Daily Archives: April 13, 2022
USPSTF draft statement recommends screening for anxiety and depression in children and adolescents ages 8 to 18 years.
13 Apr, 2022 | 11:05h | UTCDraft Statements:
Screening for Anxiety in Children and Adolescents – US Preventive Services Task Force
Commentary:
USPSTF Recommends Anxiety, Depression Screening for Children – HealthDay
The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019.
13 Apr, 2022 | 11:03h | UTCInvited Commentary: The burden of young people’s mental health conditions in Europe: No cause for complacency – The Lancet Regional Health Europe
Related:
Commentary on Twitter
See our new @IHME_UW analysis from on the #burden of #mentaldisorders, substance use disorders & self-harm among young people in Europe. In 2019 there were 16,983 MDs cases/100.000. In last 30 yrs YLD for eating disorders & drug use disorders increased. https://t.co/hMbHDlPuur pic.twitter.com/Rt4Iq4tpAA
— Maciej Banach (@maciejbanach) April 2, 2022
(Article and images under a CC BY 4.0 license)
Review: Diagnosis and treatment of pulmonary arterial hypertension.
13 Apr, 2022 | 10:58h | UTCDiagnosis and Treatment of Pulmonary Arterial Hypertension: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Treatment of Pulmonary Arterial Hypertension – JAMA
Commentary on Twitter
This review summarizes current evidence regarding diagnosis and treatment of pulmonary arterial #hypertension. https://t.co/Ebo33PD8Qq
— JAMA (@JAMA_current) April 12, 2022
RCT: A home-based, walking exercise behavior change intervention increased walking distance in adults with peripheral artery disease.
13 Apr, 2022 | 11:02h | UTCEffect of a Home-Based, Walking Exercise Behavior Change Intervention vs Usual Care on Walking in Adults With Peripheral Artery Disease: The MOSAIC Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this study, among adults with peripheral artery disease, a home-based, #walking #exercise behavior change intervention, compared with usual care, increased 6-minute walking distance at 3 months. https://t.co/5ea3YOWlN0 @LindsayBearne pic.twitter.com/s06ONnki9y
— JAMA (@JAMA_current) April 12, 2022
Perspective: The concept of classical herd immunity may not apply to COVID-19.
13 Apr, 2022 | 10:54h | UTCNews Release: NIH experts discuss controlling COVID-19 in commentary on herd immunity – NIH News Releases
Commentary on Twitter
Co-authored by Dr. Anthony Fauci and two other @NIAIDNews'ers
"We no longer need the elusive concept of 'herd immunity' as an aspirational goal: COVID-19 control is already within our grasp."https://t.co/kvYfpsXviB https://t.co/aaiGcb3qtL pic.twitter.com/6yrcsKbUGi
— Alexander Tin (@Alexander_Tin) March 31, 2022
Cluster RCT: A shorter antimicrobial prophylaxis duration (less than 24 hours after surgery) is noninferior to a more extended regimen (24-48 hours) after clean orthopedic surgery.
13 Apr, 2022 | 10:56h | UTC
Commentary on Twitter
Cluster RCT of patients who underwent clean orthopedic surgery found shorter antimicrobial prophylaxis duration (<24h postop) was noninferior to longer duration (<48h) in preventing health care associated infections and across a range of clinical outcomes. https://t.co/FFzxNiHxet
— JAMA Network Open (@JAMANetworkOpen) April 12, 2022
M-A: Sodium-glucose Cotransporter 2 inhibitors are associated with reduced risk of hyperkalemia in people with type 2 diabetes.
13 Apr, 2022 | 10:52h | UTC
RCT: Dapagliflozin did not significantly improve glycemic control in children and young adults with type 2 diabetes.
13 Apr, 2022 | 10:46h | UTCEfficacy and safety of dapagliflozin in children and young adults with type 2 diabetes: a prospective, multicentre, randomised, parallel group, phase 3 study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
RCT: Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis.
13 Apr, 2022 | 10:31h | UTCNews Release: Breakthrough success in provision of automated psychological therapy using virtual reality – University of Oxford
Commentary from the author on Twitter
gameChange results are out! Six sessions of automated VR therapy reduced agoraphobic avoidance and distress for patients with psychosis. People who were mainly housebound had large benefits maintained at 6mths. @OxPsychiatry @NIHRresearch @TheLancetPsych https://t.co/VE9oxsa5cf pic.twitter.com/KAvuLqHtiI
— Daniel Freeman (@ProfDFreeman) April 6, 2022
Review | Less is more: deprescribing medications in older adults with kidney disease.
13 Apr, 2022 | 10:44h | UTCLess is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Related:
AGA clinical practice update on de-prescribing of proton pump inhibitors.
Development of a metric to detect and decrease low-value prescribing in older adults.
Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.
A narrative review of evidence to guide deprescribing among older adults.
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan
Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
New insights into the genetic etiology of Alzheimer’s disease and related dementias.
13 Apr, 2022 | 10:26h | UTCNews Release:
Commentaries:
42 previously unknown genes discovered for Alzheimer’s disease – CNN
Alzheimer’s disease research takes ‘major leap forward’ – BBC
Commentary on Twitter
A meta-analysis in @NatureGenet of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia. https://t.co/EAtdlRozld pic.twitter.com/5rtWWt4HyS
— Nature Portfolio (@NaturePortfolio) April 11, 2022
Cluster RCT: A multifaceted intervention did not reduce catheter related bloodstream infections in patients on hemodialysis.
