Daily Archives: August 9, 2022
RCT | Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity.
9 Aug, 2022 | 12:59h | UTCAuthor Interview: Effectiveness of Early Time-Restricted Eating for Weight Loss and Fat Loss in Adults With Obesity – JAMA
Commentaries:
Time-Restricted Eating to Improve Health—A Promising Idea in Need of Stronger Clinical Trial Evidence – JAMA Internal Medicine (free for a limited period)
Related:
Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition
Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link to abstract – $ for full-text)
AAP Guideline Update | Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.
9 Aug, 2022 | 13:00h | UTC
RCT | Hughes abdominal closure vs. standard mass closure to reduce incisional hernias following surgery for colorectal cancer.
9 Aug, 2022 | 12:56h | UTC
M-A | Global prevalence and incidence of tinnitus.
9 Aug, 2022 | 12:57h | UTCGlobal Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Commentary: Review: Global Pooled Prevalence of Tinnitus 14.4 Percent – HealthDay
Commentary on Twitter
The global burden of #tinnitus is large, similar to #migraine and pain, and the lack of effective treatment options justifies a major investment in research in this area. https://t.co/9uVJmnYh9c
— JAMA Neurology (@JAMANeuro) August 8, 2022
Guideline Synopsis | Treatment of Clostridioides difficile infection.
9 Aug, 2022 | 12:54h | UTCTreatment of Clostridioides difficile Infection – JAMA (free for a limited period)
Original Guideline: ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections – American Journal of Gastroenterology
Related Guidelines:
Commentary on Twitter
A summary of @AmCollegeGastro’s 2021 guidelines on treatment of Clostridioides difficile infection. https://t.co/QzrMa71ttu
— JAMA (@JAMA_current) August 8, 2022
Diagnostic Test Interpretation | Serum Cystatin C for estimation of glomerular filtration rate.
9 Aug, 2022 | 12:52h | UTCSerum Cystatin C for Estimation of GFR – JAMA (free for a limited period)
Commentary on Twitter
An 80-year-old man with #type2diabetes and #hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his ACE inhibitor. #JAMADiagnosticTestInterpretation https://t.co/kxg0yHeGUr
— JAMA (@JAMA_current) August 8, 2022
Changes to the European Resuscitation Council guidelines for adult resuscitation.
9 Aug, 2022 | 12:50h | UTCChanges to the European Resuscitation Council guidelines for adult resuscitation – BJA Education
Related:
2021 Resuscitation Guidelines – Resuscitation Council UK
RCT | Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast.
9 Aug, 2022 | 12:46h | UTCRadiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01): a randomised, factorial, multicentre, open-label, phase 3 study – The Lancet (link to abstract – $ for full-text)
RCT | Effect of a comprehensive telehealth intervention vs. telemonitoring and care coordination in patients with persistently poor type 2 diabetes control.
9 Aug, 2022 | 12:44h | UTCEffect of a Comprehensive Telehealth Intervention vs Telemonitoring and Care Coordination in Patients With Persistently Poor Type 2 Diabetes Control: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A comprehensive telehealth intervention improved HbA1c in persistently poorly-controlled type 2 diabetes compared to a simpler telehealth intervention; the comprehensive telehealth approach may warrant implementation in systems with appropriate resources. https://t.co/qXnuclyipQ
— JAMA Internal Medicine (@JAMAInternalMed) July 29, 2022
Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.
9 Aug, 2022 | 12:42h | UTCSmoking cessation for secondary prevention of cardiovascular disease – Cochrane Library
M-A | Immunogenicity, safety, and efficacy of the HPV vaccines among people living with HIV.
9 Aug, 2022 | 12:41h | UTC
RCT | Efficacy and safety of intravenous acetaminophen (2 g/day) for reducing opioid consumption in Chinese adults after elective orthopedic surgery.
9 Aug, 2022 | 12:39h | UTC
M-A | Management of neovascular glaucoma.
9 Aug, 2022 | 12:37h | UTC
Inhaled antibiotics in critical care: state of the art and future perspectives.
9 Aug, 2022 | 12:30h | UTC
RCT | Effectiveness of Varenicline and Cytisine for alcohol use reduction among people with HIV and substance use.
9 Aug, 2022 | 12:35h | UTC
Commentary on Twitter
In this RCT, varenicline and cytisine were not more efficacious than nicotine to treat risky drinking and smoking among individuals with HIV; rates of behavior change for alcohol consumption and smoking were high in all treatment groups. #OrigInvestigation https://t.co/h8M6e5nOkf
— JAMA Network Open (@JAMANetworkOpen) August 5, 2022
Review | Role of imaging in CNS infections.
9 Aug, 2022 | 12:26h | UTCRole of imaging in CNS infections – Indian Journal of Pathology & Microbiology
Systematic Review | Diabetes mellitus and perioperative outcomes.
9 Aug, 2022 | 12:28h | UTC
RCT | Palliative radiation for advanced central lung tumors with intentional avoidance of the esophagus.
9 Aug, 2022 | 12:24h | UTCCommentary: Esophagus-Sparing Radiation Fails QOL Test in Lung Cancer— Esophageal-specific quality of life no better, but treatment reduced symptomatic esophagitis – MedPage Today (free registration required)
Commentary on Twitter
PROACTIVE was a phase 3 RCT of 90 pts with incurable lung cancer treated with esophageal sparing IMRT vs. standard palliative RT. ES-IMRT did not improve FACT-E ECS quality of life scores at 2wks but reduced grade≥2 esophagitis (24% vs. 2%). https://t.co/ExIp22WBPe #RadOnc #LCSM pic.twitter.com/lX8lD4Duja
— JAMA Oncology (@JAMAOnc) February 24, 2022
Cohort Study | Impact of low versus negative estrogen/progesterone receptor status on clinico-pathologic characteristics and survival outcomes in HER2-negative breast cancer.
9 Aug, 2022 | 12:20h | UTC
Commentary on Twitter
Out on NPJ Breast a new report on #ERlowtumors. No difference in characteristics, pCR rates, RFS os OS compared with #TNBC. Patients with ER-low tumors should be treated as for TNBC. Also, important confounder to remember in HER2-low prognostic analyses.https://t.co/M1GF8eyYbT pic.twitter.com/CrLyUgyhUV
— Paolo Tarantino (@PTarantinoMD) July 11, 2022
Single-arm phase 2 study | Long-term follow-up of combination of B-Cell maturation antigen and CD19 chimeric antigen receptor T cells in multiple myeloma.
9 Aug, 2022 | 12:22h | UTCLong-Term Follow-Up of Combination of B-Cell Maturation Antigen and CD19 Chimeric Antigen Receptor T Cells in Multiple Myeloma – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary on Twitter
? Combination of anti-BCMA and anti-CD19 CAR T cells induced durable response in patients with relapsed/refractory #MultipleMyeloma ➡️ https://t.co/TkPRcTKSxg #JCO #MMSM pic.twitter.com/0OZAJtTXF1
— Journal of Clinical Oncology (@JCO_ASCO) April 15, 2022