Daily Archives: April 26, 2022
Covid-19: Only a quarter of patients admitted to hospital feel fully recovered after a year, study finds.
26 Apr, 2022 | 08:45h | UTCInvited Commentary: Long COVID: systemic inflammation and obesity as therapeutic targets – The Lancet Respiratory Medicine
Commentary on Twitter (thread – click for more)
PHOSP-COVID study:
– 232 (29%) of 804 pts fully recovered at 1y
– Female sex, obesity, & IMV = less likely to feel fully recovered
– inflamm mediators?in those w/ most severe physical, mental health, & cognitive impairmentsRead it here: https://t.co/rVZuVDo4xl
— The Lancet Respiratory Medicine (@LancetRespirMed) April 25, 2022
Persistent COVID-19 symptoms in a community study of 606,434 people in England.
26 Apr, 2022 | 08:48h | UTC
Commentary on Twitter
Thirty-eight percent of participants from a community-based study of symptoms following COVID-19 reported persistent symptoms that lasted 12 weeks or more, according to an article published in @NatureComms. https://t.co/sAEutdOkSS pic.twitter.com/oCyyXGIRbk
— Nature Portfolio (@NaturePortfolio) April 20, 2022
Cohort Study: Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations.
26 Apr, 2022 | 08:21h | UTCNews Release: Study suggests association between severe COVID-19 and long-term mental health outcomes 16 months after an illness – Lancet
Commentary: Lasting depression and anxiety can follow severe case of Covid – NBC News
Commentary on Twitter (thread – click for more)
In our study published in the @TheLancetPH, we found that a mild course of acute illness (never bedridden due to #COVID19) was associated with a persistently lower risk of adverse #mentalhealth outcomes. https://t.co/aHBQTaOi4K
Several factors might contribute to this pattern?
— COVIDMENT research project (@COVIDMENT) April 11, 2022
Practice Pointer: Making decisions about radiological imaging in pregnancy.
26 Apr, 2022 | 08:44h | UTCMaking decisions about radiological imaging in pregnancy – The BMJ
Yes, relapses after Paxlovid happen — now what?
26 Apr, 2022 | 08:18h | UTCYes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
Commentary on Twitter
Some additional thoughts about relapsing Covid19 after treatment with Paxlovid.
Bottom line — *lots* of unknowns, starting w/ how often it happens.
Looking forward to @pfizer sharing further data on the relapsing cases from their EPIC-HR study. https://t.co/1MMhqn4elw
— Paul Sax (@PaulSaxMD) April 25, 2022
M-A: Evaluation of the incremental value of a coronary artery calcium score beyond traditional cardiovascular risk assessment.
26 Apr, 2022 | 08:15h | UTCEvaluation of the Incremental Value of a Coronary Artery Calcium Score Beyond Traditional Cardiovascular Risk Assessment: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Addition of Coronary Artery Calcium Scores to Primary Prevention Risk Estimation Models—Primum Non Nocere – JAMA Internal Medicine (free for a limited period)
Author Interview: Incremental Value of a Coronary Artery Calcium Score
Commentary on Twitter
Coronary artery calcium scans provide a small gain in CVD risk assessment and may have a role in selected patients. Potential harms include false positives, incidental findings, radiation, and cost. No evidence suggests that this provides clinical benefit. https://t.co/7bASFf26NF
— JAMA Internal Medicine (@JAMAInternalMed) April 25, 2022
RCT: Uterine artery embolization vs. myomectomy for premenopausal women with uterine fibroids wishing to avoid hysterectomy.
26 Apr, 2022 | 08:08h | UTC
Why does the Omicron variant largely spare olfactory function? implications for the pathogenesis of anosmia in COVID-19.
26 Apr, 2022 | 08:05h | UTC
Cluster RCT: Supraglottic airway device vs. tracheal intubation in the initial airway management of out-of-hospital cardiac arrest.
26 Apr, 2022 | 08:12h | UTC
Cohort Study: Effectiveness of homologous vs. heterologous booster doses for an inactivated SARS-CoV-2 vaccine.
