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Daily Archives: June 6, 2022

Updated WHO recommendations for malaria chemoprevention and elimination.

6 Jun, 2022 | 12:07h | UTC

News Release: Updated WHO recommendations for malaria chemoprevention and elimination – World Health Organization

Original Document: WHO Guidelines for malaria – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

Oncologic emergencies and urgencies: A comprehensive review.

6 Jun, 2022 | 12:06h | UTC

Oncologic emergencies and urgencies: A comprehensive review – CA: A Cancer Journal for Clinicians

 

Commentary on Twitter

 

#ADA2022 – ADA Consensus Report | Heart Failure: An underappreciated complication of diabetes.

6 Jun, 2022 | 12:02h | UTC

Heart Failure: An Underappreciated Complication of Diabetes. A Consensus Report of the American Diabetes Association – Diabetes Care

 

#ADA2022 – RCT: Tirzepatide once weekly for the treatment of obesity.

6 Jun, 2022 | 11:59h | UTC

Tirzepatide Once Weekly for the Treatment of Obesity – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: SURMOUNT-1 Study Finds Individuals with Obesity Lost up to 22.5% of their Body Weight when Taking Tirzepatide – American Diabetes Association

 

Commentary on Twitter

 

#ADA2022 – RCT: Once-weekly dulaglutide for the treatment of youths with type 2 diabetes.

6 Jun, 2022 | 11:57h | UTC

Once-Weekly Dulaglutide for the Treatment of Youths with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Once Weekly Drug Helps Control Pediatric Type 2 Diabetes – American Diabetes Association

 

Commentary on Twitter

 

#ASCO22 – RCT: Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer.

6 Jun, 2022 | 11:53h | UTC

Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: DNA shed from colon cancers into bloodstream successfully guides chemotherapy after surgery – Helps clarify the benefit of chemotherapy in stage II cancers – Johns Hopkins Medicine

Commentary: ctDNA Effectively Detects When Adjuvant Chemo Is Avoidable in Stage II Colon Cancers – Cancer Network

 

Commentary on Twitter

 

#ADA2022 – Retrospective Cohort Study: Association of bariatric surgery with cancer risk and mortality in adults with obesity.

6 Jun, 2022 | 11:54h | UTC

Association of Bariatric Surgery With Cancer Risk and Mortality in Adults With Obesity – JAMA (free for a limited period)

Editorial: Bariatric Surgery and Cancer Risk – JAMA (free for a limited period)

News Release: Weight loss with bariatric surgery cuts the risk of developing cancer and death from cancer – Cleveland Clinic

 

Commentaries on Twitter

 

#EULAR2022 – RCT: Low dose, add-on prednisolone in patients with rheumatoid arthritis over 65 years.

6 Jun, 2022 | 11:51h | UTC

Low dose, add-on prednisolone in patients with rheumatoid arthritis aged 65+: the pragmatic randomised, double-blind placebo-controlled GLORIA trial – Annals of Rheumatic Diseases

Commentaries:

Chronic, low-dose glucocorticoid benefits outweigh harms in senior patients with RA – medwire News

Trial Upends Guidelines on Long-Term Steroids in Rheumatoid Arthritis — Vindication for clinicians who ignored official recommendations – MedPage Today (free registration required)

 

Experts highlight sexual aspect of monkeypox spread.

6 Jun, 2022 | 11:39h | UTC

Experts highlight sexual aspect of monkeypox spread – CIDRAP

Related:

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 

Consensus Statement: Diagnostic action against hypertransaminasemia in pediatrics.

6 Jun, 2022 | 11:23h | UTC

Diagnostic action against hypertransaminasemia in paediatrics: Consensus document of Sociedad Española de Gastroenterología, Hepatología y Nutrición Pediátrica (SEGHNP), Asociación Española de Pediatría de Atención Primaria (AEPap) and Sociedad Española de Pediatría de Atención Primaria (SEPEAP) – Anales de Pediatría (English Edition)

 

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread.

6 Jun, 2022 | 11:42h | UTC

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

See also: 2 monkeypox strains in US suggest possible undetected spread – Associated Press

Related:

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 

Consensus Statement: Effect of carbohydrate-restricted diets and intermittent fasting on obesity, type 2 diabetes mellitus, and hypertension management.

6 Jun, 2022 | 11:22h | UTC

Effect of Carbohydrate-Restricted Diets and Intermittent Fasting on Obesity, Type 2 Diabetes Mellitus, and Hypertension Management: Consensus Statement of the Korean Society for the Study of Obesity, Korean Diabetes Association, and Korean Society of Hypertension – Diabetes & Metabolism Journal

See also: Comprehensive Understanding for Application in Korean Patients with Type 2 Diabetes Mellitus of the Consensus Statement on Carbohydrate-Restricted Diets by Korean Diabetes Association, Korean Society for the Study of Obesity, and Korean Society of Hypertension – Diabetes & Metabolism Journal

 

Guidelines for the Kaposi Sarcoma.

