Aug, 2022 | 12:18h | UTC
Commentary on Twitter
General anesthesia with etomidate does not increase postoperative morbidity, as indicated by the rate of major in-hospital post-op complications, in elderly patients undergoing abdominal surgery, as compared with propofol. https://t.co/vjPvle3DQj pic.twitter.com/2k6eSLupbH
— JAMA Surgery (@JAMASurgery) August 10, 2022
RCT | Tobramycin inhalation solution is effective in adults with bronchiectasis with pseudomonas aeruginosa infection.
11 Aug, 2022 | 12:15h | UTCCommentary: Tobramycin Tames Infection in Bronchiectasis – Medscape (free registration required)
Trauma care in older people: charting a path from outlier to excellence.
11 Aug, 2022 | 12:16h | UTCTrauma care in older people: charting a path from outlier to excellence – Age and Ageing
Cohort Study | Risk of hip fracture in meat-eaters, pescatarians, and vegetarians.
11 Aug, 2022 | 12:11h | UTCNews Release: Vegetarian women are at a higher risk of hip fracture – University of Leeds
Consensus Statement | Pharmacological management of allergic rhinitis.
11 Aug, 2022 | 12:10h | UTCRelated:
RCT | Effect of intranasal Dexmedetomidine or Midazolam for premedication on the occurrence of respiratory adverse events in children undergoing tonsillectomy and adenoidectomy.
11 Aug, 2022 | 12:08h | UTCCommentaries:
Dexmedetomidine Cuts Perioperative Respiratory AEs in Tonsillectomy – HealthDay
Commentary on Twitter
Children often required sedatives before surgery due to anxiety and crying. In this RCT, intranasal midazolam increased the incidence of perioperative respiratory adverse events (PRAEs), while intranasal dexmedetomidine reduced PRAEs. #OrigInvestigation https://t.co/5AAILuzstM pic.twitter.com/WejpGkAGGs
— JAMA Network Open (@JAMANetworkOpen) August 9, 2022
RCT | Low-dose Decitabine vs. low-dose Azacitidine in lower-risk myelodysplastic syndromes.
11 Aug, 2022 | 12:04h | UTCLow-Dose Decitabine versus Low-Dose Azacitidine in Lower-Risk MDS – NEJM Evidence
Commentary on Twitter
Low dose hypomethylating agent therapy led to an overall response rate of 60% in pts with low- or intermediate-risk myelodysplastic syndromes or chronic myelomonocytic leukemia who had not received prior hypomethylating agents. https://t.co/OSpNLzfiKW#MDS #LeuSM #CMML pic.twitter.com/BN1XAhfUBo
— NEJM Evidence (@NEJMEvidence) August 9, 2022
RCT | Effect of adjunctive acupuncture on pain relief among emergency department patients with acute renal colic due to urolithiasis.
11 Aug, 2022 | 12:06h | UTCCommentary: Adjunctive Acupuncture May Speed Relief From Pain of Renal Colic – HealthDay
Commentary on Twitter
In this #RCT of emergency department patients with renal colic who received IM NSAIDs, acupuncture provided additional fast short-term pain relief for compared with sham acupuncture. #OrigInvestigation https://t.co/7i2wk86hif pic.twitter.com/VHNDFqOcOx
— JAMA Network Open (@JAMANetworkOpen) August 9, 2022
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions.
11 Aug, 2022 | 12:02h | UTC
Commentary on Twitter
Extracorporeal carbon dioxide removal #ECCO2r: to date indications & risk-to-beneft ratio of this technique should now be carefully evaluated using structured national or international registries and large randomized trials. Here #FOAMcc narrative review
?️https://t.co/CN8OSha8uY https://t.co/zEFBMAF9dW pic.twitter.com/QqPG00QKPU— Intensive Care Medicine (@yourICM) August 10, 2022
Systematic Review | Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.
11 Aug, 2022 | 11:59h | UTCInhaled antibiotics for pulmonary exacerbations in cystic fibrosis – Cochrane Library
RCT | Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension.
11 Aug, 2022 | 11:57h | UTCCommentary: Topical Dexamethasone Ophthalmic Suspension OCS-01 Effective in DME Treatment – HCP Live
Single-center phase 2 trial | Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas.
11 Aug, 2022 | 11:52h | UTCDurvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Online first: #Durvalumab plus #tremelimumab in advanced or metastatic soft tissue and bone #sarcomas: a single-centre phase 2 trial https://t.co/Zt9vTFzBOK pic.twitter.com/BP7fz9FWRw
— The Lancet Oncology (@TheLancetOncol) August 5, 2022
Cohort Study | Association of gonadotropin-releasing hormone agonists for prostate cancer with cardiovascular disease risk and hypertension in men with diabetes.
11 Aug, 2022 | 11:54h | UTC
Commentary on Twitter
Study showed men with #T2DM on GnRH for prostate cancer had a 53% higher risk of an increase in CVD risk score than those not on GnRH, suggesting the need to control cardiovascular disease risk factors in men with T2DM receiving GnRH. #OrigInvestigation https://t.co/3cJ10PpQGN
— JAMA Network Open (@JAMANetworkOpen) August 8, 2022
M-A | Use of folic acid supplementation to halt and even reverse the progression of gastric precancerous conditions.
11 Aug, 2022 | 11:51h | UTCCommentary: Can Folic Acid Halt or Reverse Progression of Gastric Precancerous Conditions? – Medscape (free registration required)
Cohort Study | Recurrence of axial spondyloarthritis among first-degree relatives in a prospective 35-year-follow-up family study.
11 Aug, 2022 | 11:47h | UTCCommentary: Substantial lifetime risk for axSpA among relatives of patients with ankylosing spondylitis – medwire News
Commentary on Twitter
The frequency of first-degree relatives from HLA B27+ patients with #ankylosingspondylitis to also have was 27.1% in a 35-year follow-up study from ?? Mothers with AS were more likely than fathers to pass on the risk to their children. https://t.co/iRGux3lXvm pic.twitter.com/KBzyRZnjQN
— ARD & RMD Open (@ARD_BMJ) July 24, 2022
Cohort Study | Neonatal outcomes of mothers with a disability.
11 Aug, 2022 | 11:49h | UTCNeonatal Outcomes of Mothers With a Disability – Pediatrics
Commentary: Risk for Complications Increased for Newborns of Moms With Disability – HealthDay