26 Apr, 2022 | 08:06h | UTCCommentaries:
COVID-19 vaccine booster strategy: striving for best practice – The Lancet Global Health
Covid-19: Mix and match booster vaccination approach offers best protection, study reports – The BMJ
Commentary on Twitter
Effectiveness of homologous and heterologous booster doses for an inactivated SARS-CoV-2 vaccine: a large-scale prospective cohort study https://t.co/0k7WlphoDV Heterologous booster provided ⬆️ protection than homologous one, especially when Coronavac vaccine had been used.
— Carlos del Rio (@CarlosdelRio7) April 25, 2022
Systematic Review: Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts.
26 Apr, 2022 | 07:52h | UTC
Guideline: Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure.
26 Apr, 2022 | 08:03h | UTC
Consensus for the treatment of tinea pedis.
26 Apr, 2022 | 08:02h | UTC
A therapeutic guide on pediatric irritable bowel syndrome and functional abdominal pain-not otherwise specified.
26 Apr, 2022 | 07:58h | UTC
Conclusions from a controversies conference: genetics in chronic kidney disease.
26 Apr, 2022 | 07:53h | UTC
M-A: Intensification of systemic therapy in addition to definitive local treatment in nonmetastatic unfavorable prostate cancer.
26 Apr, 2022 | 07:51h | UTC
Podcast: Curing Hepatitis C.
26 Apr, 2022 | 07:47h | UTC#329 Curing Hepatitis C – The Curbsiders
Podcast: Inpatient diabetes pearls.
26 Apr, 2022 | 07:48h | UTC#330 Inpatient Diabetes with Dr. Dave Lieb – The Curbsiders
RCT: Ten-year outcomes of off-pump vs. on-pump coronary artery bypass grafting.
26 Apr, 2022 | 07:45h | UTCTen-Year Outcomes of Off-Pump vs On-Pump Coronary Artery Bypass Grafting in the Department of Veterans Affairs: A Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
ROOBY-FS: 10-Year Data Affirm On-Pump CABG as Default Strategy – TCTMD
10-Year Study Results Find Patient Outcomes Similar for Two CABG Procedures – Stony Brook University
Commentary on Twitter
The @DeptVetAffairs ROOBY follow-up study compared off-pump versus on-pump ten-year post-CABG outcomes and costs. Across all endpoints, no off-pump advantage was found. Sensitivity analyses, removing conversions, confirmed these findings to be robust. https://t.co/IAcnxVHFWj
— JAMA Surgery (@JAMASurgery) February 16, 2022
Giant tube slides and broken legs: why the latest playground craze is a serious hazard.
26 Apr, 2022 | 07:50h | UTC
RCT: Supervised exercise therapy vs. endovascular revascularisation for intermittent claudication caused by iliac artery obstruction.
26 Apr, 2022 | 07:43h | UTC
RCT: Effectiveness of cognitive behavioral therapy–based intervention in preventing gaming disorder and unspecified internet use disorder in adolescents.
26 Apr, 2022 | 07:42h | UTCCommentaries:
The Case for Prevention Research in Adolescent-Onset Mental Illness—Game On! – JAMA Network Open
Commentary on Twitter
This RCT of at-risk high school students showed that a short school-based prevention program can reduce gaming disorder and internet use disorder symptoms. https://t.co/L9VhwaRVDG pic.twitter.com/Ix8WzUBSSZ
— JAMA Network Open (@JAMANetworkOpen) February 18, 2022
Critical analysis of the updated guidelines for management of gallbladder polyps.
26 Apr, 2022 | 07:41h | UTCCritical Analysis of the Updated Guidelines for Management of Gallbladder Polyps – Annals of Surgical Oncology (if the link is paywalled, try this one)
A comprehensive and comparative review of global gastric cancer treatment guidelines.
26 Apr, 2022 | 07:39h | UTC
Gout in the ED: Pearls and pitfalls.
26 Apr, 2022 | 07:37h | UTCGout in the ED: Pearls and Pitfalls – emDocs