6 Jun, 2022 | 11:20h | UTC

S1 Guidelines for the Kaposi Sarcoma – Journal of the German Society of Dermatology

 

#ASCO22 – RCT: Trastuzumab Deruxtecan in previously treated HER2-low advanced breast cancer.

6 Jun, 2022 | 11:18h | UTC

Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Trastuzumab Deruxtecan Cuts Risk of Disease Progression or Death by 50% for Patients With HER2-Low Metastatic Breast Cancer – AJMC

 

Commentary on Twitter

 

#ASCO22 – RCT: Ibrutinib plus Bendamustine and Rituximab in untreated Mantle-Cell Lymphoma.

6 Jun, 2022 | 11:16h | UTC

Ibrutinib plus Bendamustine and Rituximab in Untreated Mantle-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Ibrutinib with chemoimmunotherapy improved progression-free survival for newly diagnosed mantle cell lymphoma patients – BTK inhibitor as front-line option for MCL – University of Texas M. D. Anderson Cancer Center

Commentary: Ibrutinib Added to Standard Therapy Prolongs Progression-Free Survival in Older Patients With Mantle Cell Lymphoma – The ASCO Post

 

Difficult and complicated oral ulceration: an expert consensus guideline for diagnosis.

6 Jun, 2022 | 11:19h | UTC

Difficult and complicated oral ulceration: an expert consensus guideline for diagnosis – International Journal of Oral Science

 

#ASCO22 – Phase 2 single-arm study: Adagrasib in non–small-cell lung cancer harboring a KRASG12C mutation.

6 Jun, 2022 | 11:15h | UTC

Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Targeted drug achieves 43% response rate in KRAS-mutated lung cancer – Dana-Farber Cancer Institute

 

#ASCO22 – Phase 2 single-arm study: PD-1 Blockade in mismatch repair–deficient, locally advanced rectal cancer.

6 Jun, 2022 | 11:12h | UTC

PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 

#ASCO22 – Phase II RCT: Ramucirumab and pembrolizumab vs. standard of care in advanced non–small-cell lung cancer previously treated with immunotherapy.

6 Jun, 2022 | 11:14h | UTC

Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non–Small-Cell Lung Cancer Previously Treated With Immunotherapy—Lung-MAP S1800A – Journal of Clinical Oncology

Commentary: New drug combination lengthened survival for some with lung cancer – SWOG Cancer Research Network

 

Commentary on Twitter

 

#ASCO22 – RCT: Triplet therapy, transplantation, and maintenance until progression in myeloma.

6 Jun, 2022 | 11:06h | UTC

Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Improved progression-free survival in multiple myeloma patients following three-drug therapy with autologous stem cell transplant – Dana-Farber Cancer Institute

 

Commentary on Twitter

 

#ASCO22 – Phase 1-2 single-arm study: Teclistamab in relapsed or refractory multiple myeloma.

6 Jun, 2022 | 11:11h | UTC

Teclistamab in Relapsed or Refractory Multiple Myeloma – New England Journal of Medicine

 

Commentary on Twitter

 

RCT: Computer-aided device improves adenoma detection in colonoscopy for screening and surveillance colonoscopy.

6 Jun, 2022 | 11:03h | UTC

Computer-Aided Detection Improves Adenomas per Colonoscopy for Screening and Surveillance Colonoscopy: A Randomized Trial – Gastroenterology

Commentary: Colonoscopy With a Computer-Aided Device Boosted Adenoma Detection — Use of the device led to a 27% increase in adenomas per colonoscopy versus standard procedure – MedPage Today (free registration required)

 

M-A: Routine abdominal drainage after distal pancreatectomy.

6 Jun, 2022 | 11:01h | UTC

Routine abdominal drainage after distal pancreatectomy: meta-analysis – British Journal of Surgery

 

Commentary on Twitter

 

RCT: Effect of intraoperative handovers of anesthesia care on mortality, readmission, or postoperative complications among adults.

6 Jun, 2022 | 11:04h | UTC

Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults: The HandiCAP Randomized Clinical Trial – JAMA (free for a limited period)

Related Study: Association Between Handover of Anesthesia Care and Adverse Postoperative Outcomes Among Patients Undergoing Major Surgery – JAMA

 

Commentary on Twitter

 

Cohort Study: Intrauterine device-related uterine perforation incidence and risk.

6 Jun, 2022 | 10:59h | UTC

Intrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 

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