13 Apr, 2022 | 10:29h | UTC
Opinion | Time to rethink the scientific CV.
13 Apr, 2022 | 10:23h | UTCTime to rethink the scientific CV – Nature
Commentary on Twitter
As institutions and funders around the world reassess their approach to researcher evaluations, there’s a growing call to revamp the academic CVs used to support applications for jobs, funding, promotions and awards. Read the @NatureCareers feature. https://t.co/ZGxrJrA1ZG
— Nature Portfolio (@NaturePortfolio) April 12, 2022
Cohort Study: Increased thoracic aortic diameter is associated with increased risk of cardiovascular events and mortality among women and men.
13 Apr, 2022 | 10:20h | UTCThoracic Aortic Diameter and Cardiovascular Events and Mortality among Women and Men – Radiology
News Release: Increased aortic diameter raises risk of heart attack, stroke – Radiological Society of North America
RCT: In patients undergoing knee replacement surgery, the administration of periarticular liposomal bupivacaine did not improve postoperative recovery or pain compared with bupivacaine hydrochloride alone.
13 Apr, 2022 | 10:16h | UTC
Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis.
13 Apr, 2022 | 10:15h | UTC
M-A: Adverse perinatal outcomes associated with protease inhibitor-based antiretroviral therapy in pregnant women living with HIV.
13 Apr, 2022 | 10:18h | UTCNews Release: Protease inhibitors safer than thought for pregnant women with HIV – University of Oxford
Brief review | Infective endocarditis: words of caution for management.
13 Apr, 2022 | 10:12h | UTCInfective Endocarditis: Words of Caution For Management – American College of Cardiology
Related:
Randomized Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis
Podcast: Infective Endocarditis Pearls.
Review: Infective endocarditis after surgical and transcatheter aortic valve replacement
Infective Endocarditis: A Contemporary Review
Summary: Current AATS Guidelines on Surgical Treatment of Infective Endocarditis
Review: Current Evidence on Oral Antibiotics for Infective Endocarditis
Research: Invasive Procedures Associated With the Development of Infective Endocarditis
Prosthetic Valve Endocarditis After Surgical Aortic Valve Replacement
Interplay of mineralocorticoid receptor antagonists and Empagliflozin in heart failure: Secondary analysis of the EMPEROR-Reduced trial.
13 Apr, 2022 | 10:14h | UTCEditorial: Quadruple Medical Therapy for Heart Failure: Medications Working Together to Provide the Best Care
RCT: Prophylactic Rivaroxaban for 30 days to prevent left ventricular thrombus after anterior ST-Segment Elevation Myocardial Infarction.
13 Apr, 2022 | 09:56h | UTCProphylactic Rivaroxaban Therapy for Left Ventricular Thrombus After Anterior ST-Segment Elevation Myocardial Infarction – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Drug resistant TB – latest developments in epidemiology, diagnostics and management.
13 Apr, 2022 | 10:09h | UTCRelated:
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment
Canadian Tuberculosis Standards – 8th Edition.
Guideline: Treatment of Drug-Resistant Tuberculosis
The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis
Regimens to Treat Multidrug-resistant Tuberculosis: Past, Present and Future Perspectives
New WHO online course: Monkeypox epidemiology, preparedness and response.
13 Apr, 2022 | 10:03h | UTCMonkeypox epidemiology, preparedness and response – OpenWHO
Commentary on Twitter
Monkeypox remains an under-recognized and underreported emerging disease. Good clinical management can limit disease severity or death.
Learn about prevention and control of #monkeypox in our ? free online course on #OpenWHO:
? https://t.co/3MtOCbiVoI pic.twitter.com/o1NabpyEzD— World Health Organization (WHO) (@WHO) April 10, 2022
M-A: Three-port vs. four-port technique for laparoscopic cholecystectomy.
13 Apr, 2022 | 10:02h | UTC
Commentary on Twitter
Laparoscopic cholecystectomy: 3 port ?? 4 port
? Syst review meta-analysis of 18 trials
? length procedure and adverse events
⌛️ 3 ports LOS 0.3 days less ?? Use of 3 ports should not be at the expense of safe dissection of Calot’s trianglehttps://t.co/yumsSJpPFt pic.twitter.com/qgNMQitY0e
— Giovanni Marchegiani (@Gio_Marchegiani) April 9, 2022
Study identifies which treatments are associated with an increased risk of heart disease among women with breast cancer.
13 Apr, 2022 | 10:00h | UTCRisk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Major study links breast cancer treatment with increased risk of cardiovascular disease – Fred Hutch
Commentary on Twitter
Great case-control study in a modern cohort evaluating long-term cardiovascular disease after #breastcancer treatment. HR for heart failure/cardiomyopathy higher for anthracyclines (HR=1.84) and herceptin (HR=2.53) than for #radiotherapy (HR=1.38). #bcsmhttps://t.co/ZEVfbwlepr
— Shane Stecklein, MD, PhD (@shanestecklein) April 8, 2022
Seminar: Cholera.
13 Apr, 2022 | 09:55h | UTCCholera – The Lancet (free registration required)